Anthony William Paul Fitzpatrick
Anthony William Paul Fitzpatrick
Assistant Professor, Department of Biochemistry & Molecular Biophysics, Columbia University, NYC
Verified email at columbia.edu - Homepage
Title
Cited by
Cited by
Year
Cryo-EM structures of tau filaments from Alzheimer’s disease
AWP Fitzpatrick, B Falcon, S He, AG Murzin, G Murshudov, HJ Garringer, ...
Nature 547 (7662), 185-190, 2017
10212017
Role of intermolecular forces in defining material properties of protein nanofibrils
TP Knowles, AW Fitzpatrick, S Meehan, HR Mott, M Vendruscolo, ...
science 318 (5858), 1900-1903, 2007
7222007
Atomic structure and hierarchical assembly of a cross-β amyloid fibril
AWP Fitzpatrick, GT Debelouchina, MJ Bayro, DK Clare, MA Caporini, ...
Proceedings of the National Academy of Sciences 110 (14), 5468-5473, 2013
4942013
Metastability of native proteins and the phenomenon of amyloid formation
AJ Baldwin, TPJ Knowles, GG Tartaglia, AW Fitzpatrick, GL Devlin, ...
Journal of the American Chemical Society 133 (36), 14160-14163, 2011
4012011
Posttranslational modifications mediate the structural diversity of tauopathy strains
T Arakhamia, CE Lee, Y Carlomagno, DM Duong, SR Kundinger, K Wang, ...
Cell 180 (4), 633-644. e12, 2020
1382020
Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump
AWP Fitzpatrick, S Llabrés, A Neuberger, JN Blaza, XC Bai, U Okada, ...
Nature Microbiology 2, 17070, 2017
1022017
Inversion of the balance between hydrophobic and hydrogen bonding interactions in protein folding and aggregation
AW Fitzpatrick, TPJ Knowles, CA Waudby, M Vendruscolo, CM Dobson
PLoS computational biology 7 (10), e1002169, 2011
852011
Exceptional rigidity and biomechanics of amyloid revealed by 4D electron microscopy
AWP Fitzpatrick, ST Park, AH Zewail
Proceedings of the National Academy of Sciences 110 (27), 10976-10981, 2013
812013
In-cell NMR characterization of the secondary structure populations of a disordered conformation of α-synuclein within E. coli cells
CA Waudby, C Camilloni, AWP Fitzpatrick, LD Cabrita, CM Dobson, ...
PloS one 8 (8), e72286, 2013
752013
Higher order amyloid fibril structure by MAS NMR and DNP spectroscopy
GT Debelouchina, MJ Bayro, AW Fitzpatrick, V Ladizhansky, MT Colvin, ...
Journal of the American Chemical Society 135 (51), 19237-19247, 2013
732013
Four-dimensional electron microscopy: Ultrafast imaging, diffraction and spectroscopy in materials science and biology
GM Vanacore, AWP Fitzpatrick, AH Zewail
Nano Today 11 (2), 228-249, 2016
592016
Twisting transition between crystalline and fibrillar phases of aggregated peptides
TPJ Knowles, A De Simone, AW Fitzpatrick, A Baldwin, S Meehan, ...
Physical review letters 109 (15), 158101, 2012
522012
Cryo-EM of amyloid fibrils and cellular aggregates
AWP Fitzpatrick, HR Saibil
Current opinion in structural biology 58, 34-42, 2019
452019
Nanomechanics and intermolecular forces of amyloid revealed by four-dimensional electron microscopy
AWP Fitzpatrick, GM Vanacore, AH Zewail
Proceedings of the National Academy of Sciences 112 (11), 3380-3385, 2015
392015
Bottom-up structural proteomics: cryoEM of protein complexes enriched from the cellular milieu
CM Ho, X Li, M Lai, TC Terwilliger, JR Beck, J Wohlschlegel, DE Goldberg, ...
Nature methods 17 (1), 79-85, 2020
352020
4D cryo-electron microscopy of proteins
AWP Fitzpatrick, UJ Lorenz, GM Vanacore, AH Zewail
Journal of the American Chemical Society 135 (51), 19123-19126, 2013
342013
Accurate determination of interstrand distances and alignment in amyloid fibrils by magic angle spinning NMR
MA Caporini, VS Bajaj, M Veshtort, A Fitzpatrick, CE MacPhee, ...
The Journal of Physical Chemistry B 114 (42), 13555-13561, 2010
322010
Characterizing the first steps of amyloid formation for the ccβ peptide
B Strodel, AW Fitzpatrick, M Vendruscolo, CM Dobson, DJ Wales
The Journal of Physical Chemistry B 112 (32), 9998-10004, 2008
152008
The AD tau core spontaneously self-assembles and recruits full-length tau to filaments
Y Carlomagno, S Manne, M DeTure, M Prudencio, YJ Zhang, ...
Cell reports 34 (11), 108843, 2021
22021
Role of molecular polymorphism in defining tau filament structures in neurodegenerative diseases
X Xiang, T Arakhamia, Y Carlomagno, S Dhingra, M Thierry, M DeTure, ...
bioRxiv, 2021
2021
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