Inhibiting WEE1 selectively kills histone H3K36me3-deficient cancers by dNTP starvation SX Pfister, E Markkanen, Y Jiang, S Sarkar, M Woodcock, G Orlando, ... Cancer cell 28 (5), 557-568, 2015 | 309 | 2015 |
Association analyses identify 31 new risk loci for colorectal cancer susceptibility PJ Law, M Timofeeva, C Fernandez-Rozadilla, P Broderick, J Studd, ... Nature communications 10 (1), 2154, 2019 | 228 | 2019 |
Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor K Litchfield, M Levy, G Orlando, C Loveday, PJ Law, G Migliorini, ... Nature genetics 49 (7), 1133-1140, 2017 | 141 | 2017 |
Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma M Went, A Sud, A Försti, BM Halvarsson, N Weinhold, S Kimber, ... Nature communications 9 (1), 3707, 2018 | 125 | 2018 |
Promoter capture Hi-C-based identification of recurrent noncoding mutations in colorectal cancer G Orlando, PJ Law, AJ Cornish, SE Dobbins, D Chubb, P Broderick, ... Nature genetics 50 (10), 1375-1380, 2018 | 69 | 2018 |
Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease G Orlando, PJ Law, K Palin, S Tuupanen, A Gylfe, UA Hänninen, T Cajuso, ... Human molecular genetics 25 (11), 2349-2359, 2016 | 54 | 2016 |
Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility A Sud, H Thomsen, PJ Law, A Försti, MIS Filho, A Holroyd, P Broderick, ... Nature communications 8 (1), 1892, 2017 | 52 | 2017 |
Insight into genetic predisposition to chronic lymphocytic leukemia from integrative epigenomics HE Speedy, R Beekman, V Chapaprieta, G Orlando, PJ Law, ... Nature Communications 10 (1), 3615, 2019 | 45 | 2019 |
Genome-wide association analysis of chronic lymphocytic leukaemia, Hodgkin lymphoma and multiple myeloma identifies pleiotropic risk loci PJ Law, A Sud, JS Mitchell, M Henrion, G Orlando, O Lenive, P Broderick, ... Scientific reports 7 (1), 41071, 2017 | 45 | 2017 |
Multiple myeloma risk variant at 7p15.3 creates an IRF4-binding site and interferes with CDCA7L expression N Li, DC Johnson, N Weinhold, JB Studd, G Orlando, F Mirabella, ... Nature communications 7 (1), 13656, 2016 | 44 | 2016 |
ARF induction in response to DNA strand breaks is regulated by PARP1 G Orlando, SV Khoronenkova, II Dianova, JL Parsons, GL Dianov Nucleic acids research 42 (4), 2320-2329, 2014 | 40 | 2014 |
Genome‐wide association study and meta‐analysis in Northern European populations replicate multiple colorectal cancer risk loci T Tanskanen, L Van Den Berg, N Välimäki, M Aavikko, E Ness‐Jensen, ... International Journal of Cancer 142 (3), 540-546, 2018 | 32 | 2018 |
Genome-wide association study implicates immune dysfunction in the development of Hodgkin lymphoma A Sud, H Thomsen, G Orlando, A Foersti, PJ Law, P Broderick, R Cooke, ... Blood, The Journal of the American Society of Hematology 132 (19), 2040-2052, 2018 | 30 | 2018 |
Identification of recurrent noncoding mutations in B-cell lymphoma using capture Hi-C AJ Cornish, PH Hoang, SE Dobbins, PJ Law, D Chubb, G Orlando, ... Blood Advances 3 (1), 21-32, 2019 | 25 | 2019 |
Genetic predisposition to multiple myeloma at 5q15 is mediated by an ELL2 enhancer polymorphism N Li, DC Johnson, N Weinhold, S Kimber, SE Dobbins, JS Mitchell, ... Cell reports 20 (11), 2556-2564, 2017 | 25 | 2017 |
Capture Hi‐C Library Generation and Analysis to Detect Chromatin Interactions G Orlando, B Kinnersley, RS Houlston Current protocols in human genetics 98 (1), e63, 2018 | 22 | 2018 |
Genetic correlation between multiple myeloma and chronic lymphocytic leukaemia provides evidence for shared aetiology M Went, A Sud, H Speedy, NJ Sunter, A Försti, PJ Law, DC Johnson, ... Blood cancer journal 9 (1), 1, 2018 | 19 | 2018 |
Transcriptome-wide association study of multiple myeloma identifies candidate susceptibility genes M Went, B Kinnersley, A Sud, DC Johnson, N Weinhold, A Försti, ... Human genomics 13, 1-8, 2019 | 18 | 2019 |
Author Correction: Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma M Went, A Sud, A Försti, BM Halvarsson, N Weinhold, S Kimber, ... Nature Communications 10 (1), 213, 2019 | 2 | 2019 |
Chromothripsis orchestrates leukemic transformation in blast phase MPN through targetable amplification of DYRK1A CK Brierley, BH Yip, G Orlando, H Goyal, S Wen, J Wen, MF Levine, ... Blood 142, 993, 2023 | 1 | 2023 |