Juan Troncoso
Juan Troncoso
Professor of Pathology, Johns Hopkins University School of Medicine
Verified email at
Cited by
Cited by
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ...
Nature genetics 51 (3), 414-430, 2019
Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature
PT Nelson, I Alafuzoff, EH Bigio, C Bouras, H Braak, NJ Cairns, ...
Journal of Neuropathology & Experimental Neurology 71 (5), 362-381, 2012
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
AC Naj, G Jun, GW Beecham, LS Wang, BN Vardarajan, J Buros, ...
Nature genetics 43 (5), 436-441, 2011
Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease
MJ West, PD Coleman, DG Flood, JC Troncoso
The lancet 344 (8925), 769-772, 1994
Primary age-related tauopathy (PART): a common pathology associated with human aging
JF Crary, JQ Trojanowski, JA Schneider, JF Abisambra, EL Abner, ...
Acta neuropathologica 128, 755-766, 2014
Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity
FC Nucifora Jr, M Sasaki, MF Peters, H Huang, JK Cooper, M Yamada, ...
Science 291 (5512), 2423-2428, 2001
Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease
RG Cutler, J Kelly, K Storie, WA Pedersen, A Tammara, K Hatanpaa, ...
Proceedings of the National Academy of Sciences 101 (7), 2070-2075, 2004
C9orf72 nucleotide repeat structures initiate molecular cascades of disease
AR Haeusler, CJ Donnelly, G Periz, EAJ Simko, PG Shaw, MS Kim, ...
Nature 507 (7491), 195-200, 2014
Endocytic pathway abnormalities precede amyloid β deposition in sporadic Alzheimer’s disease and Down syndrome: differential effects of APOE genotype and presenilin mutations
AM Cataldo, CM Peterhoff, JC Troncoso, T Gomez-Isla, BT Hyman, ...
The American journal of pathology 157 (1), 277-286, 2000
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ...
Nature genetics 49 (9), 1373-1384, 2017
Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain
JR Gibbs, MP Van Der Brug, DG Hernandez, BJ Traynor, MA Nalls, SL Lai, ...
PLoS genetics 6 (5), e1000952, 2010
S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function
KKK Chung, B Thomas, X Li, O Pletnikova, JC Troncoso, L Marsh, ...
Science 304 (5675), 1328-1331, 2004
RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia
T Zu, Y Liu, M Ba˝ez-Coronel, T Reid, O Pletnikova, J Lewis, TM Miller, ...
Proceedings of the National Academy of Sciences 110 (51), E4968-E4977, 2013
Common genetic variants influence human subcortical brain structures
DP Hibar, JL Stein, ME Renteria, A Arias-Vasquez, S DesriviŔres, ...
Nature 520 (7546), 224-229, 2015
Genetic variability in the regulation of gene expression in ten regions of the human brain
A Ramasamy, D Trabzuni, S Guelfi, V Varghese, C Smith, R Walker, T De, ...
Nature neuroscience 17 (10), 1418-1428, 2014
Loss of the presynaptic vesicle protein synaptophysin in hippocampus correlates with cognitive decline in Alzheimer disease
CI Sze, JC Troncoso, C Kawas, P Mouton, DL Price, LJ Martin
Journal of Neuropathology & Experimental Neurology 56 (8), 933-944, 1997
Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation
ECB Johnson, EB Dammer, DM Duong, L Ping, M Zhou, L Yin, ...
Nature medicine 26 (5), 769-780, 2020
Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy
GU H÷glinger, NM Melhem, DW Dickson, PMA Sleiman, LS Wang, L Klei, ...
Nature genetics 43 (7), 699-705, 2011
Gene expression changes in the course of normal brain aging are sexually dimorphic
NC Berchtold, DH Cribbs, PD Coleman, J Rogers, E Head, R Kim, ...
Proceedings of the National Academy of Sciences 105 (40), 15605-15610, 2008
Synphilin-1 associates with α-synuclein and promotes the formation of cytosolic inclusions
S Engelender, Z Kaminsky, X Guo, AH Sharp, RK Amaravi, JJ Kleiderlein, ...
Nature genetics 22 (1), 110-114, 1999
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