Chemically induced degradation of CDK9 by a proteolysis targeting chimera (PROTAC) CM Robb, JI Contreras, S Kour, MA Taylor, M Abid, YA Sonawane, ... Chemical communications 53 (54), 7577-7580, 2017 | 228 | 2017 |
Cyclin dependent kinase 9 inhibitors for cancer therapy: miniperspective YA Sonawane, MA Taylor, JV Napoleon, S Rana, JI Contreras, ... Journal of medicinal chemistry 59 (19), 8667-8684, 2016 | 155 | 2016 |
Selective degradation of CDK6 by a palbociclib based PROTAC S Rana, M Bendjennat, S Kour, HM King, S Kizhake, M Zahid, ... Bioorganic & medicinal chemistry letters 29 (11), 1375-1379, 2019 | 126 | 2019 |
Synthesis and anti-breast cancer activities of substituted quinolines A Shi, TA Nguyen, SK Battina, S Rana, DJ Takemoto, PK Chiang, DH Hua Bioorganic & medicinal chemistry letters 18 (11), 3364-3368, 2008 | 124 | 2008 |
Isatin derived spirocyclic analogues with α-methylene-γ-butyrolactone as anticancer agents: a structure–activity relationship study S Rana, EC Blowers, C Tebbe, JI Contreras, P Radhakrishnan, S Kizhake, ... Journal of medicinal chemistry 59 (10), 5121-5127, 2016 | 108 | 2016 |
Inhibition of Alzheimer’s amyloid toxicity with a tricyclic pyrone molecule in vitro and in vivo HS Hong, S Rana, L Barrigan, A Shi, Y Zhang, F Zhou, LW Jin, DH Hua Journal of neurochemistry 108 (4), 1097-1108, 2009 | 104 | 2009 |
A novel tricyclic pyrone compound ameliorates cell death associated with intracellular amyloid‐β oligomeric complexes I Maezawa, HS Hong, HC Wu, SK Battina, S Rana, T Iwamoto, GA Radke, ... Journal of neurochemistry 98 (1), 57-67, 2006 | 95 | 2006 |
Combining the rapid MTT formazan exocytosis assay and the MC65 protection assay led to the discovery of carbazole analogs as small molecule inhibitors of Aβ oligomer-induced … HS Hong, I Maezawa, N Yao, B Xu, R Diaz-Avalos, S Rana, DH Hua, ... Brain research 1130, 223-234, 2007 | 87 | 2007 |
Small molecule adenosine 5′-monophosphate activated protein kinase (AMPK) modulators and human diseases S Rana, EC Blowers, A Natarajan Journal of medicinal chemistry 58 (1), 2-29, 2015 | 77 | 2015 |
Micellar formulation of indocyanine green for phototherapy of melanoma V Mundra, Y Peng, S Rana, A Natarajan, RI Mahato Journal of Controlled Release 220, 130-140, 2015 | 61 | 2015 |
Selective and irreversible inhibitors of mosquito acetylcholinesterases for controlling malaria and other mosquito-borne diseases YP Pang, F Ekström, GA Polsinelli, Y Gao, S Rana, DH Hua, B Andersson, ... PLoS One 4 (8), e6851, 2009 | 47 | 2009 |
Novel Selective and Irreversible Mosquito Acetylcholinesterase Inhibitors for Controlling Malaria and Other Mosquito-Borne Diseases HJYPP Dengfeng Dou, Jewn Giew Park, Sandeep Rana Nature Scientific Reports 3, 1068, 2013 | 43* | 2013 |
Face selective reduction of the exocyclic double bond in isatin derived spirocyclic lactones S Rana, A Natarajan Org. Biomol. Chem. 11 (2), 244-247, 2013 | 43 | 2013 |
Aminopyrazole based CDK9 PROTAC sensitizes pancreatic cancer cells to venetoclax HM King, S Rana, SP Kubica, JR Mallareddy, S Kizhake, EL Ezell, ... Bioorganic & medicinal chemistry letters 43, 128061, 2021 | 42 | 2021 |
Synthesis and SAR studies of novel 1, 2, 4-oxadiazole-sulfonamide based compounds as potential anticancer agents for colorectal cancer therapy F Shamsi, P Hasan, A Queen, A Hussain, P Khan, B Zeya, HM King, ... Bioorganic Chemistry 98, 103754, 2020 | 42 | 2020 |
Candidate anti-Aβ fluorene compounds selected from analogs of amyloid imaging agents HS Hong, I Maezawa, M Budamagunta, S Rana, A Shi, R Vassar, R Liu, ... Neurobiology of aging 31 (10), 1690-1699, 2010 | 38 | 2010 |
PIK3C3 Inhibition Promotes Sensitivity to Colon Cancer Therapy by Inhibiting Cancer Stem Cells AS Balawant Kumar, Rizwan Ahmad, Swagat Sharma, Saiprasad Gowrikumar, Mark ... Cancers 13 (9), 2168, 2021 | 33 | 2021 |
Explorations of substituted urea functionality for the discovery of new activators of the heme-regulated inhibitor kinase T Chen, K Takrouri, S Hee-Hwang, S Rana, R Yefidoff-Freedman, ... Journal of medicinal chemistry 56 (23), 9457-9470, 2013 | 32 | 2013 |
Combination of nanogel polyethylene glycol-polyethylenimine and 6 (hydroxymethyl)-1, 4-anthracenedione as an anticancer nanomedicine C Ganta, A Shi, SK Battina, M Pyle, S Rana, DH Hua, M Tamura, D Troyer Journal of nanoscience and nanotechnology 8 (5), 2334-2340, 2008 | 31 | 2008 |
Inhibitors, protacs and molecular glues as diverse therapeutic modalities to target cyclin-dependent kinase S Rana, JR Mallareddy, S Singh, L Boghean, A Natarajan Cancers 13 (21), 5506, 2021 | 30 | 2021 |