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Joseph Pilewski
Joseph Pilewski
Verified email at upmc.edu
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Year
IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia
SJ Aujla, YR Chan, M Zheng, M Fei, DJ Askew, DA Pociask, TA Reinhart, ...
Nature medicine 14 (3), 275-281, 2008
14872008
Effect of VX-770 in Persons with Cystic Fibrosis and the G551D-CFTR Mutation
FJ Accurso, SM Rowe, JP Clancy, MP Boyle, JM Dunitz, PR Durie, ...
New England Journal of Medicine 363 (21), 1991-2003, 2010
9132010
Results of a phase IIa study of VX-809, an investigational CFTR corrector compound, in subjects with cystic fibrosis homozygous for the F508del-CFTR mutation
JP Clancy, SM Rowe, FJ Accurso, ML Aitken, RS Amin, MA Ashlock, ...
Thorax 67 (1), 12-18, 2012
6492012
Role of CFTR in airway disease
JM Pilewski, RA Frizzell
Physiological reviews 79 (1), S215-S255, 1999
6221999
Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth-related oncogene-α and granulocyte colony-stimulating factor in bronchial epithelium: implications for …
F McAllister, A Henry, JL Kreindler, PJ Dubin, L Ulrich, C Steele, ...
The Journal of Immunology 175 (1), 404-412, 2005
5312005
Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease
ZH Chen, HP Kim, FC Sciurba, SJ Lee, C Feghali-Bostwick, DB Stolz, ...
PloS one 3 (10), e3316, 2008
5162008
Comprehensive gene expression profiles reveal pathways related to the pathogenesis of chronic obstructive pulmonary disease
W Ning, CJ Li, N Kaminski, CA Feghali-Bostwick, SM Alber, YP Di, ...
Proceedings of the National Academy of Sciences 101 (41), 14895-14900, 2004
3952004
Autoantibodies in patients with chronic obstructive pulmonary disease
CA Feghali-Bostwick, AS Gadgil, LE Otterbein, JM Pilewski, MW Stoner, ...
American journal of respiratory and critical care medicine 177 (2), 156-163, 2008
3932008
High IFN-γ and low SLPI mark severe asthma in mice and humans
M Raundhal, C Morse, A Khare, TB Oriss, J Milosevic, J Trudeau, R Huff, ...
The Journal of clinical investigation 125 (8), 3037-3050, 2015
3682015
Epithelial Na+ channels are fully activated by furin-and prostasin-dependent release of an inhibitory peptide from the γ-subunit
JB Bruns, MD Carattino, S Sheng, AB Maarouf, OA Weisz, JM Pilewski, ...
Journal of Biological Chemistry 282 (9), 6153-6160, 2007
3502007
Repeated aerosolized AAV-CFTR for treatment of cystic fibrosis: a randomized placebo-controlled phase 2B trial
RB Moss, C Milla, J Colombo, F Accurso, PL Zeitlin, JP Clancy, ...
Human gene therapy 18 (8), 726-732, 2007
3252007
T lymphocytes adhere to airway smooth muscle cells via integrins and CD44 and induce smooth muscle cell DNA synthesis.
AL Lazaar, SM Albelda, JM Pilewski, B Brennan, E Puré, RA Panettieri Jr
The Journal of experimental medicine 180 (3), 807-816, 1994
3041994
Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis
DM Hutt, D Herman, APC Rodrigues, S Noel, JM Pilewski, J Matteson, ...
Nature chemical biology 6 (1), 25-33, 2010
2832010
Insulin-like growth factor binding proteins 3 and 5 are overexpressed in idiopathic pulmonary fibrosis and contribute to extracellular matrix deposition
JM Pilewski, L Liu, AC Henry, AV Knauer, CA Feghali-Bostwick
The American journal of pathology 166 (2), 399-407, 2005
2632005
Insulin therapy to improve BMI in cystic fibrosis–related diabetes without fasting hyperglycemia: results of the Cystic Fibrosis Related Diabetes Therapy Trial
A Moran, P Pekow, P Grover, M Zorn, B Slovis, J Pilewski, E Tullis, ...
Diabetes care 32 (10), 1783-1788, 2009
2532009
Voriconazole prophylaxis in lung transplant recipients
S Husain, DL Paterson, S Studer, J Pilewski, M Crespo, D Zaldonis, ...
American Journal of Transplantation 6 (12), 3008-3016, 2006
2372006
Efficacy of extracorporeal membrane oxygenation as a bridge to lung transplantation
Y Toyoda, JK Bhama, N Shigemura, D Zaldonis, J Pilewski, M Crespo, ...
The Journal of thoracic and cardiovascular surgery 145 (4), 1065-1071, 2013
2362013
Lung tissues in patients with systemic sclerosis have gene expression patterns unique to pulmonary fibrosis and pulmonary hypertension
E Hsu, H Shi, RM Jordan, J Lyons‐Weiler, JM Pilewski, ...
Arthritis & Rheumatism 63 (3), 783-794, 2011
2352011
Patients with idiopathic pulmonary fibrosis with antibodies to heat shock protein 70 have poor prognoses
RA Kahloon, J Xue, A Bhargava, E Csizmadia, L Otterbein, DJ Kass, ...
American journal of respiratory and critical care medicine 187 (7), 768-775, 2013
2152013
Aspergillus galactomannan antigen in the bronchoalveolar lavage fluid for the diagnosis of invasive aspergillosis in lung transplant recipients
S Husain, DL Paterson, SM Studer, M Crespo, J Pilewski, M Durkin, ...
Transplantation 83 (10), 1330-1336, 2007
2132007
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