Age-associated microbial dysbiosis promotes intestinal permeability, systemic inflammation, and macrophage dysfunction N Thevaranjan, A Puchta, C Schulz, A Naidoo, JC Szamosi, ... Cell host & microbe 21 (4), 455-466. e4, 2017 | 1128 | 2017 |
Clostridium difficile toxin–induced inflammation and intestinal injury are mediated by the inflammasome J Ng, SA Hirota, O Gross, Y Li, A Ulke–Lemee, MS Potentier, LP Schenck, ... Gastroenterology 139 (2), 542-552. e3, 2010 | 267 | 2010 |
Composition and immunological significance of the upper respiratory tract microbiota LP Schenck, MG Surette, DME Bowdish FEBS letters 590 (21), 3705-3720, 2016 | 126 | 2016 |
Amphiregulin-producing γδ T cells are vital for safeguarding oral barrier immune homeostasis S Krishnan, IE Prise, K Wemyss, LP Schenck, HM Bridgeman, FA McClure, ... Proceedings of the National Academy of Sciences 115 (42), 10738-10743, 2018 | 96 | 2018 |
Giardia duodenalis infection reduces granulocyte infiltration in an in vivo model of bacterial toxin-induced colitis and attenuates inflammation in human intestinal tissue JA Cotton, JP Motta, LP Schenck, SA Hirota, PL Beck, AG Buret PloS one 9 (10), e109087, 2014 | 87 | 2014 |
Microbial dysbiosis and mortality during mechanical ventilation: a prospective observational study D Lamarche, J Johnstone, N Zytaruk, F Clarke, L Hand, D Loukov, ... Respiratory Research 19, 1-12, 2018 | 75 | 2018 |
The P2Y6 Receptor Mediates Clostridium difficile Toxin-Induced CXCL8/IL-8 Production and Intestinal Epithelial Barrier Dysfunction A Hansen, L Alston, SE Tulk, LP Schenck, ME Grassie, BF Alhassan, ... PloS one 8 (11), e81491, 2013 | 59 | 2013 |
Intrarectal instillation of Clostridium difficile toxin A triggers colonic inflammation and tissue damage: development of a novel and efficient mouse model of Clostridium … SA Hirota, V Iablokov, SE Tulk, LP Schenck, H Becker, J Nguyen, ... Infection and immunity 80 (12), 4474-4484, 2012 | 56 | 2012 |
Unique microbial-derived volatile organic compounds in portal venous circulation in murine non-alcoholic fatty liver disease DT Reid, B McDonald, T Khalid, T Vo, LP Schenck, MG Surette, PL Beck, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1862 (7 …, 2016 | 32 | 2016 |
Gastrointestinal dysbiosis and the use of fecal microbial transplantation in Clostridium difficile infection LP Schenck, PL Beck, JA MacDonald World journal of gastrointestinal pathophysiology 6 (4), 169, 2015 | 26 | 2015 |
Streptococcus pneumoniae colonization is required to alter the nasal microbiota in cigarette smoke-exposed mice P Shen, FJ Whelan, LP Schenck, JJC McGrath, G Vanderstocken, ... Infection and immunity 85 (10), 10.1128/iai. 00434-17, 2017 | 15 | 2017 |
Attenuation of Clostridium difficile toxin‐induced damage to epithelial barrier by ecto‐5′‐nucleotidase (CD73) and adenosine receptor signaling L Patrick Schenck, SA Hirota, CL Hirota, P Boasquevisque, SE Tulk, Y Li, ... Neurogastroenterology & Motility 25 (6), e441-e453, 2013 | 13 | 2013 |
Cigarette smoke exposure attenuates the induction of antigen-specific IgA in the murine upper respiratory tract JJC McGrath, D Thayaparan, SP Cass, JP Mapletoft, PYF Zeng, ... Mucosal Immunology 14 (5), 1067-1076, 2021 | 12 | 2021 |
The Src kinase Fyn is protective in acute chemical-induced colitis and promotes recovery from disease F Lopes, A Wang, D Smyth, JL Reyes, A Doering, LP Schenck, P Beck, ... Journal of Leucocyte Biology 97 (6), 1089-1099, 2015 | 10 | 2015 |
Nasal tissue extraction is essential for characterization of the murine upper respiratory tract microbiota LP Schenck, JJC McGrath, D Lamarche, MR Stämpfli, DME Bowdish, ... Msphere 5 (6), 10.1128/msphere. 00562-20, 2020 | 8 | 2020 |
Exaggerated IL‐15 and Altered Expression of foxp3+ Cell‐Derived Cytokines Contribute to Enhanced Colitis in Nlrp3−/− Mice SA Hirota, A Ueno, SE Tulk, HM Becker, LP Schenck, MS Potentier, Y Li, ... Mediators of inflammation 2016 (1), 5637685, 2016 | 4 | 2016 |
The impact of respiratory infections and probiotic use on the nasal microbiota of frail residents in long-term care homes DME Bowdish, L Rossi, M Loeb, J Johnstone, LP Schenck, M Fontes, ... ERJ Open Research 9 (5), 2023 | 1 | 2023 |
1000 Elucidating Intestinal Microbiota Components That Play a Protective or Deleterious Role During Clostridium difficile Infections LP Schenck, SA Hirota, GD Armstrong, JA MacDonald, PL Beck Gastroenterology 5 (144), S-185, 2013 | 1 | 2013 |
CD73-Mediated liberation of adenosine protects intestinal epithelial cells from C. difficile toxin-induced damage LP Schenck, SA Hirota, MS Potentier, Y Li, GD Armstrong, PL Beck, ... Gastroenterology 5 (140), S-498, 2011 | 1 | 2011 |
Inhibition of Nasal and Systemic IgA Responses by Cigarette Smoke Exposure in Mice J McGrath, D Thayaparan, S Cass, B Ly, R Heo, S Afkhami, J Koenig, ... C63. MECHANISTIC STUDIES IN COPD, A5379-A5379, 2019 | | 2019 |