עקוב אחר
Akshata Udyavar
Akshata Udyavar
Arcus Biosciences Inc
כתובת אימייל מאומתת בדומיין arcusbio.com
כותרת
צוטט על ידי
צוטט על ידי
שנה
Integrated digital pathology and transcriptome analysis identifies molecular mediators of T-cell exclusion in ovarian cancer
M Desbois, AR Udyavar, L Ryner, C Kozlowski, Y Guan, M Dürrbaum, ...
Nature communications 11 (1), 5583, 2020
1192020
Co-expression network analysis identifies Spleen Tyrosine Kinase (SYK) as a candidate oncogenic driver in a subset of small-cell lung cancer
AR Udyavar, MD Hoeksema, JE Clark, Y Zou, Z Tang, Z Li, M Li, H Chen, ...
BMC systems biology 7, 1-16, 2013
852013
Novel hybrid phenotype revealed in small cell lung cancer by a transcription factor network model that can explain tumor heterogeneity
AR Udyavar, DJ Wooten, M Hoeksema, M Bansal, A Califano, L Estrada, ...
Cancer Research 77 (5), 1063-1074, 2017
742017
DNA copy number aberrations in small-cell lung cancer reveal activation of the focal adhesion pathway
S Ocak, H Yamashita, AR Udyavar, AN Miller, AL Gonzalez, Y Zou, ...
Oncogene 29 (48), 6331-6342, 2010
522010
Subtle affinity-enhancing mutations in a myelin oligodendrocyte glycoprotein-specific TCR alter specificity and generate new self-reactivity
A Udyavar, R Alli, P Nguyen, L Baker, TL Geiger
The Journal of Immunology 182 (7), 4439-4447, 2009
502009
Rebalancing immune specificity and function in cancer by T-cell receptor gene therapy
A Udyavar, TL Geiger
Archivum immunologiae et therapiae experimentalis 58, 335-346, 2010
362010
ARC-8: Phase I/Ib study to evaluate safety and tolerability of AB680+ chemotherapy+ zimberelimab (AB122) in patients with treatment-naive metastatic pancreatic adenocarcinoma …
GA Manji, ZA Wainberg, K Krishnan, N Giafis, A Udyavar, CS Quah, ...
Journal of Clinical Oncology 39 (3_suppl), 404-404, 2021
212021
Genomic alterations associated with recurrence and TNBC subtype in high-risk early breast cancers
TR Wilson, AR Udyavar, CW Chang, JM Spoerke, J Aimi, HM Savage, ...
Molecular Cancer Research 17 (1), 97-108, 2019
182019
Intrinsic and acquired drug resistance to LSD1 inhibitors in small cell lung cancer occurs through a TEAD4‐driven transcriptional state
W Yan, CY Chung, T Xie, M Ozeck, TC Nichols, J Frey, AR Udyavar, ...
Molecular Oncology 16 (6), 1309-1328, 2022
172022
Targeting CD73 with AB680 (quemliclustat), a novel and potent small-molecule CD73 inhibitor, restores immune functionality and facilitates antitumor immunity
D Piovesan, JBL Tan, A Becker, J Banuelos, N Narasappa, D DiRenzo, ...
Molecular Cancer Therapeutics 21 (6), 948-959, 2022
162022
Phase I evaluation of AB928, a novel dual adenosine receptor antagonist, combined with chemotherapy or AB122 (anti-PD-1) in patients (pts) with advanced malignancies
J Powderly, A Spira, R Gutierrez, D DiRenzo, A Udyavar, JJ Karakunnel, ...
Annals of Oncology 30, v493, 2019
152019
Altered TGF-α/β signaling drives cooperation between breast cancer cell populations
OE Franco, DR Tyson, KC Konvinse, AR Udyavar, L Estrada, V Quaranta, ...
The FASEB Journal 30 (10), 3441, 2016
112016
Abstract P2-09-13: molecular characterization of tumors from metastatic TNBC patients treated with atezolizumab (atezo)
L Molinero, CW Chang, A Udyavar, M Fasso, C O'Hear, L Emens, C Cruz, ...
Cancer Research 78 (4_Supplement), P2-09-13-P2-09-13, 2018
92018
Abstract CT129: ARC-3: Updated results of etrumadenant (AB928)+ modified FOLFOX-6 (mFOLFOX-6) in metastatic colorectal cancer (mCRC) patients
M Cecchini, C Quah, S Liu, R Woloski, A Udyavar, M Giannakis
Cancer Research 81 (13_Supplement), CT129-CT129, 2021
62021
Characterization of AB154, a humanized, non-depleting α-TIGIT antibody undergoing clinical evaluation in subjects with advanced solid tumors
AE Anderson, A Lopez, A Udyavar, N Narasappa, S Lee, D DiRenzo, ...
Proceedings of the SITC Annual Meeting, National Harbor, MD, USA, 6-10, 2019
42019
Altered pan-Ras pathway and activating mutations in EGFR result in elevated CD73 in multiple cancers
AR Udyavar, D DiRenzo, D Piovesan, D Ashok, AE Anderson, SW Young, ...
AACR abstract 2526, 2019
42019
Abstract B27: Phenotypic plasticity and heterogeneity in small cell lung cancer (SCLC): Novel molecular subtypes and potential for targeted therapy.
AR Udyavar, M Hoeksema, K Diggins, J Irish, PP Massion, V Quaranta
Clinical Cancer Research 20 (2_Supplement), B27-B27, 2014
42014
Antitumor activity of T cells expressing a novel anti-folate receptor alpha (FOLR1) costimulatory antigen receptor (CoStAR) in a human xenograft murine solid tumor model and …
OR Moon, Y Qu, MG King, M Mojadidi, C Chauvin-Fleurence, C Yarka, ...
Journal of Clinical Oncology 40 (16_suppl), 2535-2535, 2022
32022
Transcriptomic profiling of adjuvant colorectal cancer identifies three key prognostic biological processes and a disease specific role for granzyme B
A Daemen, AR Udyavar, T Sandmann, C Li, LJW Bosch, W O’Gorman, ...
Plos one 16 (12), e0262198, 2021
32021
Correction: Novel Hybrid. Phenotype Revealed in Small Cell Lung Cancer by a Transcription Factor Network Model. That Can Explain Tumor Heterogeneity
AR Udyavar, DJ Wooten, M Hoeksema, M Bansal, A Califano, L Estrada, ...
Cancer Res 79 (1014), 10.1158, 2019
32019
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מאמרים 1–20