עקוב אחר
Anneli Nordqvist
Anneli Nordqvist
Cardiovascular and Metabolic Diseases, Innovative Medicines and Early Development Biotech Unit, AstraZeneca
כתובת אימייל מאומתת בדומיין astrazeneca.com
כותרת
צוטט על ידי
צוטט על ידי
שנה
Functionalized 3-amino-imidazo [1, 2-a] pyridines: a novel class of drug-like Mycobacterium tuberculosis glutamine synthetase inhibitors
LR Odell, MT Nilsson, J Gising, O Lagerlund, D Muthas, A Nordqvist, ...
Bioorganic & Medicinal Chemistry Letters 19 (16), 4790-4793, 2009
1292009
Virtual screening and bioassay study of novel inhibitors for dengue virus mRNA cap (nucleoside-2′ O)-methyltransferase
VB Luzhkov, B Selisko, A Nordqvist, F Peyrane, E Decroly, K Alvarez, ...
Bioorganic & medicinal chemistry 15 (24), 7795-7802, 2007
952007
Synthesis of Functionalized Cinnamaldehyde Derivatives by an Oxidative Heck Reaction and Their Use as Starting Materials for Preparation of Mycobacterium tuberculosis 1 …
A Nordqvist, C Björkelid, M Andaloussi, AM Jansson, SL Mowbray, ...
The Journal of Organic Chemistry 76 (21), 8986-8998, 2011
772011
Links between bacterial production, amino-acid utilization and community composition in productive lakes
S Bertilsson, A Eiler, A Nordqvist, NOG Jørgensen
The ISME journal 1 (6), 532-544, 2007
642007
A general model for prediction of Caco‐2 cell permeability
A Nordqvist, J Nilsson, T Lindmark, A Eriksson, P Garberg, M Kihlén
QSAR & Combinatorial Science 23 (5), 303-310, 2004
492004
Synthesis, biological evaluation and X-ray crystallographic studies of imidazo [1, 2-a] pyridine-based Mycobacterium tuberculosis glutamine synthetase inhibitors
A Nordqvist, MT Nilsson, O Lagerlund, D Muthas, J Gising, S Yahiaoui, ...
MedChemComm 3 (5), 620-626, 2012
482012
Evaluation of the amino acid binding site of Mycobacterium tuberculosis glutamine synthetase for drug discovery
A Nordqvist, MT Nilsson, S Röttger, LR Odell, WW Krajewski, ...
Bioorganic & medicinal chemistry 16 (10), 5501-5513, 2008
442008
GPR103 Antagonists Demonstrating Anorexigenic Activity in Vivo: Design and Development of Pyrrolo[2,3-c]pyridines That Mimic the C-Terminal Arg-Phe Motif of …
J Georgsson, F Bergström, A Nordqvist, MJ Watson, CD Blundell, ...
Journal of Medicinal Chemistry 57 (14), 5935-5948, 2014
27*2014
Protease-activated receptor-2 ligands reveal orthosteric and allosteric mechanisms of receptor inhibition
AJ Kennedy, L Sundström, S Geschwindner, EKY Poon, Y Jiang, R Chen, ...
Communications biology 3 (1), 782, 2020
262020
Quantitative structure–activity relationships of pine weevil antifeedants, a multivariate approach
K Sunnerheim, A Nordqvist, G Nordlander, AK Borg-Karlson, CR Unelius, ...
Journal of agricultural and food chemistry 55 (23), 9365-9372, 2007
262007
Discovery of retinoic acid receptor agonists as proliferators of cardiac progenitor cells through a phenotypic screening approach
L Drowley, J McPheat, A Nordqvist, S Peel, U Karlsson, S Martinsson, ...
Stem cells translational medicine 9 (1), 47-60, 2020
222020
Phenotypic screen for cardiac regeneration identifies molecules with differential activity in human epicardium-derived cells versus cardiac fibroblasts
AI Paunovic, L Drowley, A Nordqvist, E Ericson, E Mouchet, A Jonebring, ...
ACS Chemical Biology 12 (1), 132-141, 2017
212017
Differential expression of IGF-I and IGF-binding protein-1 and-2 in periportal and perivenous zones of rat liver
SJ Hazel, ACS Nordqvist, K Hall, M Nilsson, M Schalling
Journal of endocrinology 157 (2), 285-294, 1998
201998
Identification of mineralocorticoid receptor modulators with low impact on electrolyte homeostasis but maintained organ protection
KL Granberg, ZQ Yuan, B Lindmark, K Edman, J Kajanus, A Hogner, ...
Journal of Medicinal Chemistry 62 (3), 1385-1406, 2018
192018
Neuropeptide 26RFa (QRFP) is a key regulator of glucose homeostasis and its activity is markedly altered in obese/hyperglycemic mice
G Prévost, A Arabo, MA Le Solliec, J Bons, M Picot, J Maucotel, ...
American Journal of Physiology-Endocrinology and Metabolism 317 (1), E147-E157, 2019
172019
Microwave-enhanced α-arylation of a protected glycine in water: Evaluation of 3-phenylglycine derivatives as inhibitors of the tuberculosis enzyme, glutamine synthetase
O Lagerlund, LR Odell, SL Mowbray, MT Nilsson, WW Krajewski, ...
Combinatorial chemistry & high throughput screening 10 (9), 783-789, 2007
152007
Structure‐Based Drug Design of Mineralocorticoid Receptor Antagonists to Explore Oxosteroid Receptor Selectivity
A Nordqvist, G O'Mahony, M Fridén‐Saxin, M Fredenwall, A Hogner, ...
ChemMedChem 12 (1), 50-65, 2017
132017
Structural characterization of agonist binding to protease-activated receptor 2 through mutagenesis and computational modeling
AJ Kennedy, F Ballante, JR Johansson, G Milligan, L Sundström, ...
ACS Pharmacology & Translational Science 1 (2), 119-133, 2018
102018
New hits as antagonists of GPR103 identified by HTS
A Nordqvist, L Kristensson, KE Johansson, K Isaksson da Silva, T Fex, ...
ACS Medicinal Chemistry Letters 5 (5), 527-532, 2014
92014
Predicting the relative binding affinity of mineralocorticoid receptor antagonists by density functional methods
K Roos, A Hogner, D Ogg, MJ Packer, E Hansson, KL Granberg, ...
Journal of computer-aided molecular design 29, 1109-1122, 2015
82015
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מאמרים 1–20