| Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress ZT Schug, B Peck, DT Jones, Q Zhang, S Grosskurth, IS Alam, ... Cancer cell 27 (1), 57-71, 2015 | 703 | 2015 |
| Targeting cancer metabolism in the era of precision oncology ZE Stine, ZT Schug, JM Salvino, CV Dang Nature reviews Drug discovery 21 (2), 141-162, 2022 | 466 | 2022 |
| Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate S Zhao, C Jang, J Liu, K Uehara, M Gilbert, L Izzo, X Zeng, S Trefely, ... Nature 579 (7800), 586-591, 2020 | 359 | 2020 |
| Cardiolipin provides an essential activating platform for caspase-8 on mitochondria F Gonzalvez, ZT Schug, RH Houtkooper, ED MacKenzie, DG Brooks, ... The Journal of cell biology 183 (4), 681-696, 2008 | 316 | 2008 |
| Cardiolipin acts as a mitochondrial signalling platform to launch apoptosis ZT Schug, E Gottlieb Biochimica et Biophysica Acta (BBA)-Biomembranes 1788 (10), 2022-2031, 2009 | 297 | 2009 |
| NAD+ metabolism governs the proinflammatory senescence-associated secretome T Nacarelli, L Lau, T Fukumoto, J Zundell, N Fatkhutdinov, S Wu, KM Aird, ... Nature cell biology 21 (3), 397-407, 2019 | 272 | 2019 |
| The metabolic fate of acetate in cancer ZT Schug, J Vande Voorde, E Gottlieb Nature Reviews Cancer 16 (11), 708-717, 2016 | 272 | 2016 |
| Acetate recapturing by nuclear acetyl-CoA synthetase 2 prevents loss of histone acetylation during oxygen and serum limitation V Bulusu, S Tumanov, E Michalopoulou, NJ van den Broek, G MacKay, ... Cell reports 18 (3), 647-658, 2017 | 224 | 2017 |
| Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments B Peck, ZT Schug, Q Zhang, B Dankworth, DT Jones, E Smethurst, ... Cancer & metabolism 4, 1-18, 2016 | 218 | 2016 |
| Cancer metabolism at a glance A Vazquez, JJ Kamphorst, EK Markert, ZT Schug, S Tardito, E Gottlieb Journal of cell science 129 (18), 3367-3373, 2016 | 209 | 2016 |
| BID is cleaved by caspase-8 within a native complex on the mitochondrial membrane ZT Schug, F Gonzalvez, RH Houtkooper, FM Vaz, E Gottlieb Cell Death & Differentiation 18 (3), 538-548, 2011 | 201 | 2011 |
| Unique pattern of neutrophil migration and function during tumor progression S Patel, S Fu, J Mastio, GA Dominguez, A Purohit, A Kossenkov, C Lin, ... Nature immunology 19 (11), 1236-1247, 2018 | 163 | 2018 |
| Polyunsaturated fatty acids from astrocytes activate PPARγ signaling in cancer cells to promote brain metastasis Y Zou, A Watters, N Cheng, CE Perry, K Xu, GM Alicea, JLD Parris, ... Cancer Discovery 9 (12), 1720-1735, 2019 | 115 | 2019 |
| Proteomics-Based Metabolic Modeling Reveals That Fatty Acid Oxidation (FAO) Controls Endothelial Cell (EC) Permeability*[S] F Patella, ZT Schug, E Persi, LJ Neilson, Z Erami, D Avanzato, F Maione, ... Molecular & Cellular Proteomics 14 (3), 621-634, 2015 | 105 | 2015 |
| Changes in aged fibroblast lipid metabolism induce age-dependent melanoma cell resistance to targeted therapy via the fatty acid transporter FATP2 GM Alicea, VW Rebecca, AR Goldman, ME Fane, SM Douglass, ... Cancer discovery 10 (9), 1282-1295, 2020 | 88 | 2020 |
| The role of the S4-S5 linker and C-terminal tail in inositol 1, 4, 5-trisphosphate receptor function ZT Schug, SK Joseph Journal of biological chemistry 281 (34), 24431-24440, 2006 | 83 | 2006 |
| MYC regulates fatty acid metabolism through a multigenic program in claudin-low triple negative breast cancer JC Casciano, C Perry, AJ Cohen-Nowak, KD Miller, J Vande Voorde, ... British journal of cancer 122 (6), 868-884, 2020 | 71 | 2020 |
| The music of lipids: how lipid composition orchestrates cellular behaviour ZT Schug, C Frezza, LCA Galbraith, E Gottlieb Acta oncologica 51 (3), 301-310, 2012 | 61 | 2012 |
| Molecular characterization of the inositol 1, 4, 5-trisphosphate receptor pore-forming segment ZT Schug, PCA da Fonseca, CD Bhanumathy, L Wagner, X Zhang, ... Journal of biological chemistry 283 (5), 2939-2948, 2008 | 58 | 2008 |
| Targeting ACSS2 with a transition-state mimetic inhibits triple-negative breast cancer growth KD Miller, K Pniewski, CE Perry, SB Papp, JD Shaffer, JN Velasco-Silva, ... Cancer research 81 (5), 1252-1264, 2021 | 47 | 2021 |
