Nina Pipalia
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Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts
NH Pipalia, CC Cosner, A Huang, A Chatterjee, P Bourbon, N Farley, ...
Proceedings of the National Academy of Sciences 108 (14), 5620-5625, 2011
Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing
M Crespo, E Vilar, SY Tsai, K Chang, S Amin, T Srinivasan, T Zhang, ...
Nature medicine 23 (7), 878, 2017
Neuroprotection by cyclodextrin in cell and mouse models of Alzheimer disease
J Yao, D Ho, NY Calingasan, NH Pipalia, MT Lin, MF Beal
Journal of Experimental Medicine 209 (13), 2501-2513, 2012
STARD4 abundance regulates sterol transport and sensing
B Mesmin, NH Pipalia, FW Lund, TF Ramlall, A Sokolov, D Eliezer, ...
Molecular biology of the cell 22 (21), 4004-4015, 2011
Improvement in lipid and protein trafficking in Niemann‐Pick C1 cells by correction of a secondary enzyme defect
C Devlin, NH Pipalia, X Liao, EH Schuchman, FR Maxfield, I Tabas
Traffic 11 (5), 601-615, 2010
Automated microscopy screening for compounds that partially revert cholesterol accumulation in Niemann-Pick C cells
NH Pipalia, A Huang, H Ralph, M Rujoi, FR Maxfield
Journal of lipid research 47 (2), 284-301, 2006
A murine Niemann-Pick C1 I1061T knock-in model recapitulates the pathological features of the most prevalent human disease allele
M Praggastis, B Tortelli, J Zhang, H Fujiwara, R Sidhu, A Chacko, Z Chen, ...
Journal of Neuroscience 35 (21), 8091-8106, 2015
A novel mechanism for protein delivery: granzyme B undergoes electrostatic exchange from serglycin to target cells
SM Raja, SS Metkar, S Höning, B Wang, WA Russin, NH Pipalia, ...
Journal of Biological Chemistry 280 (21), 20752-20761, 2005
Sterol, protein and lipid trafficking in Chinese hamster ovary cells with Niemann‐Pick type C1 defect
NH Pipalia, M Hao, S Mukherjee, FR Maxfield
Traffic 8 (2), 130-141, 2007
A carbon nanotube optical reporter maps endolysosomal lipid flux
PV Jena, D Roxbury, TV Galassi, L Akkari, CP Horoszko, DB Iaea, ...
ACS nano 11 (11), 10689-10703, 2017
Histone deacetylase inhibitors correct the cholesterol storage defect in most Niemann-Pick C1 mutant cells
NH Pipalia, K Subramanian, S Mao, H Ralph, DM Hutt, SM Scott, ...
Journal of lipid research 58 (4), 695-708, 2017
Role of STARD4 and NPC1 in intracellular sterol transport
FR Maxfield, DB Iaea, NH Pipalia
Biochemistry and Cell Biology 94 (6), 499-506, 2016
Efficiency of immunotoxin cytotoxicity is modulated by the intracellular itinerary
LL Tortorella, NH Pipalia, S Mukherjee, I Pastan, D Fitzgerald, ...
PLoS One 7 (10), e47320, 2012
Cholesterol pathways affected by small molecules that decrease sterol levels in Niemann-Pick type C mutant cells
M Rujoi, NH Pipalia, FR Maxfield
PLoS One 5 (9), e12788, 2010
Important region in the β‐spectrin C‐terminus for spectrin tetramer formation
BH Luo, S Mehboob, MG Hurtuk, NH Pipalia, LWM Fung
European journal of haematology 68 (2), 73-79, 2002
2-Hydroxypropyl-β-cyclodextrin is the active component in a triple combination formulation for treatment of Niemann-Pick C1 disease
J Davidson, E Molitor, S Moores, SE Gale, K Subramanian, X Jiang, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2019
Cholesterol and matrisome pathways dysregulated in human APOE ε4 glia
TCW Julia, SA Liang, L Qian, NH Pipalia, MJ Chao, Y Shi, SE Bertelsen, ...
BioRxiv, 713362, 2019
The L49F mutation in alpha erythroid spectrin induces local disorder in the tetramer association region: fluorescence and molecular dynamics studies of free and bound alpha …
Y Song, NH Pipalia, LWM Fung
Protein Science 18 (9), 1916-1925, 2009
Cholesterol and Matrisome Pathways Dysregulated in Human APOE∊ 4 Glia
SA Liang, L Qian, NH Pipalia, MJ Chao, SE Bertelsen, M Kapoor, ...
Available at SSRN 3435267, 2019
Parallel analysis of v-Src mutant protein function using reverse transfection cell arrays
W Walczak, NH Pipalia, M Soni, AF Faruqi, H Ralph, FR Maxfield, ...
Combinatorial chemistry & high throughput screening 9 (9), 711-718, 2006
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