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Jan Passchier
Jan Passchier
Director of Operations and Head of Preclinical Sciences, Imanova Ltd
Verified email at imanova.co.uk - Homepage
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Cited by
Year
A General Copper‐Mediated Nucleophilic 18F Fluorination of Arenes
M Tredwell, SM Preshlock, NJ Taylor, S Gruber, M Huiban, J Passchier, ...
Angewandte Chemie International Edition 53 (30), 7751-7755, 2014
4152014
Positron emission tomography molecular imaging for drug development
PM Matthews, EA Rabiner, J Passchier, RN Gunn
British journal of clinical pharmacology 73 (2), 175-186, 2012
3482012
A broadly applicable [18F]trifluoromethylation of aryl and heteroaryl iodides for PET imaging
M Huiban, M Tredwell, S Mizuta, Z Wan, X Zhang, TL Collier, ...
Nature chemistry 5 (11), 941-944, 2013
2002013
Catalytic decarboxylative fluorination for the synthesis of tri-and difluoromethyl arenes
S Mizuta, ISR Stenhagen, M O’Duill, J Wolstenhulme, AK Kirjavainen, ...
Organic letters 15 (11), 2648-2651, 2013
1992013
Enhanced copper-mediated 18 F-fluorination of aryl boronic esters provides eight radiotracers for PET applications
S Preshlock, S Calderwood, S Verhoog, M Tredwell, M Huiban, ...
Chemical communications 52 (54), 8361-8364, 2016
1742016
Rapid Multiphase Carbonylation Reactions by Using a Microtube Reactor: Applications in Positron Emission Tomography 11C‐Radiolabeling
PW Miller, NJ Long, AJ de Mello, R Vilar, H Audrain, D Bender, ...
Angewandte Chemie International Edition 46 (16), 2875-2878, 2007
1442007
Determination of [11C]PBR28 Binding Potential in vivo: A First Human TSPO Blocking Study
DR Owen, Q Guo, NJ Kalk, A Colasanti, D Kalogiannopoulou, R Dimber, ...
Journal of Cerebral Blood Flow & Metabolism 34 (6), 989-994, 2014
1412014
Visualisation of serotonin-1A (5-HT1A) receptors in the central nervous system
J Passchier, A van Waarde
European journal of nuclear medicine 28, 113-129, 2001
1292001
Metal‐Free Oxidative Fluorination of Phenols with [18F]Fluoride
Z Gao, YH Lim, M Tredwell, L Li, S Verhoog, M Hopkinson, W Kaluza, ...
Angewandte Chemie International Edition 51 (27), 6733-6737, 2012
1162012
Toward an improved prediction of human in vivo brain penetration
SG Summerfield, AJ Lucas, RA Porter, P Jeffrey, RN Gunn, KR Read, ...
Xenobiotica 38 (12), 1518-1535, 2008
1132008
[18 F] Fluorination of an arylboronic ester using [18 F] selectfluor bis (triflate): application to 6-[18 F] fluoro-l-DOPA
ISR Stenhagen, AK Kirjavainen, SJ Forsback, CG Jørgensen, EG Robins, ...
Chemical Communications 49 (14), 1386-1388, 2013
1112013
Pharmacological differentiation of opioid receptor antagonists by molecular and functional imaging of target occupancy and food reward-related brain activation in humans
EA Rabiner, J Beaver, A Makwana, G Searle, C Long, PJ Nathan, ...
Molecular psychiatry 16 (8), 826-835, 2011
1102011
Pharmacological differentiation of opioid receptor antagonists by molecular and functional imaging of target occupancy and food reward-related brain activation in humans
EA Rabiner, J Beaver, A Makwana, G Searle, C Long, PJ Nathan, ...
Molecular psychiatry 16 (8), 826-835, 2011
1052011
In vivo imaging of microglial activation by positron emission tomography with [11C]PBR28 in the 5XFAD model of Alzheimer's disease
N Mirzaei, SP Tang, S Ashworth, C Coello, C Plisson, J Passchier, ...
Glia 64 (6), 993-1006, 2016
922016
A comparison of the behavior of 64Cu-acetate and 64Cu-ATSM in vitro and in vivo
R Hueting, V Kersemans, B Cornelissen, M Tredwell, K Hussien, ...
Journal of Nuclear Medicine 55 (1), 128-134, 2014
812014
Measuring drug-related receptor occupancy with positron emission tomography
J Passchier, A Gee, A Willemsen, W Vaalburg, A van Waarde
Methods 27 (3), 278-286, 2002
802002
Rapid formation of amides via carbonylative coupling reactions using a microfluidic device
PW Miller, NJ Long, AJ de Mello, R Vilar, J Passchier, A Gee
Chemical communications, 546-548, 2006
742006
Influence of P-glycoprotein on brain uptake of [18F] MPPF in rats
J Passchier, A van Waarde, P Doze, PH Elsinga, W Vaalburg
European journal of pharmacology 407 (3), 273-280, 2000
742000
In vivo delineation of 5-HT1A receptors in human brain with [18F] MPPF
J Passchier, A van Waarde, RM Pieterman, PH Elsinga, J Pruim, ...
Journal of Nuclear Medicine 41 (11), 1830-1835, 2000
722000
In vivo detection of cerebral tau pathology in long-term survivors of traumatic brain injury
N Gorgoraptis, LM Li, A Whittington, KA Zimmerman, LM Maclean, ...
Science Translational Medicine 11 (508), eaaw1993, 2019
712019
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