Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2 T Klemm, G Ebert, DJ Calleja, CC Allison, LW Richardson, JP Bernardini, ... The EMBO journal 39 (18), e106275, 2020 | 442 | 2020 |
Towards rationalization of crystallization screening for small-to medium-sized academic laboratories: the PACT/JCSG+ strategy J Newman, D Egan, TS Walter, R Meged, I Berry, M Ben Jelloul, ... Acta Crystallographica Section D: Biological Crystallography 61 (10), 1426-1431, 2005 | 321 | 2005 |
Structural analysis of a set of proteins resulting from a bacterial genomics project J Badger, JM Sauder, JM Adams, S Antonysamy, K Bain, MG Bergseid, ... Proteins: Structure, Function, and Bioinformatics 60 (4), 787-796, 2005 | 294 | 2005 |
Haloalkane Dehalogenases: Structure of a Rhodococcus Enzyme, J Newman, TS Peat, R Richard, L Kan, PE Swanson, JA Affholter, ... Biochemistry 38 (49), 16105-16114, 1999 | 272 | 1999 |
Crystal Structure of the Haloalkane Dehalogenase from Sphingomonas paucimobilis UT26, J Marek, J Vévodová, IK Smatanová, Y Nagata, LA Svensson, J Newman, ... Biochemistry 39 (46), 14082-14086, 2000 | 210 | 2000 |
Identification and characterization of two families of F420H2‐dependent reductases from Mycobacteria that catalyse aflatoxin degradation MC Taylor, CJ Jackson, DB Tattersall, N French, TS Peat, J Newman, ... Molecular microbiology 78 (3), 561-575, 2010 | 193 | 2010 |
Novel buffer systems for macromolecular crystallization J Newman Acta Crystallographica Section D: Biological Crystallography 60 (3), 610-612, 2004 | 166 | 2004 |
The X-ray structure of Synechococcus ribulose-bisphosphate carboxylase/oxygenase-activated quaternary complex at 2.2-A resolution. J Newman, S Gutteridge Journal of Biological Chemistry 268 (34), 25876-25886, 1993 | 150 | 1993 |
Structure of translation initiation factor 5A from Pyrobaculum aerophilum at 1.75 Å resolution TS Peat, J Newman, GS Waldo, J Berendzen, TC Terwilliger Structure 6 (9), 1207-1214, 1998 | 145 | 1998 |
HBO1 is required for the maintenance of leukaemia stem cells L MacPherson, J Anokye, MM Yeung, EYN Lam, YC Chan, CF Weng, ... Nature 577 (7789), 266-270, 2020 | 143 | 2020 |
Structural and functional basis of resistance to neuraminidase inhibitors of influenza B viruses AJ Oakley, S Barrett, TS Peat, J Newman, VA Streltsov, L Waddington, ... American Chemical Society, 2010 | 117 | 2010 |
Class‐directed structure determination: Foundation for a protein structure initiative TC Terwilliger, G Waldo, TS Peat, JM Newman, KC And, J Berendzen Protein Science 7 (9), 1851-1856, 1998 | 115 | 1998 |
Structural studies of Salmonella typhimurium ArnB (PmrH) aminotransferase: a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme BW Noland, JM Newman, J Hendle, J Badger, JA Christopher, J Tresser, ... Structure 10 (11), 1569-1580, 2002 | 113 | 2002 |
Rational engineering of a mesohalophilic carbonic anhydrase to an extreme halotolerant biocatalyst AC Warden, M Williams, TS Peat, SA Seabrook, J Newman, G Dojchinov, ... Nature Communications 6 (1), 10278, 2015 | 99 | 2015 |
Crystallization screening: the influence of history on current practice JR Luft, J Newman, EH Snell Acta Crystallographica Section F: Structural Biology Communications 70 (7 …, 2014 | 97 | 2014 |
Tray for macromolecule crystallization and method of using the same J Newman US Patent 6,656,267, 2003 | 96 | 2003 |
Crystal structure of an indole-3-acetic acid amido synthetase from grapevine involved in auxin homeostasis TS Peat, C Böttcher, J Newman, D Lucent, N Cowieson, C Davies The Plant Cell 24 (11), 4525-4538, 2012 | 92 | 2012 |
Classification of crystallization outcomes using deep convolutional neural networks AE Bruno, P Charbonneau, J Newman, EH Snell, DR So, V Vanhoucke, ... PLOS one 13 (6), e0198883, 2018 | 86 | 2018 |
Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification? J Wielens, SJ Headey, DI Rhodes, RJ Mulder, O Dolezal, JJ Deadman, ... Journal of Biomolecular Screening 18 (2), 147-159, 2013 | 85 | 2013 |
High-throughput thermal scanning for protein stability: making a good technique more robust SA Seabrook, J Newman ACS Combinatorial science 15 (8), 387-392, 2013 | 81 | 2013 |