Hanoch Kaphzan
Hanoch Kaphzan
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Exaggerated translation causes synaptic and behavioural aberrations associated with autism
E Santini, TN Huynh, AF MacAskill, AG Carter, P Pierre, D Ruggero, ...
Nature 493 (7432), 411-415, 2013
Genetic removal of p70 S6 kinase 1 corrects molecular, synaptic, and behavioral phenotypes in fragile X syndrome mice
A Bhattacharya, H Kaphzan, AC Alvarez-Dieppa, JP Murphy, P Pierre, ...
Neuron 76 (2), 325-337, 2012
Macroautophagy deficiency mediates age-dependent neurodegeneration through a phospho-tau pathway
K Inoue, J Rispoli, H Kaphzan, E Klann, EI Chen, J Kim, M Komatsu, ...
Molecular neurodegeneration 7, 1-13, 2012
Brain-specific disruption of the eIF2α kinase PERK decreases ATF4 expression and impairs behavioral flexibility
MA Trinh, H Kaphzan, RC Wek, P Pierre, DR Cavener, E Klann
Cell reports 1 (6), 676-688, 2012
Alterations in intrinsic membrane properties and the axon initial segment in a mouse model of Angelman syndrome
H Kaphzan, SA Buffington, JI Jung, MN Rasband, E Klann
Journal of Neuroscience 31 (48), 17637-17648, 2011
Genetic and acute CPEB1 depletion ameliorate fragile X pathophysiology
T Udagawa, NG Farny, M Jakovcevski, H Kaphzan, JM Alarcon, ...
Nature medicine 19 (11), 1473-1477, 2013
A molecular switch for translational control in taste memory consolidation
K Belelovsky, A Elkobi, H Kaphzan, AC Nairn, K Rosenblum
European Journal of Neuroscience 22 (10), 2560-2568, 2005
Neuromodulation of axon terminals
D Chakraborty, DQ Truong, M Bikson, H Kaphzan
Cerebral Cortex 28 (8), 2786-2794, 2018
Neuronal CTCF is necessary for basal and experience-dependent gene regulation, memory formation, and genomic structure of BDNF and Arc
DS Sams, S Nardone, D Getselter, D Raz, M Tal, PR Rayi, H Kaphzan, ...
Cell reports 17 (9), 2418-2430, 2016
Reversal of impaired hippocampal long-term potentiation and contextual fear memory deficits in Angelman syndrome model mice by ErbB inhibitors
H Kaphzan, P Hernandez, JI Jung, KK Cowansage, K Deinhardt, ...
Biological psychiatry 72 (3), 182-190, 2012
Local inhibition of PERK enhances memory and reverses age-related deterioration of cognitive and neuronal properties
V Sharma, H Ounallah-Saad, D Chakraborty, M Hleihil, R Sood, I Barrera, ...
Journal of Neuroscience 38 (3), 648-658, 2018
Metabotropic glutamate receptor-dependent long-term depression is impaired due to elevated ERK signaling in the ΔRG mouse model of tuberous sclerosis complex
I Chévere-Torres, H Kaphzan, A Bhattacharya, A Kang, JM Maki, ...
Neurobiology of disease 45 (3), 1101-1110, 2012
Genetic reduction of the α1 subunit of Na/K-ATPase corrects multiple hippocampal phenotypes in Angelman syndrome
H Kaphzan, SA Buffington, AB Ramaraj, JB Lingrel, MN Rasband, ...
Cell reports 4 (3), 405-412, 2013
Biphasic activation of the mTOR pathway in the gustatory cortex is correlated with and necessary for taste learning
K Belelovsky, H Kaphzan, A Elkobi, K Rosenblum
Journal of Neuroscience 29 (23), 7424-7431, 2009
The eIF2α kinase PERK limits the expression of hippocampal metabotropic glutamate receptor-dependent long-term depression
MA Trinh, T Ma, H Kaphzan, A Bhattacharya, MD Antion, DR Cavener, ...
Learning & memory 21 (5), 298-304, 2014
Mitochondrial superoxide contributes to hippocampal synaptic dysfunction and memory deficits in Angelman syndrome model mice
E Santini, KL Turner, AB Ramaraj, MP Murphy, E Klann, H Kaphzan
Journal of Neuroscience 35 (49), 16213-16220, 2015
GABAergic synapses at the axon initial segment of basolateral amygdala projection neurons modulate fear extinction
R Saha, S Knapp, D Chakraborty, O Horovitz, A Albrecht, M Kriebel, ...
Neuropsychopharmacology 42 (2), 473-484, 2017
Glutamate dehydrogenase–deficient mice display schizophrenia-like behavioral abnormalities and CA1-specific hippocampal dysfunction
SS Lander, U Khan, N Lewandowski, D Chakraborty, FA Provenzano, ...
Schizophrenia bulletin 45 (1), 127-137, 2019
Sex-dependent sensory phenotypes and related transcriptomic expression profiles are differentially affected by Angelman syndrome
L Koyavski, J Panov, L Simchi, PR Rayi, L Sharvit, Y Feuermann, ...
Molecular Neurobiology 56, 5998-6016, 2019
NMDA and dopamine converge on the NMDA-receptor to induce ERK activation and synaptic depression in mature hippocampus
H Kaphzan, KJ O'Riordan, KP Mangan, JM Levenson, K Rosenblum
PLoS One 1 (1), e138, 2006
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