A General Copper‐Mediated Nucleophilic 18F Fluorination of Arenes M Tredwell, SM Preshlock, NJ Taylor, S Gruber, M Huiban, J Passchier, ... Angewandte Chemie International Edition 53 (30), 7751-7755, 2014 | 415 | 2014 |
Positron emission tomography molecular imaging for drug development PM Matthews, EA Rabiner, J Passchier, RN Gunn British journal of clinical pharmacology 73 (2), 175-186, 2012 | 348 | 2012 |
A broadly applicable [18F]trifluoromethylation of aryl and heteroaryl iodides for PET imaging M Huiban, M Tredwell, S Mizuta, Z Wan, X Zhang, TL Collier, ... Nature chemistry 5 (11), 941-944, 2013 | 200 | 2013 |
Catalytic decarboxylative fluorination for the synthesis of tri-and difluoromethyl arenes S Mizuta, ISR Stenhagen, M O’Duill, J Wolstenhulme, AK Kirjavainen, ... Organic letters 15 (11), 2648-2651, 2013 | 199 | 2013 |
Enhanced copper-mediated 18 F-fluorination of aryl boronic esters provides eight radiotracers for PET applications S Preshlock, S Calderwood, S Verhoog, M Tredwell, M Huiban, ... Chemical communications 52 (54), 8361-8364, 2016 | 174 | 2016 |
Rapid Multiphase Carbonylation Reactions by Using a Microtube Reactor: Applications in Positron Emission Tomography 11C‐Radiolabeling PW Miller, NJ Long, AJ de Mello, R Vilar, H Audrain, D Bender, ... Angewandte Chemie International Edition 46 (16), 2875-2878, 2007 | 144 | 2007 |
Determination of [11C]PBR28 Binding Potential in vivo: A First Human TSPO Blocking Study DR Owen, Q Guo, NJ Kalk, A Colasanti, D Kalogiannopoulou, R Dimber, ... Journal of Cerebral Blood Flow & Metabolism 34 (6), 989-994, 2014 | 141 | 2014 |
Visualisation of serotonin-1A (5-HT1A) receptors in the central nervous system J Passchier, A van Waarde European journal of nuclear medicine 28, 113-129, 2001 | 129 | 2001 |
Metal‐Free Oxidative Fluorination of Phenols with [18F]Fluoride Z Gao, YH Lim, M Tredwell, L Li, S Verhoog, M Hopkinson, W Kaluza, ... Angewandte Chemie International Edition 51 (27), 6733-6737, 2012 | 116 | 2012 |
Toward an improved prediction of human in vivo brain penetration SG Summerfield, AJ Lucas, RA Porter, P Jeffrey, RN Gunn, KR Read, ... Xenobiotica 38 (12), 1518-1535, 2008 | 113 | 2008 |
[18 F] Fluorination of an arylboronic ester using [18 F] selectfluor bis (triflate): application to 6-[18 F] fluoro-l-DOPA ISR Stenhagen, AK Kirjavainen, SJ Forsback, CG Jørgensen, EG Robins, ... Chemical Communications 49 (14), 1386-1388, 2013 | 111 | 2013 |
Pharmacological differentiation of opioid receptor antagonists by molecular and functional imaging of target occupancy and food reward-related brain activation in humans EA Rabiner, J Beaver, A Makwana, G Searle, C Long, PJ Nathan, ... Molecular psychiatry 16 (8), 826-835, 2011 | 110 | 2011 |
Pharmacological differentiation of opioid receptor antagonists by molecular and functional imaging of target occupancy and food reward-related brain activation in humans EA Rabiner, J Beaver, A Makwana, G Searle, C Long, PJ Nathan, ... Molecular psychiatry 16 (8), 826-835, 2011 | 105 | 2011 |
In vivo imaging of microglial activation by positron emission tomography with [11C]PBR28 in the 5XFAD model of Alzheimer's disease N Mirzaei, SP Tang, S Ashworth, C Coello, C Plisson, J Passchier, ... Glia 64 (6), 993-1006, 2016 | 92 | 2016 |
A comparison of the behavior of 64Cu-acetate and 64Cu-ATSM in vitro and in vivo R Hueting, V Kersemans, B Cornelissen, M Tredwell, K Hussien, ... Journal of Nuclear Medicine 55 (1), 128-134, 2014 | 81 | 2014 |
Measuring drug-related receptor occupancy with positron emission tomography J Passchier, A Gee, A Willemsen, W Vaalburg, A van Waarde Methods 27 (3), 278-286, 2002 | 80 | 2002 |
Rapid formation of amides via carbonylative coupling reactions using a microfluidic device PW Miller, NJ Long, AJ de Mello, R Vilar, J Passchier, A Gee Chemical communications, 546-548, 2006 | 74 | 2006 |
Influence of P-glycoprotein on brain uptake of [18F] MPPF in rats J Passchier, A van Waarde, P Doze, PH Elsinga, W Vaalburg European journal of pharmacology 407 (3), 273-280, 2000 | 74 | 2000 |
In vivo delineation of 5-HT1A receptors in human brain with [18F] MPPF J Passchier, A van Waarde, RM Pieterman, PH Elsinga, J Pruim, ... Journal of Nuclear Medicine 41 (11), 1830-1835, 2000 | 72 | 2000 |
In vivo detection of cerebral tau pathology in long-term survivors of traumatic brain injury N Gorgoraptis, LM Li, A Whittington, KA Zimmerman, LM Maclean, ... Science Translational Medicine 11 (508), eaaw1993, 2019 | 71 | 2019 |