Yehuda G. Assaraf
Yehuda G. Assaraf
Professor of Cancer Research, Technion, Haifa Israel
אין אימייל מאומת
צוטט על ידי
צוטט על ידי
Antifolate resistance mediated by the multidrug resistance proteins MRP1 and MRP2
JH Hooijberg, HJ Broxterman, M Kool, YG Assaraf, GJ Peters, ...
Cancer Research 59 (11), 2532-2535, 1999
Molecular basis of bortezomib resistance: proteasome subunit β5 (PSMB5) gene mutation and overexpression of PSMB5 protein
R Oerlemans, NE Franke, YG Assaraf, J Cloos, I van Zantwijk, CR Berkers, ...
Blood 112 (6), 2489-2499, 2008
Nanomedicine for targeted cancer therapy: towards the overcoming of drug resistance
A Shapira, YD Livney, HJ Broxterman, YG Assaraf
Drug resistance updates 14 (3), 150-163, 2011
Molecular basis of antifolate resistance
YG Assaraf
Cancer and Metastasis Reviews 26 (1), 153-181, 2007
Antifolates in cancer therapy: structure, activity and mechanisms of drug resistance
N Gonen, YG Assaraf
Drug Resistance Updates 15 (4), 183-210, 2012
Overcoming ABC transporter-mediated multidrug resistance: molecular mechanisms and novel therapeutic drug strategies
W Li, H Zhang, YG Assaraf, K Zhao, X Xu, J Xie, DH Yang, ZS Chen
Drug Resistance Updates 27, 14-29, 2016
Lysosomal sequestration of sunitinib: a novel mechanism of drug resistance
KJ Gotink, HJ Broxterman, M Labots, RR De Haas, H Dekker, ...
Clinical Cancer Research 17 (23), 7337-7346, 2011
The folate receptor as a rational therapeutic target for personalized cancer treatment
YG Assaraf, CP Leamon, JA Reddy
Drug Resistance Updates 17 (4-6), 89-95, 2014
The role of multidrug resistance efflux transporters in antifolate resistance and folate homeostasis
YG Assaraf
Drug Resistance Updates 9 (4-5), 227-246, 2006
The role of passive transbilayer drug movement in multidrug resistance and its modulation
GD Eytan, R Regev, G Oren, YG Assaraf
Journal of biological chemistry 271 (22), 12897-12902, 1996
Cyclic nucleotide-binding domains in proteins having diverse functions
JB Shabb, JD Corbin
The Journal of biological chemistry (Print) 267 (9), 5723-5726, 1992
Potentiation of anticancer‐drug cytotoxicity by multidrug‐resistance chemosensitizers involves alterationsin membrane fluidity leading to increased membrane permeability
S Drori, GD Eytan, YG Assaraf
European journal of biochemistry 228 (3), 1020-1029, 1995
Lysosomes as mediators of drug resistance in cancer
B Zhitomirsky, YG Assaraf
Drug Resistance Updates 24, 23-33, 2016
Membrane fluidization by ether, other anesthetics, and certain agents abolishes P‐glycoprotein ATPase activity and modulates efflux from multidrug‐resistant cells
R Regev, YG Assaraf, GD Eytan
European journal of biochemistry 259 (1‐2), 18-24, 1999
Competition of hydrophobic peptides, cytotoxic drugs, and chemosensitizers on a common P-glycoprotein pharmacophore as revealed by its ATPase activity
MJ Borgnia, GD Eytan, YG Assaraf
Journal of Biological Chemistry 271 (6), 3163-3171, 1996
A structurally altered human reduced folate carrier with increased folic acid transport mediates a novel mechanism of antifolate resistance
G Jansen, R Mauritz, S Drori, H Sprecher, I Kathmann, M Bunni, DG Priest, ...
Journal of Biological Chemistry 273 (46), 30189-30198, 1998
Impaired bortezomib binding to mutant β5 subunit of the proteasome is the underlying basis for bortezomib resistance in leukemia cells
NE Franke, D Niewerth, YG Assaraf, J van Meerloo, K Vojtekova, ...
Leukemia 26 (4), 757-768, 2012
Rationally designed nanovehicles to overcome cancer chemoresistance
YD Livney, YG Assaraf
Advanced drug delivery reviews 65 (13-14), 1716-1730, 2013
Folate deprivation results in the loss of breast cancer resistance protein (BCRP/ABCG2) expression: a role for BCRP in cellular folate homeostasis
I Ifergan, A Shafran, G Jansen, JH Hooijberg, GL Scheffer, YG Assaraf
Journal of Biological Chemistry 279 (24), 25527-25534, 2004
Microenvironment acidity as a major determinant of tumor chemoresistance: Proton pump inhibitors (PPIs) as a novel therapeutic approach
S Taylor, EP Spugnini, YG Assaraf, T Azzarito, C Rauch, S Fais
Drug Resistance Updates 23, 69-78, 2015
המערכת אינה יכולה לבצע את הפעולה כעת. נסה שוב מאוחר יותר.
מאמרים 1–20