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Lye T. Lock
Lye T. Lock
Department of Chemical & Biological Engineering, State University of New York at Buffalo
Verified email at buffalo.edu - Homepage
Title
Cited by
Cited by
Year
Scalable stirred-suspension bioreactor culture of human pluripotent stem cells
DE Kehoe, D Jing, LT Lock, ES Tzanakakis
Tissue Engineering Part A 16 (2), 405-421, 2010
3412010
Expansion and differentiation of human embryonic stem cells to endoderm progeny in a microcarrier stirred-suspension culture
LT Lock, ES Tzanakakis
Tissue Engineering Part A 15 (8), 2051-2063, 2009
2272009
Stem/progenitor cell sources of insulin-producing cells for the treatment of diabetes
LT Lock, ES Tzanakakis
Tissue engineering 13 (7), 1399-1412, 2007
1132007
Standardized biosynthesis of flavan-3-ols with effects on pancreatic beta-cell insulin secretion
JA Chemler, LT Lock, MAG Koffas, ES Tzanakakis
Applied microbiology and biotechnology 77, 797-807, 2007
972007
Peak MSC—are we there yet?
TR Olsen, KS Ng, LT Lock, T Ahsan, JA Rowley
Frontiers in medicine 5, 178, 2018
912018
Downstream technology landscape for large-scale therapeutic cell processing
J Pattasseril, H Varadaraju, L Lock, JA Rowley
Bioprocess Int 11 (3), 38-47, 2013
632013
Propagation of embryonic stem cells in stirred suspension without serum
DE Kehoe, LT Lock, A Parikh, ES Tzanakakis
Biotechnology progress 24 (6), 1342-1352, 2008
622008
Pseudoislets in stirred-suspension culture exhibit enhanced cell survival, propagation and insulin secretion
LT Lock, SG Laychock, ES Tzanakakis
Journal of biotechnology 151 (3), 278-286, 2011
402011
Bioreactor parameters for microcarrier-based human MSC expansion under xeno-free conditions in a vertical-wheel system
J Lembong, R Kirian, JD Takacs, TR Olsen, LT Lock, JA Rowley, T Ahsan
Bioengineering 7 (3), 73, 2020
392020
Ready-to-print cells and integrated devices
JA Rowley, LT Lock
US Patent 11,058,106, 2021
122021
Scalable process for therapeutic cell concentration and residual clearance
J Rowley, J Pattasseril, LT Lock
US Patent 10,385,307, 2019
82019
Cryopreserved hMSCs maintain comparable in vitro functional activity compared to fresh hMSCs
I Farance, LT Lock, P Baraniak, JA Rowley
Cytotherapy 17 (6), S67-S68, 2015
42015
Scalable production of pancreatic islet progenitors for diabetes cell therapies.
LT Lock, ES Tzanakakis
The Medical Journal of Malaysia 63, 5-6, 2008
42008
Scaling up: how manufacturing sciences will dictate the future of cell therapy
TR Olsen, LT Lock, JA Rowley
REGENERATIVE MEDICINE 11 (8), S15-S18, 2016
32016
The effect of cryomedia selection and transient warming events on post-cryopreservation human MSC function
BJ Hawkins, A Abazari, LT Lock, T Ahsan, JA Rowley, J Fink, AJ Mathew
Cytotherapy 20 (5), S40, 2018
22018
Rapid and economic generation of consistent hMSC spheroids for macroscopic tissue biofabrication and therapeutic applications
LT Lock, I Farance, P Baraniak, AC Tsai, T Ma, JA Rowley
Cytotherapy 17 (6), S77, 2015
22015
A xeno-free fed-batch microcarrier suspension bioreactor system for the scalable and economic expansion of hBM-MSCs
TR Olsen, R Kirian, L Lock, JA Rowley
Cytotherapy 20 (5), S48, 2018
12018
Rapid and robust large-scale expansion of high quality human mesenchymal stem cells for use in regenerative medicine applications
D Splan, L Lock, JA Rowley, MS Szczypka
Cytotherapy 19 (5), S146, 2017
12017
Derivation of heart cell progeny from human pluripotent stem cells
D Jing, LT Lock, ES Tzanakakis
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 239, 2010
12010
Methods and compositions related to extracellular material derived from hypertonic cell solutions
JA Rowley, LT Lock, P RAVISHANKAR
US Patent App. 17/055,276, 2021
2021
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