Jeff Saucerman
Jeff Saucerman
Professor of Biomedical Engineering and Cardiovascular Medicine, University of Virginia
Verified email at - Homepage
Cited by
Cited by
Modeling β-adrenergic control of cardiac myocyte contractility in silico
JJ Saucerman, LL Brunton, AP Michailova, AD McCulloch
Journal of Biological Chemistry 278 (48), 47997-48003, 2003
Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy
RC Laker, JC Drake, RJ Wilson, VA Lira, BM Lewellen, KA Ryall, ...
Nature communications 8 (1), 1-13, 2017
Systems analysis of PKA-mediated phosphorylation gradients in live cardiac myocytes
JJ Saucerman, J Zhang, JC Martin, LX Peng, AE Stenbit, RY Tsien, ...
Proceedings of the National Academy of Sciences 103 (34), 12923-12928, 2006
A novel MitoTimer reporter gene for mitochondrial content, structure, stress, and damage in vivo
RC Laker, P Xu, KA Ryall, A Sujkowski, BM Kenwood, KH Chain, ...
Journal of Biological Chemistry 289 (17), 12005-12015, 2014
Calmodulin mediates differential sensitivity of CaMKII and calcineurin to local Ca2+ in cardiac myocytes
JJ Saucerman, DM Bers
Biophysical journal 95 (10), 4597-4612, 2008
Local plantar pressure relief in therapeutic footwear: design guidelines from finite element models
A Erdemir, JJ Saucerman, D Lemmon, B Loppnow, B Turso, JS Ulbrecht, ...
Journal of biomechanics 38 (9), 1798-1806, 2005
Proarrhythmic consequences of a KCNQ1 AKAP-binding domain mutation: computational models of whole cells and heterogeneous tissue
JJ Saucerman, SN Healy, ME Belik, JL Puglisi, AD McCulloch
Circulation research 95 (12), 1216-1224, 2004
Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane
BM Kenwood, JL Weaver, A Bajwa, IK Poon, FL Byrne, BA Murrow, ...
Molecular metabolism 3 (2), 114-123, 2014
Synergy between CaMKII substrates and β-adrenergic signaling in regulation of cardiac myocyte Ca2+ handling
AR Soltis, JJ Saucerman
Biophysical journal 99 (7), 2038-2047, 2010
Regulation of nuclear PKA revealed by spatiotemporal manipulation of cyclic AMP
V Sample, LM DiPilato, JH Yang, Q Ni, JJ Saucerman, J Zhang
Nature chemical biology 8 (4), 375-382, 2012
Endotoxin depresses heart rate variability in mice: cytokine and steroid effects
KD Fairchild, JJ Saucerman, LL Raynor, JA Sivak, Y Xiao, DE Lake, ...
American Journal of Physiology-Regulatory, Integrative and Comparative …, 2009
Mapping macrophage polarization over the myocardial infarction time continuum
AJ Mouton, KY DeLeon-Pennell, OJR Gonzalez, ER Flynn, TC Freeman, ...
Basic research in cardiology 113 (4), 1-18, 2018
Mechanistic systems models of cell signaling networks: a case study of myocyte adrenergic regulation
JJ Saucerman, AD McCulloch
Progress in biophysics and molecular biology 85 (2-3), 261-278, 2004
Cardiac β‐Adrenergic Signaling: From Subcellular Microdomains to Heart Failure
JJ Saucerman, AD McCULLOCH
Annals of the New York Academy of Sciences 1080 (1), 348-361, 2006
Calmodulin binding proteins provide domains of local Ca2+ signaling in cardiac myocytes
JJ Saucerman, DM Bers
Journal of molecular and cellular cardiology 52 (2), 312-316, 2012
Network reconstruction and systems analysis of cardiac myocyte hypertrophy signaling
KA Ryall, DO Holland, KA Delaney, MJ Kraeutler, AJ Parker, ...
Journal of Biological Chemistry 287 (50), 42259-42268, 2012
Computational models reduce complexity and accelerate insight into cardiac signaling networks
JH Yang, JJ Saucerman
Circulation research 108 (1), 85-97, 2011
Differential integration of Ca2+-calmodulin signal in intact ventricular myocytes at low and high affinity Ca2+-calmodulin targets
Q Song, JJ Saucerman, J Bossuyt, DM Bers
Journal of Biological Chemistry 283 (46), 31531-31540, 2008
Modeling cardiac β-adrenergic signaling with normalized-Hill differential equations: comparison with a biochemical model
MJ Kraeutler, AR Soltis, JJ Saucerman
BMC systems biology 4 (1), 1-12, 2010
Mechanisms of cyclic AMP compartmentation revealed by computational models
JJ Saucerman, EC Greenwald, R Polanowska-Grabowska
The Journal of general physiology 143 (1), 39-48, 2014
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