Essential iris atrophy, pigment dispersion, and glaucoma in DBA/2J mice. SW John, RS Smith, OV Savinova, NL Hawes, B Chang, D Turnbull, ... Investigative ophthalmology & visual science 39 (6), 951-962, 1998 | 662 | 1998 |
Inherited glaucoma in DBA/2J mice: pertinent disease features for studying the neurodegeneration RT Libby, MG Anderson, I Pang, ZH Robinson, OV Savinova, IM Cosma, ... Visual neuroscience 22 (5), 637-648, 2005 | 445 | 2005 |
Susceptibility to Neurodegeneration in a Glaucoma Is Modified by Bax Gene Dosage RT Libby, Y Li, OV Savinova, J Barter, RS Smith, RW Nickells, SWM John PLoS genetics 1 (1), e4, 2005 | 420 | 2005 |
Fish oil—how does it reduce plasma triglycerides? GC Shearer, OV Savinova, WS Harris Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2012 | 378 | 2012 |
Haploinsufficiency of the transcription factors FOXC1 and FOXC2 results in aberrant ocular development RS Smith, A Zabaleta, T Kume, OV Savinova, SH Kidson, JE Martin, ... Human molecular genetics 9 (7), 1021-1032, 2000 | 365 | 2000 |
Interacting loci cause severe iris atrophy and glaucoma in DBA/2J mice B Chang, RS Smith, NL Hawes, MG Anderson, A Zabaleta, O Savinova, ... Nature genetics 21 (4), 405-409, 1999 | 332 | 1999 |
Targeted Disruption of the Myocilin Gene (Myoc) Suggests that Human Glaucoma-Causing Mutations Are Gain of Function BS Kim, OV Savinova, MV Reedy, J Martin, Y Lun, L Gan, RS Smith, ... Molecular and cellular biology 21 (22), 7707-7713, 2001 | 310 | 2001 |
Modification of ocular defects in mouse developmental glaucoma models by tyrosinase RT Libby, RS Smith, OV Savinova, A Zabaleta, JE Martin, FJ Gonzalez, ... Science 299 (5612), 1578-1581, 2003 | 279 | 2003 |
Intraocular pressure in genetically distinct mice: an update and strain survey OV Savinova, F Sugiyama, JE Martin, SI Tomarev, BJ Paigen, RS Smith, ... BMC genetics 2 (1), 1-15, 2001 | 222 | 2001 |
The 20S proteasome processes NF‐κB1 p105 into p50 in a translation‐independent manner AK Moorthy, OV Savinova, JQ Ho, VYF Wang, D Vu, G Ghosh The EMBO journal 25 (9), 1945-1956, 2006 | 201 | 2006 |
The Nfkb1 and Nfkb2 proteins p105 and p100 function as the core of high-molecular-weight heterogeneous complexes OV Savinova, A Hoffmann, G Ghosh Molecular cell 34 (5), 591-602, 2009 | 199 | 2009 |
Haploinsufficient Bmp4 ocular phenotypes include anterior segment dysgenesis with elevated intraocular pressure B Chang, RS Smith, M Peters, OV Savinova, NL Hawes, A Zabaleta, ... BMC genetics 2 (1), 1-12, 2001 | 188 | 2001 |
The mouse anterior chamber angle and trabecular meshwork develop without cell death RS Smith, A Zabaleta, OV Savinova, SWM John BMC developmental biology 1 (1), 1-14, 2001 | 169 | 2001 |
Genetically Increasing Myoc Expression Supports a Necessary Pathologic Role of Abnormal Proteins in Glaucoma DB Gould, L Miceli-Libby, OV Savinova, M Torrado, SI Tomarev, RS Smith, ... Molecular and cellular biology 24 (20), 9019-9025, 2004 | 152 | 2004 |
Col4a1 mutation causes endoplasmic reticulum stress and genetically modifiable ocular dysgenesis DB Gould, JK Marchant, OV Savinova, RS Smith, SWM John Human molecular genetics 16 (7), 798-807, 2007 | 144 | 2007 |
By altering ocular immune privilege, bone marrow–derived cells pathogenically contribute to DBA/2J pigmentary glaucoma JS Mo, MG Anderson, M Gregory, RS Smith, OV Savinova, DV Serreze, ... The Journal of experimental medicine 197 (10), 1335-1344, 2003 | 131 | 2003 |
Kinetic control of negative feedback regulators of NF-κB/RelA determines their pathogen-and cytokine-receptor signaling specificity VFS Shih, JD Kearns, S Basak, OV Savinova, G Ghosh, A Hoffmann Proceedings of the National Academy of Sciences 106 (24), 9619-9624, 2009 | 130 | 2009 |
Genetic modification of glaucoma associated phenotypes between AKXD-28/Ty and DBA/2J mice MG Anderson, RS Smith, OV Savinova, NL Hawes, B Chang, A Zabaleta, ... BMC genetics 2 (1), 1-12, 2001 | 100 | 2001 |
Transgenic Overexpression of Tissue‐Nonspecific Alkaline Phosphatase (TNAP) in Vascular Endothelium Results in Generalized Arterial Calcification AY Savinov, M Salehi, MC Yadav, I Radichev, JL Millán, OV Savinova Journal of the American Heart Association 4 (12), e002499, 2015 | 94 | 2015 |
Stabilization of RelB requires multidomain interactions with p100/p52 AJ Fusco, OV Savinova, R Talwar, JD Kearns, A Hoffmann, G Ghosh Journal of Biological Chemistry 283 (18), 12324-12332, 2008 | 91 | 2008 |