| Acidity generated by the tumor microenvironment drives local invasion V Estrella, T Chen, M Lloyd, J Wojtkowiak, HH Cornnell, ... Cancer research 73 (5), 1524-1535, 2013 | 1336 | 2013 |
| pH sensing and regulation in cancer M Damaghi, JW Wojtkowiak, RJ Gillies Frontiers in physiology 4, 70349, 2013 | 591 | 2013 |
| Neutralization of tumor acidity improves antitumor responses to immunotherapy S Pilon-Thomas, KN Kodumudi, AE El-Kenawi, S Russell, AM Weber, ... Cancer research 76 (6), 1381-1390, 2016 | 551 | 2016 |
| Drug resistance and cellular adaptation to tumor acidic pH microenvironment JW Wojtkowiak, D Verduzco, KJ Schramm, RJ Gillies Molecular pharmaceutics 8 (6), 2032-2038, 2011 | 547 | 2011 |
| Imaging pH and metastasis AI Hashim, X Zhang, JW Wojtkowiak, GV Martinez, RJ Gillies NMR in Biomedicine 24 (6), 582-591, 2011 | 298 | 2011 |
| Chronic autophagy is a cellular adaptation to tumor acidic pH microenvironments JW Wojtkowiak, JM Rothberg, V Kumar, KJ Schramm, E Haller, ... Cancer research 72 (16), 3938-3947, 2012 | 256 | 2012 |
| Chronic acidosis in the tumour microenvironment selects for overexpression of LAMP2 in the plasma membrane M Damaghi, NK Tafreshi, MC Lloyd, R Sprung, V Estrella, JW Wojtkowiak, ... Nature communications 6 (1), 8752, 2015 | 182 | 2015 |
| Targeting the metabolic microenvironment of tumors KM Bailey, JW Wojtkowiak, AI Hashim, RJ Gillies Advances in pharmacology 65, 63-107, 2012 | 175 | 2012 |
| A physical sciences network characterization of non-tumorigenic and metastatic cells Scientific reports 3 (1), 1449, 2013 | 170 | 2013 |
| Application of evolutionary principles to cancer therapy PM Enriquez-Navas, JW Wojtkowiak, RA Gatenby Cancer research 75 (22), 4675-4680, 2015 | 167 | 2015 |
| Defining cancer subpopulations by adaptive strategies rather than molecular properties provides novel insights into intratumoral evolution A Ibrahim-Hashim, M Robertson-Tessi, PM Enriquez-Navas, M Damaghi, ... Cancer research 77 (9), 2242-2254, 2017 | 127 | 2017 |
| Acid-mediated tumor proteolysis: contribution of cysteine cathepsins JM Rothberg, KM Bailey, JW Wojtkowiak, Y Ben-Nun, M Bogyo, E Weber, ... Neoplasia 15 (10), 1125-IN9, 2013 | 120 | 2013 |
| The damaging effect of passenger mutations on cancer progression CD McFarland, JA Yaglom, JW Wojtkowiak, JG Scott, DL Morse, ... Cancer research 77 (18), 4763-4772, 2017 | 117 | 2017 |
| Metabolic Profiling of healthy and cancerous tissues in 2D and 3D S Russell, J Wojtkowiak, A Neilson, RJ Gillies Scientific reports 7 (1), 15285, 2017 | 92 | 2017 |
| Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302 JW Wojtkowiak, HC Cornnell, S Matsumoto, K Saito, Y Takakusagi, ... Cancer & metabolism 3, 1-13, 2015 | 79 | 2015 |
| Free base lysine increases survival and reduces metastasis in prostate cancer model A Ibrahim-Hashim, JW Wojtkowiak, MLC Ribeiro, V Estrella, KM Bailey, ... Journal of cancer science & therapy, 2011 | 63 | 2011 |
| A novel geranylgeranyl transferase inhibitor in combination with lovastatin inhibits proliferation and induces autophagy in STS-26T MPNST cells KM Sane, M Mynderse, DT LaLonde, IS Dean, JW Wojtkowiak, F Fouad, ... Journal of Pharmacology and Experimental Therapeutics 333 (1), 23-33, 2010 | 60 | 2010 |
| Induction of apoptosis in neurofibromatosis type 1 malignant peripheral nerve sheath tumor cell lines by a combination of novel farnesyl transferase inhibitors and lovastatin JW Wojtkowiak, F Fouad, DT LaLonde, MD Kleinman, RA Gibbs, ... Journal of Pharmacology and Experimental Therapeutics 326 (1), 1-11, 2008 | 49 | 2008 |
| Molecular targets for emerging anti-tumor therapies for neurofibromatosis type 1 JT Dilworth, JM Kraniak, JW Wojtkowiak, RA Gibbs, RF Borch, MA Tainsky, ... Biochemical pharmacology 72 (11), 1485-1492, 2006 | 49 | 2006 |
| Autophagy on acid JW Wojtkowiak, RJ Gillies Autophagy 8 (11), 1688-1689, 2012 | 44 | 2012 |
Robert GilliesChair of Cancer Physiology, H. Lee Moffitt Cancer CenterVerified email at moffitt.org
