Comprehensive proteomic analysis of mesenchymal stem cell exosomes reveals modulation of angiogenesis via nuclear factor-kappaB signaling JD Anderson, HJ Johansson, CS Graham, M Vesterlund, MT Pham, ... Stem cells 34 (3), 601-613, 2016 | 510 | 2016 |
Human mesenchymal stem cells genetically engineered to overexpress brain-derived neurotrophic factor improve outcomes in Huntington's disease mouse models K Pollock, H Dahlenburg, H Nelson, KD Fink, W Cary, K Hendrix, G Annett, ... Molecular Therapy 24 (5), 965-977, 2016 | 168 | 2016 |
Ezh2-dCas9 and KRAB-dCas9 enable engineering of epigenetic memory in a context-dependent manner H O’Geen, SL Bates, SS Carter, KA Nisson, J Halmai, KD Fink, SK Rhie, ... Epigenetics & chromatin 12, 1-20, 2019 | 137 | 2019 |
Mesenchymal stem cell transplantation and DMEM administration in a 3NP rat model of Huntington's disease: morphological and behavioral outcomes J Rossignol, C Boyer, X Lévèque, KD Fink, R Thinard, F Blanchard, ... Behavioural brain research 217 (2), 369-378, 2011 | 97 | 2011 |
Primed mesenchymal stem cells package exosomes with metabolites associated with immunomodulation MR Showalter, B Wancewicz, O Fiehn, JA Archard, S Clayton, J Wagner, ... Biochemical and biophysical research communications 512 (4), 729-735, 2019 | 83 | 2019 |
Transplants of adult mesenchymal and neural stem cells provide neuroprotection and behavioral sparing in a transgenic rat model of Huntington’s disease J Rossignol, K Fink, K Davis, S Clerc, A Crane, J Matchynski, S Lowrance, ... Stem Cells 32 (2), 500-509, 2014 | 80 | 2014 |
Engineered BDNF producing cells as a potential treatment for neurologic disease P Deng, JD Anderson, AS Yu, G Annett, KD Fink, JA Nolta Expert opinion on biological therapy 16 (8), 1025-1033, 2016 | 61 | 2016 |
Allele-specific reduction of the mutant huntingtin allele using transcription activator-like effectors in human huntington's disease fibroblasts KD Fink, P Deng, J Gutierrez, JS Anderson, A Torrest, A Komarla, ... Cell transplantation 25 (4), 677-686, 2016 | 61 | 2016 |
Clinical trial perspective for adult and juvenile Huntington's disease using genetically-engineered mesenchymal stem cells P Deng, A Torrest, K Pollock, H Dahlenburg, G Annett, JA Nolta, KD Fink Neural regeneration research 11 (5), 702-705, 2016 | 56 | 2016 |
Combining enriched environment and induced pluripotent stem cell therapy results in improved cognitive and motor function following traumatic brain injury J Dunkerson, KE Moritz, J Young, T Pionk, K Fink, J Rossignol, G Dunbar, ... Restorative neurology and neuroscience 32 (5), 675-687, 2014 | 56 | 2014 |
Transplantation of umbilical cord-derived mesenchymal stem cells into the striata of R6/2 mice: behavioral and neuropathological analysis KD Fink, J Rossignol, AT Crane, KK Davis, MC Bombard, AM Bavar, ... Stem Cell Research & Therapy 4, 1-12, 2013 | 52 | 2013 |
Translational outcomes in a full gene deletion of ubiquitin protein ligase E3A rat model of Angelman syndrome EL Berg, MC Pride, SP Petkova, RD Lee, NA Copping, Y Shen, A Adhikari, ... Translational psychiatry 10 (1), 39, 2020 | 49 | 2020 |
Mesenchymal stem cells as treatment for behavioral deficits and neuropathology in the 5xFAD mouse model of Alzheimer's disease JJ Matchynski-Franks, C Pappas, J Rossignol, T Reinke, K Fink, A Crane, ... Cell transplantation 25 (4), 687-703, 2016 | 47 | 2016 |
Exosomes derived from human primed mesenchymal stem cells induce mitosis and potentiate growth factor secretion O Yuan, C Lin, J Wagner, JS Anderson, JA Archard, P Deng, J Halmai, ... Stem cells and development 28 (6), 398-409, 2019 | 44 | 2019 |
Reductions in behavioral deficits and neuropathology in the R6/2 mouse model of Huntington’s disease following transplantation of bone-marrow-derived mesenchymal stem cells is … J Rossignol, KD Fink, AT Crane, KK Davis, MC Bombard, S Clerc, ... Stem cell research & therapy 6, 1-14, 2015 | 44 | 2015 |
Developing stem cell therapies for juvenile and adult-onset Huntington's disease KD Fink, P Deng, A Torrest, H Stewart, K Pollock, W Gruenloh, G Annett, ... Regenerative medicine 10 (5), 623-646, 2015 | 42 | 2015 |
Intrastriatal transplantation of adenovirus-generated induced pluripotent stem cells for treating neuropathological and functional deficits in a rodent model of Huntington's … KD Fink, AT Crane, X Lévêque, DJ Dues, LD Huffman, AC Moore, ... Stem Cells Translational Medicine 3 (5), 620-631, 2014 | 41 | 2014 |
The effects of acute voluntary wheel running on recovery of function following medial frontal cortical contusions in rats AT Crane, KD Fink, JS Smith Restorative neurology and neuroscience 30 (4), 325-333, 2012 | 37 | 2012 |
Artificial escape from XCI by DNA methylation editing of the CDKL5 gene JANM Halmai, P Deng, CE Gonzalez, NB Coggins, D Cameron, JL Carter, ... Nucleic acids research 48 (5), 2372-2387, 2020 | 36 | 2020 |
Survival and differentiation of adenovirus-generated induced pluripotent stem cells transplanted into the rat striatum KD Fink, J Rossignol, M Lu, X Lévêque, TD Hulse, AT Crane, ... Cell transplantation 23 (11), 1407-1423, 2014 | 32 | 2014 |