Evaluation of variability in human kidney organoids B Phipson, XE Pei, AN Combes, TA Forbes, SE Howden, L Zappia, ... Nature methods 16 (1), 79-87, 2019 | 77 | 2019 |
Patient-iPSC-derived kidney organoids show functional validation of a ciliopathic renal phenotype and reveal underlying pathogenetic mechanisms TA Forbes, SE Howden, K Lawlor, B Phipson, J Maksimovic, L Hale, ... The American Journal of Human Genetics 102 (5), 816-831, 2018 | 69 | 2018 |
3D organoid-derived human glomeruli for personalised podocyte disease modelling and drug screening LJ Hale, SE Howden, B Phipson, A Lonsdale, XE Pei, I Ghobrial, ... Nature communications 9 (1), 1-17, 2018 | 57 | 2018 |
Double-stranded RNA is pathogenic in Drosophila models of expanded repeat neurodegenerative diseases KT Lawlor, LV O'Keefe, SE Samaraweera, CL van Eyk, CJ McLeod, ... Human molecular genetics 20 (19), 3757-3768, 2011 | 50 | 2011 |
Single cell analysis of the developing mouse kidney provides deeper insight into marker gene expression and ligand-receptor crosstalk AN Combes, B Phipson, KT Lawlor, A Dorison, R Patrick, L Zappia, ... Development 146 (12), 2019 | 46* | 2019 |
Dermal contributions to human interfollicular epidermal architecture and self-renewal KT Lawlor, P Kaur International journal of molecular sciences 16 (12), 28098-28107, 2015 | 33 | 2015 |
Perturbation of the Akt/Gsk3-β signalling pathway is common to Drosophila expressing expanded untranslated CAG, CUG and AUUCU repeat RNAs CL Van Eyk, LV O'Keefe, KT Lawlor, SE Samaraweera, CJ McLeod, ... Human molecular genetics 20 (14), 2783-2794, 2011 | 32 | 2011 |
Kidney micro-organoids in suspension culture as a scalable source of human pluripotent stem cell-derived kidney cells SV Kumar, XE Pei, KT Lawlor, A Motazedian, M Scurr, I Ghobrial, ... Development 146 (5), 2019 | 21 | 2019 |
Haploinsufficiency for the Six2 gene increases nephron progenitor proliferation promoting branching and nephron number AN Combes, S Wilson, B Phipson, BB Binnie, A Ju, KT Lawlor, C Cebrian, ... Kidney international 93 (3), 589-598, 2018 | 19 | 2018 |
Nephron progenitor commitment is a stochastic process influenced by cell migration KT Lawlor, L Zappia, J Lefevre, JS Park, NA Hamilton, A Oshlack, ... Elife 8, e41156, 2019 | 17 | 2019 |
High throughput single cell RNA-seq of developing mouse kidney and human kidney organoids reveals a roadmap for recreating the kidney AN Combes, B Phipson, L Zappia, KT Lawlor, PX Er, A Oshlack, MH Little bioRxiv, 235499, 2017 | 12 | 2017 |
Bioprinted pluripotent stem cell-derived kidney organoids provide opportunities for high content screening JW Higgins, A Chambon, K Bishard, A Hartung, D Arndt, J Brugnano, ... bioRxiv, 505396, 2018 | 11 | 2018 |
Ubiquitous expression of CUG or CAG trinucleotide repeat RNA causes common morphological defects in a Drosophila model of RNA-mediated pathology KT Lawlor, LV O’Keefe, SE Samaraweera, CL Van Eyk, RI Richards PLoS One 7 (6), e38516, 2012 | 11 | 2012 |
Pericytes promote skin regeneration by inducing epidermal cell polarity and planar cell divisions L Zhuang, KT Lawlor, H Schlueter, Z Pieterse, Y Yu, P Kaur Life science alliance 1 (4), 2018 | 10 | 2018 |
Drosophila Dachsous and Fat polarize actin-based protrusions over a restricted domain of the embryonic denticle field KT Lawlor, DC Ly, S DiNardo Developmental biology 383 (2), 285-294, 2013 | 9 | 2013 |
Cellular extrusion bioprinting improves kidney organoid reproducibility and conformation KT Lawlor, JM Vanslambrouck, JW Higgins, A Chambon, K Bishard, ... Nature Materials, 1-12, 2020 | 3 | 2020 |
Modeling and Analysis of Repeat RNA Toxicity in Drosophila SE Samaraweera, LV O’Keefe, CL van Eyk, KT Lawlor, DT Humphreys, ... Tandem Repeats in Genes, Proteins, and Disease, 173-192, 2013 | 3 | 2013 |
Recreating, expanding and using nephron progenitor populations MH Little, KT Lawlor Nature Reviews Nephrology 16 (2), 75-76, 2020 | | 2020 |