Cationic pillararenes potently inhibit biofilm formation without affecting bacterial growth and viability R Joseph, A Naugolny, M Feldman, IM Herzog, M Fridman, Y Cohen Journal of the American Chemical Society 138 (3), 754-757, 2016 | 209 | 2016 |
Bacterial-derived exopolysaccharides enhance antifungal drug tolerance in a cross-kingdom oral biofilm D Kim, Y Liu, RI Benhamou, H Sanchez, Á Simón-Soro, Y Li, G Hwang, ... The ISME Journal 12 (6), 1427-1442, 2018 | 134 | 2018 |
6′′‐Thioether tobramycin analogues: towards selective targeting of bacterial membranes IM Herzog, KD Green, Y Berkov‐Zrihen, M Feldman, RR Vidavski, ... Angewandte Chemie 124 (23), 5750-5754, 2012 | 100 | 2012 |
The relationship between the structure and toxicity of aminoglycoside antibiotics M Jospe-Kaufman, L Siomin, M Fridman Bioorganic & medicinal chemistry letters 30 (13), 127218, 2020 | 99 | 2020 |
Dual Effect of Synthetic Aminoglycosides: Antibacterial Activity against Bacillus anthracis and Inhibition of Anthrax Lethal Factor M Fridman, V Belakhov, LV Lee, FS Liang, CH Wong, T Baasov Angewandte Chemie International Edition 44 (3), 447-452, 2005 | 93 | 2005 |
Exploring the substrate promiscuity of drug‐modifying enzymes for the chemoenzymatic generation of N‐acylated aminoglycosides KD Green, W Chen, JL Houghton, M Fridman, S Garneau‐Tsodikova ChemBioChem 11 (1), 119-126, 2010 | 89 | 2010 |
A new class of branched aminoglycosides: pseudo-pentasaccharide derivatives of neomycin B M Fridman, V Belakhov, S Yaron, T Baasov Organic letters 5 (20), 3575-3578, 2003 | 86 | 2003 |
Design and synthesis of membrane-targeting antibiotics: from peptides-to aminosugar-based antimicrobial cationic amphiphiles IM Herzog, M Fridman MedChemComm 5 (8), 1014-1026, 2014 | 81 | 2014 |
One-pot synthesis of glucosamine oligosaccharides M Fridman, D Solomon, S Yogev, T Baasov Organic Letters 4 (2), 281-283, 2002 | 80 | 2002 |
Inhibition of glioma progression by a newly discovered CD38 inhibitor E Blacher, B Ben Baruch, A Levy, N Geva, KD Green, ... International journal of cancer 136 (6), 1422-1433, 2015 | 78 | 2015 |
Structural insights of lincosamides targeting the ribosome of Staphylococcus aureus D Matzov, Z Eyal, RI Benhamou, M Shalev-Benami, Y Halfon, M Krupkin, ... Nucleic acids research 45 (17), 10284-10292, 2017 | 76 | 2017 |
Mechanisms of resistance to membrane-disrupting antibiotics in Gram-positive and Gram-negative bacteria KB Steinbuch, M Fridman MedChemComm 7 (1), 86-102, 2016 | 74 | 2016 |
Real-time imaging of the azole class of antifungal drugs in live Candida cells RI Benhamou, M Bibi, KB Steinbuch, H Engel, M Levin, Y Roichman, ... ACS chemical biology 12 (7), 1769-1777, 2017 | 72 | 2017 |
Antifungal activity, mode of action variability, and subcellular distribution of coumarin-based antifungal azoles R Elias, RI Benhamou, QZ Jaber, O Dorot, SL Zada, K Oved, E Pichinuk, ... European journal of medicinal chemistry 179, 779-790, 2019 | 64 | 2019 |
Branched aminoglycosides: Biochemical studies and antibacterial activity of neomycin B derivatives M Hainrichson, V Pokrovskaya, D Shallom-Shezifi, M Fridman, ... Bioorganic & medicinal chemistry 13 (20), 5797-5807, 2005 | 60 | 2005 |
Phosphonium pillar [5] arenes as a new class of efficient biofilm inhibitors: importance of charge cooperativity and the pillar platform R Joseph, D Kaizerman, IM Herzog, M Hadar, M Feldman, M Fridman, ... Chemical Communications 52 (70), 10656-10659, 2016 | 55 | 2016 |
Di‐N‐Methylation of Anti‐Gram‐Positive Aminoglycoside‐Derived Membrane Disruptors Improves Antimicrobial Potency and Broadens Spectrum to Gram … RI Benhamou, P Shaul, IM Herzog, M Fridman Angewandte Chemie 127 (46), 13821-13825, 2015 | 54 | 2015 |
Guiding drugs to target‐harboring organelles: Stretching drug‐delivery to a higher level of resolution S Louzoun‐Zada, QZ Jaber, M Fridman Angewandte Chemie 131 (44), 15730-15740, 2019 | 52 | 2019 |
Antimycobacterial activity of DNA intercalator inhibitors of Mycobacterium tuberculosis primase DnaG C Gajadeera, MJ Willby, KD Green, P Shaul, M Fridman, ... The Journal of antibiotics 68 (3), 153-157, 2015 | 48 | 2015 |
Characterization of non-dialyzable constituents from cranberry juice that inhibit adhesion, co-aggregation and biofilm formation by oral bacteria CC Neto, KA Penndorf, M Feldman, S Meron-Sudai, Z Zakay-Rones, ... Food & function 8 (5), 1955-1965, 2017 | 46 | 2017 |