Kim Brøsen

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Per DamkierVerified email at health.sdu.dk
Tore B. StageProfessor, Translational Pharmacology, University of Southern DenmarkVerified email at health.sdu.dk
Troels K BergmannAssociate professor, University of Southern Denmark, Odense, DenmarkVerified email at rsyd.dk
Lars Arendt-NielsenDirector, professor, dr med sci, ph dVerified email at hst.aau.dk
Jesper HallasUniversity of Southern DenmarkVerified email at health.sdu.dk
Henrik E. PoulsenProfessor Klinisk FarmakologiVerified email at rh.dk
Steffen LoftUniversity of Copenhagen, Department of Public HealthVerified email at sund.ku.dk
Henrik GreenLinköping University Verified email at liu.se
Niels JessenProfessor of Clinical Pharmacology, Aarhus UniversitetVerified email at clin.au.dk
Troels Staehelin JensenProfessor of Neurology, Aarhus UniversityVerified email at clin.au.dk
Werner VachSenior Researcher in Applied Methodology, Basel Academy for Quality and Research in MedicineVerified email at crossklinik.ch
Mirza MRNordic Society of Gynaecological OncologyVerified email at regionh.dk
Søren Mikkelsen, Professor, MD PhDPrehospital Research Unit, the Region of Southern Denmark, Odense University Hospital, DenmarkVerified email at rsyd.dk
Jorgen FrokiaerProfessor i medicin, Aarhus UniversitetVerified email at ki.au.dk
Mogens HorderUniversity of Southern DenamrkVerified email at health.sdu.dk
Lars Christian GormsenLektor, overlæge, Aarhus UniversitetshospitalVerified email at rm.dk
Peter BjerringProfessor, Department of Dermatology, Aalborg University HospitalVerified email at peterbjerring.dk
Kim BrixenMedical Director, Odense University HospitalVerified email at rsyd.dk
Ivar S KristiansenProfessor of community medicine University of OsloVerified email at medisin.uio.no
Anton PottegårdProfessor, University of Southern DenmarkVerified email at health.sdu.dk

Kim Brøsen

Professor in Clinical Pharmacology, University of Southern Denmark

Verified email at health.sdu.dk - Homepage

Pharmacogenetics drug metabolism dry-drug interactions pharmacogenetics


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The selective serotonin reuptake inhibitor paroxetine is effective in the treatment of diabetic neuropathy symptoms SH Sindrup, LF Gram, K Brøsen, O Eshøj, EF Mogensen Pain 42 (2), 135-144, 1990	634	1990
CYP2D6 and CYP2C19 genotype‐based dose recommendations for antidepressants: a first step towards subpopulation‐specific dosages J Kirchheiner, K Brøsen, ML Dahl, LF Gram, S Kasper, I Roots, F Sjöqvist, ... Acta Psychiatrica Scandinavica 104 (3), 173-192, 2001	568	2001
Paroxetine: a selective serotonin reuptake inhibitor showing better tolerance, but weaker antidepressant effect than clomipramine in a controlled multicenter study Danish University Antidepressant Group Journal of Affective Disorders 18 (4), 289-299, 1990	563	1990
The hypoalgesic effect of tramadol in relation to CYP2D6 L Poulsen, L Arendt‐Nielsen, K Brøsen, SH Sindrup Clinical Pharmacology & Therapeutics 60 (6), 636-644, 1996	481	1996
Tramadol relieves pain and allodynia in polyneuropathy: a randomised, double-blind, controlled trial SH Sindrup, G Andersen, C Madsen, T Smith, K Brøsen, TS Jensen Pain 83 (1), 85-90, 1999	477	1999
Drug related hospital admissions: the role of definitions and intensity of data collection, and the possibility of prevention J Hallas, B Harvald, LF Gram, E Grodum, K Brøsen, T Haghfelt, N Damsbo Journal of internal medicine 228 (2), 83-90, 1990	468	1990
Fluvoxamine is a potent inhibitor of cytochrome P4501A2 K Brøsen, E Skjelbo, BB Rasmussen, HE Poulsen, S Loft Biochemical pharmacology 45 (6), 1211-1214, 1993	444	1993
Dose-dependent inhibition of CYP1A2, CYP2C19 and CYP2D6 by citalopram, fluoxetine, fluvoxamine and paroxetine U Jeppesen, LF Gram, K Vistisen, S Loft, HE Poulsen, K Brøsen European journal of clinical pharmacology 51, 73-78, 1996	420	1996
The selective serotonin reuptake inhibitor citalopram relieves the symptoms of diabetic neuropathy SH Sindrup, U Bjerre, A Dejgaard, K Brøsen, T Aaes‐Jørgensen, LF Gram Clinical Pharmacology & Therapeutics 52 (5), 547-552, 1992	389	1992
Clinical significance of the sparteine/debrisoquine oxidation polymorphism K Brøsen, LF Gram European Journal of Clinical Pharmacology 36, 537-547, 1989	374	1989
Drug related admissions to medical wards: a population based survey. J Hallas, LF Gram, E Grodum, N Damsbo, K Brosen, T Haghfelt, B Harvald, ... British journal of clinical pharmacology 33 (1), 61-68, 1992	316	1992
Codeine and morphine in extensive and poor metabolizers of sparteine: pharmacokinetics, analgesic effect and side effects L Poulsen, K Brøsen, L Arendt-Nielsen, LF Gram, K Elbaek, SH Sindrup European journal of clinical pharmacology 51, 289-295, 1996	309	1996
The pharmacogenetics of metformin and its impact on plasma metformin steady-state levels and glycosylated hemoglobin A1c MMH Christensen, C Brasch-Andersen, H Green, F Nielsen, P Damkier, ... Pharmacogenetics and genomics 21 (12), 837-850, 2011	298	2011
The interindividual differences in the 3-demthylation of caffeine alias CYP1A2 is determined by both genetic and environmental factors BB Rasmussen, TH Brix, KO Kyvik, K Brøsen Pharmacogenetics and Genomics 12 (6), 473-478, 2002	281	2002
Pharmacokinetics of citalopram in relation to the sparteine and the mephenytoin oxidation polymorphisms SH Sindrup, K Brøsen, MGJ Hansen, T Aaes-Jørgensen, KF Overø, ... Therapeutic drug monitoring 15 (1), 11-17, 1993	273	1993
The relationship between paroxetine and the sparteine oxidation polymorphism SH Sindrup, K Brøsen, LF Gram, J Hallas, E Skjelbo, A Allen, GD Allen, ... Clinical Pharmacology & Therapeutics 51 (3), 278-287, 1992	259	1992
The pharmacogenetics of codeine hypoalgesia SH Sindrup, K Brøsen Pharmacogenetics and Genomics 5 (6), 335-346, 1995	251	1995
Recent developments in hepatic drug oxidation implications for clinical pharmacokinetics K Brosen Clinical pharmacokinetics 18, 220-239, 1990	250	1990
Inhibition by paroxetine of desipramine metabolism in extensive but not in poor metabolizers of sparteine K Brøsen, JG Hansen, KK Nielsen, SH Sindrup, LF Gram European journal of clinical pharmacology 44, 349-355, 1993	236	1993
Inhibitors of imipramine metabolism by human liver microsomes. E Skjelbo, K Brosen British journal of clinical pharmacology 34 (3), 256-261, 1992	217	1992

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