| A SARS-CoV-2 protein interaction map reveals targets for drug repurposing DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, KM White, ... Nature 583 (7816), 459-468, 2020 | 2892 | 2020 |
| The Rosetta all-atom energy function for macromolecular modeling and design RF Alford, A Leaver-Fay, JR Jeliazkov, MJ O’Meara, FP DiMaio, H Park, ... Journal of chemical theory and computation 13 (6), 3031-3048, 2017 | 688 | 2017 |
| Ultra-large library docking for discovering new chemotypes J Lyu, S Wang, TE Balius, I Singh, A Levit, YS Moroz, MJ O’Meara, T Che, ... Nature 566 (7743), 224-229, 2019 | 380 | 2019 |
| Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ... Science 370 (6521), eabe9403, 2020 | 325 | 2020 |
| Combined Covalent-Electrostatic Model of Hydrogen Bonding Improves Structure Prediction with Rosetta MJ O’Meara, A Leaver-Fay, MD Tyka, A Stein, K Houlihan, F DiMaio, ... Journal of chemical theory and computation 11 (2), 609-622, 2015 | 205 | 2015 |
| Scientific benchmarks for guiding macromolecular energy function improvement A Leaver-Fay, MJ O’Meara, M Tyka, R Jacak, Y Song, EH Kellogg, ... Methods in enzymology 523, 2013 | 205 | 2013 |
| Morphological cell profiling of SARS-CoV-2 infection identifies drug repurposing candidates for COVID-19 C Mirabelli, JW Wotring, CJ Zhang, SM McCarty, R Fursmidt, CD Pretto, ... Proceedings of the National Academy of Sciences 118 (36), 2021 | 99 | 2021 |
| The Cryptococcus neoformans Rim101 transcription factor directly regulates genes required for adaptation to the host TR O'Meara, W Xu, KM Selvig, MJ O'Meara, AP Mitchell, JA Alspaugh Molecular and Cellular Biology 34 (4), 673-684, 2014 | 80 | 2014 |
| Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2 TA Tummino, VV Rezelj, B Fischer, A Fischer, MJ O’Meara, B Monel, ... Science 373 (6554), 541-547, 2021 | 76 | 2021 |
| The recognition of identical ligands by unrelated proteins S Barelier, T Sterling, MJ O’Meara, BK Shoichet ACS chemical biology 10 (12), 2772-2784, 2015 | 59 | 2015 |
| A web resource for standardized benchmark datasets, metrics, and Rosetta protocols for macromolecular modeling and design S Ó Conchúir, KA Barlow, RA Pache, N Ollikainen, K Kundert, ... PLOS one 10 (9), e0130433, 2015 | 59 | 2015 |
| Role of Electrostatic Repulsion in Controlling pH-Dependent Conformational Changes of Viral Fusion Proteins JS Harrison, CD Higgins, MJ O’Meara, JF Koellhoffer, BA Kuhlman, ... Structure 21 (7), 1085-1096, 2013 | 54 | 2013 |
| High-Throughput Screening Identifies Genes Required for Candida albicans Induction of Macrophage Pyroptosis TR O’Meara, K Duah, CX Guo, ME Maxson, RG Gaudet, K Koselny, ... MBio 9 (4), e01581-18, 2018 | 41 | 2018 |
| Global proteomic analyses define an environmentally contingent Hsp90 interactome and reveal chaperone-dependent regulation of stress granule proteins and the R2TP complex in a … TR O’Meara, MJ O’Meara, EJ Polvi, MR Pourhaghighi, SD Liston, ZY Lin, ... PLoS biology 17 (7), e3000358, 2019 | 30 | 2019 |
| Prediction of enzymatic pathways by integrative pathway mapping S Calhoun, M Korczynska, DJ Wichelecki, B San Francisco, S Zhao, ... eLife 7, e31097, 2018 | 27 | 2018 |
| Local delivery of stabilized chondroitinase ABC degrades chondroitin sulfate proteoglycans in stroke-injured rat brains MH Hettiaratchi, MJ O'Meara, CJ Teal, SL Payne, AJ Pickering, ... Journal of Controlled Release 297, 14-25, 2019 | 25 | 2019 |
| A Unified Stochastic Gradient Approach to Designing Bayesian-Optimal Experiments A Foster, M Jankowiak, M O’Meara, YW Teh, T Rainforth International Conference on Artificial Intelligence and Statistics, 2959-2969, 2020 | 18 | 2020 |
| Ligand similarity complements sequence, physical interaction, and co-expression for gene function prediction MJ O’Meara, S Ballouz, BK Shoichet, J Gillis PloS one 11 (7), e0160098, 2016 | 16 | 2016 |
| Structures of the σ2 receptor enable docking for bioactive ligand discovery A Alon, J Lyu, JM Braz, TA Tummino, V Craik, MJ O’Meara, CM Webb, ... Nature 600 (7890), 759-764, 2021 | 14* | 2021 |
| Property-Unmatched Decoys in Docking Benchmarks RM Stein, Y Yang, TE Balius, MJ O’Meara, J Lyu, J Young, K Tang, ... Journal of Chemical Information and Modeling 61 (2), 699-714, 2021 | 14 | 2021 |
Brian ShoichetProfessor of Pharmaceutical Chemistry, University of California, San FranciscoVerified email at cgl.ucsf.edu
