Micha Fridman
Micha Fridman
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Cationic pillararenes potently inhibit biofilm formation without affecting bacterial growth and viability
R Joseph, A Naugolny, M Feldman, IM Herzog, M Fridman, Y Cohen
Journal of the American Chemical Society 138 (3), 754-757, 2016
Dual Effect of Synthetic Aminoglycosides: Antibacterial Activity against Bacillus anthracis and Inhibition of Anthrax Lethal Factor
M Fridman, V Belakhov, LV Lee, FS Liang, CH Wong, T Baasov
Angewandte Chemie International Edition 44 (3), 447-452, 2005
6′′‐Thioether Tobramycin Analogues: Towards Selective Targeting of Bacterial Membranes
IM Herzog, KD Green, Y Berkov‐Zrihen, M Feldman, RR Vidavski, ...
Angewandte Chemie 124 (23), 5750-5754, 2012
Exploring the substrate promiscuity of drug‐modifying enzymes for the chemoenzymatic generation of N‐acylated aminoglycosides
KD Green, W Chen, JL Houghton, M Fridman, S Garneau‐Tsodikova
ChemBioChem 11 (1), 119-126, 2010
Bacterial-derived exopolysaccharides enhance antifungal drug tolerance in a cross-kingdom oral biofilm
D Kim, Y Liu, RI Benhamou, H Sanchez, Á Simón-Soro, Y Li, G Hwang, ...
The ISME journal 12 (6), 1427-1442, 2018
A new class of branched aminoglycosides: pseudo-pentasaccharide derivatives of neomycin B
M Fridman, V Belakhov, S Yaron, T Baasov
Organic letters 5 (20), 3575-3578, 2003
One-pot synthesis of glucosamine oligosaccharides
M Fridman, D Solomon, S Yogev, T Baasov
Organic Letters 4 (2), 281-283, 2002
Design and synthesis of membrane-targeting antibiotics: from peptides-to aminosugar-based antimicrobial cationic amphiphiles
IM Herzog, M Fridman
MedChemComm 5 (8), 1014-1026, 2014
Inhibition of glioma progression by a newly discovered CD38 inhibitor
E Blacher, B Ben Baruch, A Levy, N Geva, KD Green, ...
International Journal of Cancer 136 (6), 1422-1433, 2015
Branched aminoglycosides: Biochemical studies and antibacterial activity of neomycin B derivatives
M Hainrichson, V Pokrovskaya, D Shallom-Shezifi, M Fridman, ...
Bioorganic & medicinal chemistry 13 (20), 5797-5807, 2005
Mechanisms of resistance to membrane-disrupting antibiotics in Gram-positive and Gram-negative bacteria
KB Steinbuch, M Fridman
MedChemComm 7 (1), 86-102, 2016
Real-time imaging of the azole class of antifungal drugs in live Candida cells
RI Benhamou, M Bibi, KB Steinbuch, H Engel, M Levin, Y Roichman, ...
ACS chemical biology 12 (7), 1769-1777, 2017
Structural insights of lincosamides targeting the ribosome of Staphylococcus aureus
D Matzov, Z Eyal, RI Benhamou, M Shalev-Benami, Y Halfon, M Krupkin, ...
Nucleic acids research 45 (17), 10284-10292, 2017
Di‐N‐Methylation of Anti‐Gram‐Positive Aminoglycoside‐Derived Membrane Disruptors Improves Antimicrobial Potency and Broadens Spectrum to Gram …
RI Benhamou, P Shaul, IM Herzog, M Fridman
Angewandte Chemie 127 (46), 13821-13825, 2015
Synthesis and evaluation of hetero-and homodimers of ribosome-targeting antibiotics: antimicrobial activity, in vitro inhibition of translation, and drug resistance
Y Berkov-Zrihen, KD Green, KJ Labby, M Feldman, S Garneau-Tsodikova, ...
Journal of medicinal chemistry 56 (13), 5613-5625, 2013
Design of membrane targeting tobramycin-based cationic amphiphiles with reduced hemolytic activity
IM Herzog, M Feldman, A Eldar-Boock, R Satchi-Fainaro, M Fridman
MedChemComm 4 (1), 120-124, 2013
Antimycobacterial activity of DNA intercalator inhibitors of Mycobacterium tuberculosis primase DnaG
C Gajadeera, MJ Willby, KD Green, P Shaul, M Fridman, ...
The Journal of antibiotics 68 (3), 153-157, 2015
Phosphonium pillar [5] arenes as a new class of efficient biofilm inhibitors: importance of charge cooperativity and the pillar platform
R Joseph, D Kaizerman, IM Herzog, M Hadar, M Feldman, M Fridman, ...
Chemical Communications 52 (70), 10656-10659, 2016
Tobramycin and Nebramine as Pseudo‐oligosaccharide Scaffolds for the Development of Antimicrobial Cationic Amphiphiles
Y Berkov‐Zrihen, IM Herzog, RI Benhamou, M Feldman, KB Steinbuch, ...
Chemistry–A European Journal 21 (11), 4340-4349, 2015
The structure of anthracycline derivatives determines their subcellular localization and cytotoxic activity
P Shaul, M Frenkel, EB Goldstein, L Mittelman, A Grunwald, Y Ebenstein, ...
ACS medicinal chemistry letters 4 (3), 323-328, 2013
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