| Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing M Crespo, E Vilar, SY Tsai, K Chang, S Amin, T Srinivasan, T Zhang, ... Nature medicine 23 (7), 878-884, 2017 | 339 | 2017 |
| Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts NH Pipalia, CC Cosner, A Huang, A Chatterjee, P Bourbon, N Farley, ... Proceedings of the National Academy of Sciences 108 (14), 5620-5625, 2011 | 250 | 2011 |
| Neuroprotection by cyclodextrin in cell and mouse models of Alzheimer disease J Yao, D Ho, NY Calingasan, NH Pipalia, MT Lin, MF Beal Journal of Experimental Medicine 209 (13), 2501-2513, 2012 | 166 | 2012 |
| Cholesterol and matrisome pathways dysregulated in astrocytes and microglia TCW Julia, L Qian, NH Pipalia, MJ Chao, SA Liang, Y Shi, BR Jain, ... Cell 185 (13), 2213-2233. e25, 2022 | 146 | 2022 |
| STARD4 abundance regulates sterol transport and sensing B Mesmin, NH Pipalia, FW Lund, TF Ramlall, A Sokolov, D Eliezer, ... Molecular biology of the cell 22 (21), 4004-4015, 2011 | 128 | 2011 |
| A murine Niemann-Pick C1 I1061T knock-in model recapitulates the pathological features of the most prevalent human disease allele M Praggastis, B Tortelli, J Zhang, H Fujiwara, R Sidhu, A Chacko, Z Chen, ... Journal of Neuroscience 35 (21), 8091-8106, 2015 | 120 | 2015 |
| A carbon nanotube optical reporter maps endolysosomal lipid flux PV Jena, D Roxbury, TV Galassi, L Akkari, CP Horoszko, DB Iaea, ... ACS nano 11 (11), 10689-10703, 2017 | 102 | 2017 |
| Improvement in lipid and protein trafficking in Niemann‐Pick C1 cells by correction of a secondary enzyme defect C Devlin, NH Pipalia, X Liao, EH Schuchman, FR Maxfield, I Tabas Traffic 11 (5), 601-615, 2010 | 95 | 2010 |
| Automated microscopy screening for compounds that partially revert cholesterol accumulation in Niemann-Pick C cells NH Pipalia, A Huang, H Ralph, M Rujoi, FR Maxfield Journal of lipid research 47 (2), 284-301, 2006 | 94 | 2006 |
| A novel mechanism for protein delivery: granzyme B undergoes electrostatic exchange from serglycin to target cells SM Raja, SS Metkar, S Honing, B Wang, WA Russin, NH Pipalia, ... Journal of Biological Chemistry 280 (21), 20752-20761, 2005 | 78 | 2005 |
| Sterol, protein and lipid trafficking in Chinese hamster ovary cells with Niemann‐Pick type C1 defect NH Pipalia, M Hao, S Mukherjee, FR Maxfield Traffic 8 (2), 130-141, 2007 | 70 | 2007 |
| Histone deacetylase inhibitors correct the cholesterol storage defect in most Niemann-Pick C1 mutant cells NH Pipalia, K Subramanian, S Mao, H Ralph, DM Hutt, SM Scott, ... Journal of lipid research 58 (4), 695-708, 2017 | 68 | 2017 |
| Cholesterol and matrisome pathways dysregulated in human APOE ε4 glia J Tcw, SA Liang, L Qian, NH Pipalia, MJ Chao, Y Shi, SE Bertelsen, ... BioRxiv, 713362, 2019 | 43 | 2019 |
| Role of STARD4 and NPC1 in intracellular sterol transport FR Maxfield, DB Iaea, NH Pipalia Biochemistry and Cell Biology 94 (6), 499-506, 2016 | 26 | 2016 |
| 2-Hydroxypropyl-β-cyclodextrin is the active component in a triple combination formulation for treatment of Niemann-Pick C1 disease J Davidson, E Molitor, S Moores, SE Gale, K Subramanian, X Jiang, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2019 | 25 | 2019 |
| Efficiency of immunotoxin cytotoxicity is modulated by the intracellular itinerary LL Tortorella, NH Pipalia, S Mukherjee, I Pastan, D Fitzgerald, ... Public Library of Science 7 (10), e47320, 2012 | 19 | 2012 |
| Cholesterol pathways affected by small molecules that decrease sterol levels in Niemann-Pick type C mutant cells M Rujoi, NH Pipalia, FR Maxfield PLoS One 5 (9), e12788, 2010 | 15 | 2010 |
| Important region in the β‐spectrin C‐terminus for spectrin tetramer formation BH Luo, S Mehboob, MG Hurtuk, NH Pipalia, LWM Fung European journal of haematology 68 (2), 73-79, 2002 | 15 | 2002 |
| HSP90 inhibitors reduce cholesterol storage in Niemann-Pick type C1 mutant fibroblasts NH Pipalia, SZ Saad, K Subramanian, A Cross, A Al-Motawa, K Garg, ... Journal of Lipid Research 62, 2021 | 9 | 2021 |
| The L49F mutation in alpha erythroid spectrin induces local disorder in the tetramer association region: fluorescence and molecular dynamics studies of free and bound alpha … Y Song, NH Pipalia, LWM Fung Protein Science 18 (9), 1916-1925, 2009 | 7 | 2009 |
Fred MaxfieldWeill Cornell Medical CollegeVerified email at med.cornell.edu
