| Fluorinated amino acids in protein design and engineering NC Yoder, K Kumar Chemical Society Reviews 31 (6), 335-341, 2002 | 367 | 2002 |
| Site-specific N-and C-terminal labeling of a single polypeptide using sortases of different specificity JM Antos, GL Chew, CP Guimaraes, NC Yoder, GM Grotenbreg, ... Journal of the American Chemical Society 131 (31), 10800-10801, 2009 | 285 | 2009 |
| Effects of drug–antibody ratio on pharmacokinetics, biodistribution, efficacy, and tolerability of antibody–maytansinoid conjugates X Sun, JF Ponte, NC Yoder, R Laleau, J Coccia, L Lanieri, Q Qiu, R Wu, ... Bioconjugate Chemistry 28 (5), 1371-1381, 2017 | 206 | 2017 |
| Preparation of unnatural N-to-N and C-to-C protein fusions MD Witte, JJ Cragnolini, SK Dougan, NC Yoder, MW Popp, HL Ploegh Proceedings of the National Academy of Sciences 109 (30), 11993-11998, 2012 | 146 | 2012 |
| A CD123-targeting antibody-drug conjugate, IMGN632, designed to eradicate AML while sparing normal bone marrow cells Y Kovtun, GE Jones, S Adams, L Harvey, CA Audette, A Wilhelm, C Bai, ... Blood advances 2 (8), 848-858, 2018 | 145 | 2018 |
| Understanding how the stability of the thiol-maleimide linkage impacts the pharmacokinetics of lysine-linked antibody–maytansinoid conjugates JF Ponte, X Sun, NC Yoder, N Fishkin, R Laleau, J Coccia, L Lanieri, ... Bioconjugate chemistry 27 (7), 1588-1598, 2016 | 87 | 2016 |
| Bioorthogonal noncovalent chemistry: fluorous phases in chemical biology NC Yoder, D Yüksel, L Dafik, K Kumar Current opinion in chemical biology 10 (6), 576-583, 2006 | 69 | 2006 |
| The chlamydial OTU domain‐containing protein ChlaOTU is an early type III secretion effector targeting ubiquitin and NDP52 AR Furtado, M Essid, S Perrinet, ME Balañá, N Yoder, P Dehoux, A Subtil Cellular microbiology 15 (12), 2064-2079, 2013 | 54 | 2013 |
| A DNA-interacting payload designed to eliminate cross-linking improves the therapeutic index of antibody–drug conjugates (ADCs) ML Miller, M Shizuka, A Wilhelm, P Salomon, EE Reid, L Lanieri, S Sikka, ... Molecular Cancer Therapeutics 17 (3), 650-660, 2018 | 51 | 2018 |
| Discovery and optimization of HKT288, a Cadherin-6–Targeting ADC for the treatment of ovarian and renal cancers CU Bialucha, SD Collins, X Li, P Saxena, X Zhang, C Dürr, B Lafont, ... Cancer discovery 7 (9), 1030-1045, 2017 | 50 | 2017 |
| Catch‐and‐Release Probes Applied to Semi‐Intact Cells Reveal Ubiquitin‐Specific Protease Expression in Chlamydia trachomatis Infection JHL Claessen, MD Witte, NC Yoder, AY Zhu, E Spooner, HL Ploegh Chembiochem 14 (3), 343-352, 2013 | 44 | 2013 |
| Nanoscale Patterning in Mixed Fluorocarbon− Hydrocarbon Phospholipid Bilayers NC Yoder, V Kalsani, S Schuy, R Vogel, A Janshoff, K Kumar Journal of the American Chemical Society 129 (29), 9037-9043, 2007 | 41 | 2007 |
| Using sortases to install click chemistry handles for protein ligation HL Ploegh, MD Witte, NC Yoder US Patent 10,081,684, 2018 | 40 | 2018 |
| Structure and thermotropic phase behavior of fluorinated phospholipid bilayers: a combined attenuated total reflection FTIR spectroscopy and imaging ellipsometry study S Schuy, S Faiss, NC Yoder, V Kalsani, K Kumar, A Janshoff, R Vogel The Journal of Physical Chemistry B 112 (28), 8250-8256, 2008 | 39 | 2008 |
| Use of fungal derived polysaccharide-conjugated particles to probe Dectin-1 responses in innate immunity JM Tam, MK Mansour, NS Khan, NC Yoder, JM Vyas Integrative biology 4 (2), 220-227, 2012 | 37 | 2012 |
| A case study comparing heterogeneous lysine-and site-specific cysteine-conjugated maytansinoid antibody-drug conjugates (ADCs) illustrates the benefits of lysine conjugation NC Yoder, C Bai, D Tavares, WC Widdison, KR Whiteman, A Wilhelm, ... Molecular Pharmaceutics 16 (9), 3926-3937, 2019 | 30 | 2019 |
| Site-specific conjugation of the indolinobenzodiazepine DGN549 to antibodies affords antibody–drug conjugates with an improved therapeutic index as compared with lysine conjugation C Bai, EE Reid, A Wilhelm, M Shizuka, EK Maloney, R Laleau, L Harvey, ... Bioconjugate Chemistry 31 (1), 93-103, 2019 | 26 | 2019 |
| Selective Protein− Protein Interactions Driven by a Phenylalanine Interface NC Yoder, K Kumar Journal of the American Chemical Society 128 (1), 188-191, 2006 | 26 | 2006 |
| Microscale screening of antibody libraries as maytansinoid antibody-drug conjugates KC Catcott, MA McShea, CU Bialucha, KL Miller, SW Hicks, P Saxena, ... MAbs 8 (3), 513-523, 2016 | 20 | 2016 |
| Using sortases to install click chemistry handles for protein ligation HL Ploegh, MD Witte, NC Yoder US Patent 11,028,185, 2021 | 15 | 2021 |
