| Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry Y Ho, A Gruhler, A Heilbut, GD Bader, L Moore, SL Adams, A Millar, ... Nature 415 (6868), 180-183, 2002 | 4607 | 2002 |
| Large‐scale mapping of human protein–protein interactions by mass spectrometry RM Ewing, P Chu, F Elisma, H Li, P Taylor, S Climie, ... Molecular systems biology 3 (1), 89, 2007 | 1238 | 2007 |
| Synergistic drug combinations tend to improve therapeutically relevant selectivity J Lehár, AS Krueger, W Avery, AM Heilbut, LM Johansen, ER Price, ... Nature biotechnology 27 (7), 659-666, 2009 | 981 | 2009 |
| Sequencing chromosomal abnormalities reveals neurodevelopmental loci that confer risk across diagnostic boundaries ME Talkowski, JA Rosenfeld, I Blumenthal, V Pillalamarri, C Chiang, ... Cell 149 (3), 525-537, 2012 | 641 | 2012 |
| Complete reversal of fatal pulmonary hypertension in rats by a serine elastase inhibitor KN Cowan, A Heilbut, T Humpl, C Lam, S Ito, M Rabinovitch Nature medicine 6 (6), 698-702, 2000 | 501 | 2000 |
| Chemical combination effects predict connectivity in biological systems J Lehár, GR Zimmermann, AS Krueger, RA Molnar, JT Ledell, AM Heilbut, ... Molecular systems biology 3 (1), 2007 | 329 | 2007 |
| Complex reorganization and predominant non-homologous repair following chromosomal breakage in karyotypically balanced germline rearrangements and transgenic integration C Chiang, JC Jacobsen, C Ernst, C Hanscom, A Heilbut, I Blumenthal, ... Nature genetics 44 (4), 390-397, 2012 | 283 | 2012 |
| Next-generation sequencing strategies enable routine detection of balanced chromosome rearrangements for clinical diagnostics and genetic research ME Talkowski, C Ernst, A Heilbut, C Chiang, C Hanscom, A Lindgren, ... The American Journal of Human Genetics 88 (4), 469-481, 2011 | 217 | 2011 |
| Functional genomics and proteomics: charting a multidimensional map of the yeast cell GD Bader, A Heilbut, B Andrews, M Tyers, T Hughes, C Boone Trends in cell biology 13 (7), 344-356, 2003 | 161 | 2003 |
| Molecular adaptations of striatal spiny projection neurons during levodopa-induced dyskinesia M Heiman, A Heilbut, V Francardo, R Kulicke, RJ Fenster, ED Kolaczyk, ... Proc Natl Acad Sci U S A 111 (12), 4578-83, 2014 | 115 | 2014 |
| Knocking out multigene redundancies via cycles of sexual assortment and fluorescence selection Y Suzuki, RPS Onge, R Mani, OD King, A Heilbut, VM Labunskyy, ... Nature methods 8 (2), 159-164, 2011 | 94 | 2011 |
| Control of Huntington’s disease-associated phenotypes by the striatum-enriched transcription factor Foxp2 LJ Hachigian, V Carmona, RJ Fenster, R Kulicke, A Heilbut, A Sittler, ... Cell reports 21 (10), 2688-2695, 2017 | 28 | 2017 |
| Yeast proteome analysis G Bader, S Climie, D Durocher, J Figeys, A Gruhler, A Heilbut, Y Ho, ... US Patent App. 10/252,749, 2003 | 26 | 2003 |
| Elastase inhibition induces a smooth muscle cell apoptotic response mediating reversal of progressive pulmonary vascular disease in rats KN Cowan, A Heilbut, T Humpl, M Rabinovitch Circulation 100 (18), 484-484, 1999 | 1 | 1999 |
| Structured clustering representations and methods A Heilbut Boston University, 2016 | | 2016 |
| PRC2 Regulates Transcriptional and Behavioral Phenotypes Induced by Mutant Huntingtin R Fenster, A Heilbut, R Kulicke, A Powers, L Hachigian, M Heiman NEUROPSYCHOPHARMACOLOGY 40, S530-S530, 2015 | | 2015 |
| Dysregulation of Polycomb Repressive Complex 2 (PRC2) Activity in Huntington's Disease RJ Fenster, AM Heilbut, R Kulicke, LJ Hachigian, R Shema, JP Mesirov, ... BIOLOGICAL PSYCHIATRY 77 (9), 413S-413S, 2015 | | 2015 |
| Systematic screening of targeted chemical combinations for cancer therapy A Heilbut, J Lehar, G Short, G Zimmermann, C Keith Cancer Research 67 (9_Supplement), 1410-1410, 2007 | | 2007 |
| Discovering multi-target modulators of cancer networks using high throughput combination screening A Heilbut, S Wise, J Lehár, GR Zimmermann, CT Keith Cancer Research 66 (8_Supplement), 261-261, 2006 | | 2006 |
| Serine elastase inhibitors repress tenascin-C, induce smooth muscle cell apoptosis and reverse advanced pulmonary hypertension KN Cowan, A Heilbut, T Humpl, C Lam, S Ito, M Rabinovitch MOLECULAR BIOLOGY OF THE CELL 10, 66A-66A, 1999 | | 1999 |
Joseph LeharAdjunct Prof, Boston UniversityVerified email at alum.mit.edu
