Discovery of CGS 27023A, a non-peptidic, potent, and orally active stromelysin inhibitor that blocks cartilage degradation in rabbits LJ MacPherson, EK Bayburt, MP Capparelli, BJ Carroll, R Goldstein, ... Journal of medicinal chemistry 40 (16), 2525-2532, 1997 | 405 | 1997 |
The Post-Polyketide Synthase Modification Steps in the Biosynthesis of the Antitumor Agent Ansamitocin by Actinosynnema p retiosum P Spiteller, L Bai, G Shang, BJ Carroll, TW Yu, HG Floss Journal of the American Chemical Society 125 (47), 14236-14237, 2003 | 97 | 2003 |
Intramolecular proton transfer in the cyclization of geranylgeranyl diphosphate to the taxadiene precursor of taxol catalyzed by recombinant taxadiene synthase DC Williams, BJ Carroll, Q Jin, CD Rithner, SR Lenger, HG Floss, ... Chemistry & biology 7 (12), 969-977, 2000 | 92 | 2000 |
Identification of a set of genes involved in the formation of the substrate for the incorporation of the unusual “glycolate” chain extension unit in ansamitocin biosynthesis BJ Carroll, SJ Moss, L Bai, Y Kato, S Toelzer, TW Yu, HG Floss Journal of the American Chemical Society 124 (16), 4176-4177, 2002 | 91 | 2002 |
On the biosynthetic origin of methoxymalonyl-acyl carrier protein, the substrate for incorporation of “glycolate” units into ansamitocin and soraphen A SC Wenzel, RM Williamson, C Grünanger, J Xu, K Gerth, RA Martinez, ... Journal of the American Chemical Society 128 (44), 14325-14336, 2006 | 86 | 2006 |
Identification of asm19 as an acyltransferase attaching the biologically essential ester side chain of ansamitocins using N-desmethyl-4, 5-desepoxymaytansinol, not maytansinol … SJ Moss, L Bai, S Toelzer, BJ Carroll, T Mahmud, TW Yu, HG Floss Journal of the American Chemical Society 124 (23), 6544-6545, 2002 | 55 | 2002 |
N‐methylation of the amide bond by methyltransferase asm10 in ansamitocin biosynthesis Y Wu, Q Kang, G Shang, P Spiteller, B Carroll, TW Yu, W Su, L Bai, ... ChemBioChem 12 (11), 1759-1766, 2011 | 22 | 2011 |