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Maxime W Rousseaux
Maxime W Rousseaux
University of Ottawa Brain and Mind Research Institute
Verified email at uottawa.ca - Homepage
Title
Cited by
Cited by
Year
Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics
I Irrcher, H Aleyasin, EL Seifert, SJ Hewitt, S Chhabra, M Phillips, AK Lutz, ...
Human molecular genetics 19 (19), 3734-3746, 2010
4582010
Role of Cdk5-mediated phosphorylation of Prx2 in MPTP toxicity and Parkinson's disease
D Qu, J Rashidian*, MP Mount*, H Aleyasin*, M Parsanejad, A Lira, ...
Neuron 55 (1), 37-52, 2007
2812007
The role of TDP-43 mislocalization in amyotrophic lateral sclerosis
TR Suk, MWC Rousseaux
Molecular neurodegeneration 15 (1), 45, 2020
2642020
DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway
H Aleyasin*, MWC Rousseaux*, PC Marcogliese, SJ Hewitt, I Irrcher, ...
Proceedings of the National Academy of Sciences, 200914876, 2010
1992010
The Parkinson's disease gene DJ-1 is also a key regulator of stroke-induced damage
H Aleyasin, MWC Rousseaux, M Phillips, RH Kim, RJ Bland, S Callaghan, ...
Proceedings of the National Academy of Sciences 104 (47), 18748-18753, 2007
1862007
Reduction of Nuak1 decreases tau and reverses phenotypes in a tauopathy mouse model
CA Lasagna-Reeves, M de Haro, S Hao, J Park, MWC Rousseaux, ...
Neuron 92 (2), 407-418, 2016
1472016
Disruption of the ATXN1–CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans
HC Lu*, Q Tan*, MWC Rousseaux, W Wang, JY Kim, R Richman, ...
Nature genetics 49 (4), 527, 2017
1352017
The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death
E Huang*, D Qu*, Y Zhang, K Venderova, ME Haque, MWC Rousseaux, ...
Nature cell biology 12 (6), 563, 2010
1282010
TRIM28 regulates the nuclear accumulation and toxicity of both alpha-synuclein and tau
MWC Rousseaux, M de Haro, CA Lasagna-Reeves, A De Maio, J Park, ...
elife 5, e19809, 2016
1102016
ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism
MWC Rousseaux*, T Tschumperlin*, HC Lu*, EP Lackey, VV Bondar, ...
Neuron 97 (6), 1235-1243. e5, 2018
1082018
Progressive dopaminergic cell loss with unilateral-to-bilateral progression in a genetic model of Parkinson disease
MWC Rousseaux, PC Marcogliese, D Qu, SJ Hewitt, S Seang, RH Kim, ...
Proceedings of the National Academy of Sciences 109 (39), 15918-15923, 2012
1012012
Essential role of cytoplasmic cdk5 and Prx2 in multiple ischemic injury models, in vivo
J Rashidian, MW Rousseaux, K Venderova, D Qu, SM Callaghan, ...
Journal of Neuroscience 29 (40), 12497-12505, 2009
882009
An anatomically resolved mouse brain proteome reveals parkinson disease-relevant pathways
SY Jung*, JM Choi*, MWC Rousseaux*, A Malovannaya, JJ Kim, ...
Molecular & Cellular Proteomics, mcp. M116. 061440, 2017
612017
BAG2 gene-mediated regulation of PINK1 protein is critical for mitochondrial translocation of PARKIN and neuronal survival
D Qu, A Hage, K Don-Carolis, E Huang, A Joselin, F Safarpour, ...
Journal of Biological Chemistry 290 (51), 30441-30452, 2015
602015
DJ-1 interacts with and regulates paraoxonase-2, an enzyme critical for neuronal survival in response to oxidative stress
M Parsanejad, N Bourquard, D Qu, Y Zhang, E Huang, MWC Rousseaux, ...
PLoS One 9 (9), e106601, 2014
522014
Regulation of the VHL/HIF-1 pathway by DJ-1
M Parsanejad, Y Zhang, D Qu, I Irrcher, MWC Rousseaux, H Aleyasin, ...
Journal of Neuroscience 34 (23), 8043-8050, 2014
512014
Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma
Q Tan, L Brunetti, MWC Rousseaux, HC Lu, YW Wan, JP Revelli, Z Liu, ...
Proceedings of the National Academy of Sciences 115 (7), E1511-E1519, 2018
502018
A druggable genome screen identifies modifiers of α-synuclein levels via a tiered cross-species validation approach
MWC Rousseaux*, GE Vázquez-Vélez*, I Al-Ramahi, HH Jeong, A Bajić, ...
Journal of Neuroscience 38 (43), 9286-9301, 2018
492018
Depleting Trim28 in adult mice is well tolerated and reduces levels of α-synuclein and tau
MWC Rousseaux, JP Revelli, GE Vázquez-Vélez, JY Kim, E Craigen, ...
Elife 7, e36768, 2018
482018
Beta-binomial modeling of CRISPR pooled screen data identifies target genes with greater sensitivity and fewer false negatives
HH Jeong, SY Kim, MWC Rousseaux, HY Zoghbi, Z Liu
Genome research 29 (6), 999-1008, 2019
422019
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