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Paul Wilder
Paul Wilder
FDA, Consultant
Verified email at fda.hhs.gov
Title
Cited by
Cited by
Year
Inhibiting S100B restores p53 levels in primary malignant melanoma cancer cells
J Lin, Q Yang, Z Yan, J Markowitz, PT Wilder, F Carrier, DJ Weber
Journal of Biological Chemistry 279 (32), 34071-34077, 2004
1792004
The Ca2+-Dependent Interaction of S100B(ββ) with a Peptide Derived from p53
RR Rustandi, AC Drohat, DM Baldisseri, PT Wilder, DJ Weber
Biochemistry 37 (7), 1951-1960, 1998
1701998
Selective expansion of target cell populations
M Kraus, PT Wilder, J Friberg
US Patent 6,338,942, 2002
1552002
The calcium-binding protein S100B down-regulates p53 and apoptosis in malignant melanoma
J Lin, Q Yang, PT Wilder, F Carrier, DJ Weber
Journal of biological chemistry 285 (35), 27487-27498, 2010
1412010
S100B(ββ) inhibits the protein kinase C‐dependent phosphorylation of a peptide derived from p53 in a Ca2+‐dependent manner
PT Wilder, RR Rustandi, AC Drohat, DJ Weber
Protein Science 7 (3), 794-798, 1998
1171998
Recognition of the tumor suppressor protein p53 and other protein targets by the calcium-binding protein S100B
PT Wilder, J Lin, CL Bair, TH Charpentier, D Yang, M Liriano, KM Varney, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1763 (11), 1284-1297, 2006
1112006
Structure of Ca2+-Bound S100A4 and Its Interaction with Peptides Derived from Nonmuscle Myosin-IIA
VN Malashkevich, KM Varney, SC Garrett, PT Wilder, D Knight, ...
Biochemistry 47 (18), 5111-5126, 2008
1082008
The novel BH3 α-helix mimetic JY-1-106 induces apoptosis in a subset of cancer cells (lung cancer, colon cancer and mesothelioma) by disrupting Bcl-xL and Mcl-1 protein–protein …
X Cao, JL Yap, MK Newell-Rogers, C Peddaboina, W Jiang, ...
Molecular cancer 12, 1-16, 2013
1042013
Selective expansion of target cell populations
M Kraus, PT Wilder, J Friberg
US Patent 5,925,567, 1999
1021999
Relaxation of the rigid backbone of an oligoamide-foldamer-based α-helix mimetic: Identification of potent Bcl-x L inhibitors
JL Yap, X Cao, K Vanommeslaeghe, KY Jung, C Peddaboina, PT Wilder, ...
Organic & Biomolecular Chemistry 10 (15), 2928-2933, 2012
872012
Calcium-binding properties of wild-type and EF-hand mutants of S100B in the presence and absence of a peptide derived from the C-terminal negative regulatory domain of p53
J Markowitz, RR Rustandi, KM Varney, PT Wilder, R Udan, SL Wu, ...
Biochemistry 44 (19), 7305-7314, 2005
762005
Divalent metal ion complexes of S100B in the absence and presence of pentamidine
TH Charpentier, PT Wilder, MA Liriano, KM Varney, E Pozharski, ...
Journal of molecular biology 382 (1), 56-73, 2008
662008
Structure-based design of N-substituted 1-hydroxy-4-sulfamoyl-2-naphthoates as selective inhibitors of the Mcl-1 oncoprotein
ME Lanning, W Yu, JL Yap, J Chauhan, L Chen, E Whiting, LS Pidugu, ...
European journal of medicinal chemistry 113, 273-292, 2016
592016
The Effects of CapZ Peptide (TRTK-12) Binding to S100B–Ca2+ as Examined by NMR and X-ray Crystallography
TH Charpentier, LE Thompson, MA Liriano, KM Varney, PT Wilder, ...
Journal of molecular biology 396 (5), 1227-1243, 2010
592010
Amphipathic α-helix mimetics based on a 1, 2-diphenylacetylene scaffold
KY Jung, K Vanommeslaeghe, ME Lanning, JL Yap, C Gordon, PT Wilder, ...
Organic letters 15 (13), 3234-3237, 2013
552013
The calcium-dependent interaction between S100B and the mitochondrial AAA ATPase ATAD3A and the role of this complex in the cytoplasmic processing of ATAD3A
B Gilquin, BR Cannon, A Hubstenberger, B Moulouel, E Falk, N Merle, ...
Molecular and cellular biology, 2010
552010
Solution structure of S100A1 bound to the CapZ peptide (TRTK12)
NT Wright, BR Cannon, PT Wilder, MT Morgan, KM Varney, DB Zimmer, ...
Journal of molecular biology 386 (5), 1265-1277, 2009
532009
Solution Structure of Zinc- and Calcium-Bound Rat S100B as Determined by Nuclear Magnetic Resonance Spectroscopy,
PT Wilder, KM Varney, MB Weiss, RK Gitti, DJ Weber
Biochemistry 44 (15), 5690-5702, 2005
522005
Location of the Zn2+-Binding Site on S100B As Determined by NMR Spectroscopy and Site-Directed Mutagenesis
PT Wilder, DM Baldisseri, R Udan, KM Vallely, DJ Weber
Biochemistry 42 (46), 13410-13421, 2003
502003
In vitro screening and structural characterization of inhibitors of the S100B-p53 interaction
PT Wilder, TH Charpentier, MA Liriano, K Gianni, KM Varney, E Pozharski, ...
International journal of high throughput screening, 109-126, 2010
432010
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