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Fayal Abderemane-Ali, PhD
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Structure of a prokaryotic sodium channel pore reveals essential gating elements and an outer ion binding site common to eukaryotic channels
D Shaya, F Findeisen, F Abderemane-Ali, C Arrigoni, S Wong, SR Nurva, ...
Journal of molecular biology 426 (2), 467-483, 2014
1582014
A calmodulin C-lobe Ca2+-dependent switch governs Kv7 channel function
A Chang, F Abderemane-Ali, GL Hura, ND Rossen, RE Gate, DL Minor
Neuron 97 (4), 836-852. e6, 2018
742018
KCNQ1 channels voltage dependence through a voltage-dependent binding of the S4-S5 linker to the pore domain
FS Choveau, N Rodriguez, FA Ali, AJ Labro, T Rose, S Dahimène, ...
Journal of biological chemistry 286 (1), 707-716, 2011
632011
K2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions
M Lolicato, AM Natale, F Abderemane-Ali, D Crottès, S Capponi, ...
Science advances 6 (44), eabc9174, 2020
622020
A selectivity filter gate controls voltage-gated calcium channel calcium-dependent inactivation
F Abderemane-Ali, F Findeisen, ND Rossen, DL Minor
Neuron 101 (6), 1134-1149. e3, 2019
472019
Dual effect of phosphatidyl (4, 5)-bisphosphate PIP2 on Shaker K+ channels
F Abderemane-Ali, Z Es-Salah-Lamoureux, L Delemotte, MA Kasimova, ...
Journal of biological chemistry 287 (43), 36158-36167, 2012
462012
Stapled Voltage-Gated Calcium Channel (CaV) α-Interaction Domain (AID) Peptides Act As Selective Protein–Protein Interaction Inhibitors of CaV Function
F Findeisen, M Campiglio, H Jo, F Abderemane-Ali, CH Rumpf, L Pope, ...
ACS chemical neuroscience 8 (6), 1313-1326, 2017
412017
Opposite Effects of the S4–S5 Linker and PIP2 on Voltage-Gated Channel Function: KCNQ1/KCNE1 and Other Channels
FS Choveau, F Abderemane-Ali, FC Coyan, Z Es-Salah-Lamoureux, ...
Frontiers in pharmacology 3, 125, 2012
392012
A long QT mutation substitutes cholesterol for phosphatidylinositol-4, 5-bisphosphate in KCNQ1 channel regulation
FC Coyan, F Abderemane-Ali, MY Amarouch, J Piron, J Mordel, ...
PLoS One 9 (3), e93255, 2014
272014
Evidence that toxin resistance in poison birds and frogs is not rooted in sodium channel mutations and may rely on “toxin sponge” proteins
F Abderemane-Ali, ND Rossen, ME Kobiela, RA Craig, CE Garrison, ...
Journal of General Physiology 153 (9), e202112872, 2021
262021
EMC chaperone–CaV structure reveals an ion channel assembly intermediate
Z Chen, A Mondal, F Abderemane-Ali, S Jang, S Niranjan, JL Montaño, ...
Nature 619 (7969), 410-419, 2023
152023
Differential effects of modified batrachotoxins on voltage-gated sodium channel fast and slow inactivation
TMG MacKenzie, F Abderemane-Ali, CE Garrison, DL Minor, J Du Bois
Cell chemical biology 29 (4), 615-624. e5, 2022
62022
Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family
Z Chen, S Zakrzewska, HS Hajare, A Alvarez-Buylla, F Abderemane-Ali, ...
Proceedings of the National Academy of Sciences 119 (44), e2210114119, 2022
42022
Up-regulation of voltage-gated sodium channels by peptides mimicking S4-S5 linkers reveals a variation of the ligand-receptor mechanism
OA Malak, F Abderemane-Ali, Y Wei, FC Coyan, G Pontus, D Shaya, ...
Scientific Reports 10 (1), 5852, 2020
42020
EMC holdase:CaV1.2/CaVβ3 complex and CaV1.2 channel structures reveal CaV assembly and drug binding mechanisms
Z Chen, A Mondal, F Abderemane-Ali, J Montano, B Zaro, DL Minor Jr
bioRxiv, 2022.10. 03.510667, 2022
32022
Dual effect of phosphatidylinositol (4, 5)-bisphosphate PIP2 on Shaker K+ channels.
F Abderemane-Ali, Z Es-Salah-Lamoureux, L Delemotte, MA Kasimova, ...
The Journal of Biological Chemistry 288 (15), 10951, 2013
22013
Opposite effects of the S4-S5 linker and PIP (2) on voltage-gated channel function: KCNQ1/KCNE1 and other channels. Front Pharmacol 3: 125
FS Choveau, F Abderemane-Ali, FC Coyan, Z Es-Salah-Lamoureux, ...
22012
K2PChannel C-Type Gating Involves Asymmetric Selectivity Filter Order-Disorder Transitions
AM Natale, MGL Lolicato, F Abderemane-Ali, D Crottès, S Capponi, ...
Biophysical Journal 120 (3), 111a-112a, 2021
12021
Sodium channel toxin-resistance mutations do not govern batrachotoxin (BTX) autoresistance in poison birds and frogs
F Abderemane-Ali, ND Rossen, ME Kobiela, RA Craig, CE Garrison, ...
bioRxiv, 2020.10. 29.361212, 2020
12020
Structure of an EMC chaperone: CaV complex reveals an ion channel assembly intermediate and a holdase function for the EMC
Z Chen, A Mondal, F Abderemane-Ali, S Jang, S Niranjan, JL Montaño, ...
Biophysical Journal 123 (3), 14a, 2024
2024
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Articles 1–20