Follow
Reggy Ekkebus
Reggy Ekkebus
Verified email at nki.nl
Title
Cited by
Cited by
Year
OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis
TET Mevissen, MK Hospenthal, PP Geurink, PR Elliott, M Akutsu, ...
Cell 154 (1), 169-184, 2013
4552013
Chemical Synthesis of Ubiquitin, Ubiquitin‐Based Probes, and Diubiquitin
F El Oualid, R Merkx, R Ekkebus, DS Hameed, JJ Smit, A de Jong, ...
Angewandte Chemie International Edition 49 (52), 10149-10153, 2010
2742010
On terminal alkynes that can react with active-site cysteine nucleophiles in proteases
R Ekkebus, SI van Kasteren, Y Kulathu, A Scholten, I Berlin, PP Geurink, ...
Journal of the American Chemical Society, 2013
2622013
BAP1/ASXL1 recruitment and activation for H2A deubiquitination
DD Sahtoe, WJ Van Dijk, R Ekkebus, H Ovaa, TK Sixma
Nature communications 7 (1), 1-13, 2016
1362016
Development of a selective ESI-MS derivatization reagent: synthesis and optimization for the analysis of aldehydes in biological mixtures
M Eggink, M Wijtmans, R Ekkebus, H Lingeman, IJP Esch, J Kool, ...
Analytical chemistry 80 (23), 9042-9051, 2008
1122008
Recognition of Lys48-linked di-ubiquitin and deubiquitinating activities of the SARS coronavirus papain-like protease
M Békés, R Ekkebus, H Ovaa, TT Huang, CD Lima
Molecular cell 62 (4), 572-585, 2016
1072016
Mechanism of UCH-L5 activation and inhibition by DEUBAD domains in RPN13 and INO80G
DD Sahtoe, WJ van Dijk, F El Oualid, R Ekkebus, H Ovaa, TK Sixma
Molecular cell 57 (5), 887-900, 2015
982015
Non-hydrolyzable diubiquitin probes reveal linkage-specific reactivity of deubiquitylating enzymes mediated by S2 pockets
D Flierman, R Ekkebus, PP Geurink, TET Mevissen, MK Hospenthal, ...
Cell chemical biology 23 (4), 472-482, 2016
812016
Altered peptide ligands revisited: vaccine design through chemically modified HLA-A2–restricted T cell epitopes
R Hoppes, R Oostvogels, JJ Luimstra, K Wals, M Toebes, L Bies, ...
The Journal of Immunology 193 (10), 4803-4813, 2014
482014
Catching a DUB in the act: novel ubiquitin-based active site directed probes
R Ekkebus, D Flierman, PP Geurink, H Ovaa
Current opinion in chemical biology 23, 63-70, 2014
462014
Dot1 promotes H2B ubiquitination by a methyltransferase-independent mechanism
T van Welsem, T Korthout, R Ekkebus, D Morais, TM Molenaar, ...
Nucleic acids research 46 (21), 11251-11261, 2018
272018
Technologies for MHC class I immunoproteomics
R Hoppes, R Ekkebus, TNM Schumacher, H Ovaa
Journal of proteomics 73 (10), 1945-1953, 2010
222010
Kinetic analysis of multistep USP7 mechanism shows critical role for target protein in activity
RQ Kim, PP Geurink, MPC Mulder, A Fish, R Ekkebus, F El Oualid, ...
Nature communications 10 (1), 1-16, 2019
152019
es, AJ Heck, D. Komander and H. Ovaa
R Ekkebus, SI van Kasteren, Y Kulathu, A Scholten, I Berlin, PP Geurink, ...
J. Am. Chem. Soc 135, 2867-2870, 2013
62013
Cysteine protease capturing agents
H Ovaa, R Ekkebus, SI Van Kasteren, A De Jong, PP Geurink
US Patent App. 14/412,990, 2015
32015
Non-hydrolyzable protein conjugates, methods and compositions related thereto
H Ovaa, A Shanmugham, R Ekkebus, F El Oualid, R Merkx
2011
On terminal alkynes that can react with active-site cysteine nucleophiles in proteases–Supplementary Materials
R Ekkebus, SI van Kasteren, Y Kulathu, A Scholten, I Berlin, AJ Geurink, ...
The system can't perform the operation now. Try again later.
Articles 1–17