| Synthesis and Fluorescence Properties of Manisyl‐Substituted Terpyridine, Bipyridine, and Phenanthroline JC Loren, JS Siegel Angewandte Chemie International Edition 40 (4), 754-757, 2001 | 148 | 2001 |
| Discovery of GNF-5837, a selective TRK inhibitor with efficacy in rodent cancer tumor models P Albaugh, Y Fan, Y Mi, F Sun, F Adrian, N Li, Y Jia, Y Sarkisova, ... ACS Medicinal Chemistry Letters 3 (2), 140-145, 2012 | 119 | 2012 |
| One-Pot Electrochemical Nickel-Catalyzed Decarboxylative Sp2–Sp3 Cross-Coupling T Koyanagi, A Herath, A Chong, M Ratnikov, A Valiere, J Chang, ... Organic letters 21 (3), 816-820, 2019 | 99 | 2019 |
| NH-1, 2, 3-triazoles from azidomethyl pivalate and carbamates: Base-labile N-protecting groups JC Loren, A Krasiński, VV Fokin, KB Sharpless Synlett 2005 (18), 2847-2850, 2005 | 97 | 2005 |
| Synthetic approaches to a molecular Borromean link: two-ring threading with polypyridine templates JC Loren, M Yoshizawa, RF Haldimann, A Linden, JS Siegel Angewandte Chemie-International Edition, 2003 | 95 | 2003 |
| Compounds and compositions as c-kit and PDGFR kinase inhibitors X Li, X Liu, V Molteni, D Chianelli, J Loren, J Nabakka, T Ramsey, ... US Patent 8,338,417, 2012 | 79 | 2012 |
| Compounds and compositions as TRK inhibitors Y Fan, J Loren, V Molteni, PA Albaugh, G Chopiuk, JM Smith, BT Flatt US Patent 8,637,516, 2014 | 72 | 2014 |
| Compounds and compositions as TRK inhibitors V Molteni, Y Fan, J Loren, JM Smith, BT Flatt US Patent 9,102,671, 2015 | 71 | 2015 |
| Synthesis of achiral and racemic catenanes based on terpyridine and a directionalized terpyridine mimic, pyridyl-phenanthroline JC Loren, P Gantzel, A Linden, JS Siegel Organic & Biomolecular Chemistry 3 (17), 3105-3116, 2005 | 66 | 2005 |
| Selective DYRK1A inhibitor for the treatment of Type 1 Diabetes: Discovery of 6-azaindole derivative GNF2133 YA Liu, Q Jin, Y Zou, Q Ding, S Yan, Z Wang, X Hao, B Nguyen, X Zhang, ... Journal of medicinal chemistry 63 (6), 2958-2973, 2020 | 60 | 2020 |
| (R)-2-Phenylpyrrolidine Substituted Imidazopyridazines: A New Class of Potent and Selective Pan-TRK Inhibitors HS Choi, PV Rucker, Z Wang, Y Fan, P Albaugh, G Chopiuk, F Gessier, ... ACS medicinal chemistry letters 6 (5), 562-567, 2015 | 57 | 2015 |
| The banert cascade: A synthetic sequence to polyfunctional NH-1, 2, 3-triazoles JC Loren, KB Sharpless Synthesis 2005 (09), 1514-1520, 2005 | 57 | 2005 |
| Liver X receptor modulators: a review of recently patented compounds (2009–2012) J Loren, Z Huang, BA Laffitte, V Molteni Expert opinion on therapeutic patents 23 (10), 1317-1335, 2013 | 51 | 2013 |
| Compositions and methods for modulating c-kit and PDGFR receptors D Chianelli, C Cow, Y He, S Jiang, X Li, X Liu, Z Liu, J Loren, V Molteni, ... US Patent 7,678,792, 2010 | 45 | 2010 |
| TrkB inhibition by GNF-4256 slows growth and enhances chemotherapeutic efficacy in neuroblastoma xenografts JL Croucher, R Iyer, N Li, V Molteni, J Loren, WP Gordon, T Tuntland, ... Cancer chemotherapy and pharmacology 75, 131-141, 2015 | 42 | 2015 |
| Tuning a Protein‐Labeling Reaction to Achieve Highly Site Selective Lysine Conjugation GH Pham, W Ou, B Bursulaya, M DiDonato, A Herath, Y Jin, X Hao, ... ChemBioChem 19 (8), 799-804, 2018 | 38 | 2018 |
| Synthesis of a D 3-symmetric “trefoil” knotted cyclophane KI Arias, E Zysman-Colman, JC Loren, A Linden, JS Siegel Chemical communications 47 (34), 9588-9590, 2011 | 38 | 2011 |
| Generation and cross-coupling of organozinc reagents in flow A Herath, V Molteni, S Pan, J Loren Organic Letters 20 (23), 7429-7432, 2018 | 30 | 2018 |
| Optimization of platelet-derived growth factor receptor (PDGFR) inhibitors for duration of action, as an inhaled therapy for lung remodeling in pulmonary arterial hypertension DE Shaw, F Baig, I Bruce, S Chamoin, SP Collingwood, S Cross, S Dayal, ... Journal of Medicinal Chemistry 59 (17), 7901-7914, 2016 | 24 | 2016 |
| Androgen Receptor Modulator Compounds and Methods JC Loren, T Miller, B Pedram, CV Rowley, Y Shen, CA Van Oeveren, L Zhi US Patent App. 11/921,366, 2009 | 20 | 2009 |
