| Proteasome inhibitors: from research tools to drug candidates AF Kisselev, AL Goldberg Chemistry & biology 8 (8), 739-758, 2001 | 1514 | 2001 |
| The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage R Groisman, J Polanowska, I Kuraoka, J Sawada, M Saijo, R Drapkin, ... Cell 113 (3), 357-367, 2003 | 886 | 2003 |
| The sizes of peptides generated from protein by mammalian 26 and 20 S proteasomes: implications for understanding the degradative mechanism and antigen presentation AF Kisselev, TN Akopian, KM Woo, AL Goldberg Journal of Biological Chemistry 274 (6), 3363-3371, 1999 | 823 | 1999 |
| Proteasome inhibitors: an expanding army attacking a unique target AF Kisselev, WA van der Linden, HS Overkleeft Chemistry & biology 19 (1), 99-115, 2012 | 655 | 2012 |
| Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide … HT Kim, KP Kim, F Lledias, AF Kisselev, KM Scaglione, D Skowyra, ... Journal of biological chemistry 282 (24), 17375-17386, 2007 | 609 | 2007 |
| Importance of the different proteolytic sites of the proteasome and the efficacy of inhibitors varies with the protein substrate AF Kisselev, A Callard, AL Goldberg Journal of Biological Chemistry 281 (13), 8582-8590, 2006 | 485 | 2006 |
| 26S proteasomes and immunoproteasomes produce mainly N-extended versions of an antigenic peptide P Cascio, C Hilton, AF Kisselev, KL Rock, AL Goldberg The EMBO journal 20 (10), 2357-2366, 2001 | 483 | 2001 |
| Proteasome active sites allosterically regulate each other, suggesting a cyclical bite-chew mechanism for protein breakdown AF Kisselev, TN Akopian, V Castillo, AL Goldberg Molecular cell 4 (3), 395-402, 1999 | 388 | 1999 |
| Monitoring activity and inhibition of 26S proteasomes with fluorogenic peptide substrates AF Kisselev, AL Goldberg Methods in enzymology 398, 364-378, 2005 | 381 | 2005 |
| CSA-dependent degradation of CSB by the ubiquitin–proteasome pathway establishes a link between complementation factors of the Cockayne syndrome R Groisman, I Kuraoka, O Chevallier, N Gaye, T Magnaldo, K Tanaka, ... Genes & development 20 (11), 1429-1434, 2006 | 299 | 2006 |
| Range of sizes of peptide products generated during degradation of different proteins by archaeal proteasomes AF Kisselev, TN Akopian, AL Goldberg Journal of Biological Chemistry 273 (4), 1982-1989, 1998 | 282 | 1998 |
| Processive degradation of proteins and other catalytic properties of the proteasome from Thermoplasma acidophilum TN Akopian, AF Kisselev, AL Goldberg Journal of Biological Chemistry 272 (3), 1791-1798, 1997 | 269 | 1997 |
| The caspase-like sites of proteasomes, their substrate specificity, new inhibitors and substrates, and allosteric interactions with the trypsin-like sites AF Kisselev, M Garcia-Calvo, HS Overkleeft, E Peterson, MW Pennington, ... Journal of Biological Chemistry 278 (38), 35869-35877, 2003 | 255 | 2003 |
| Binding of hydrophobic peptides to several non-catalytic sites promotes peptide hydrolysis by all active sites of 20 S proteasomes: Evidence for peptide-induced channel opening … AF Kisselev, D Kaganovich, AL Goldberg Journal of Biological Chemistry 277 (25), 22260-22270, 2002 | 236 | 2002 |
| Extended peptide-based inhibitors efficiently target the proteasome and reveal overlapping specificities of the catalytic β-subunits BM Kessler, D Tortorella, M Altun, AF Kisselev, E Fiebiger, BG Hekking, ... Chemistry & biology 8 (9), 913-929, 2001 | 210 | 2001 |
| New insights into the mechanisms and importance of the proteasome in intracellular protein degradation. AL Goldberg, TN Akopian, AF Kisselev, DH Lee, M Rohrwild Biological Chemistry 378 (3-4), 131-140, 1997 | 201 | 1997 |
| Selective inhibitor of proteasome's caspase-like sites sensitizes cells to specific inhibition of chymotrypsin-like sites M Britton, MM Lucas, SL Downey, M Screen, AA Pletnev, M Verdoes, ... Chemistry & biology 16 (12), 1278-1289, 2009 | 191 | 2009 |
| Why does threonine, and not serine, function as the active site nucleophile in proteasomes? AF Kisselev, Z Songyang, AL Goldberg Journal of Biological Chemistry 275 (20), 14831-14837, 2000 | 174 | 2000 |
| Multiple BH3 mimetics antagonize antiapoptotic MCL1 protein by inducing the endoplasmic reticulum stress response and up-regulating BH3-only protein NOXA TC Albershardt, BL Salerni, RS Soderquist, DJP Bates, AA Pletnev, ... Journal of Biological Chemistry 286 (28), 24882-24895, 2011 | 133 | 2011 |
| Specific cell-permeable inhibitor of proteasome trypsin-like sites selectively sensitizes myeloma cells to bortezomib and carfilzomib AC Mirabella, AA Pletnev, SL Downey, BI Florea, TB Shabaneh, M Britton, ... Chemistry & biology 18 (5), 608-618, 2011 | 129 | 2011 |
