עקוב אחר
Liu Huolong
Liu Huolong
Senior Engineer, Alexion, AstraZeneca Rare Disease
אין אימייל מאומת
כותרת
צוטט על ידי
צוטט על ידי
שנה
Optimization of critical quality attributes in continuous twin-screw wet granulation via design space validated with pilot scale experimental data
H Liu, SC Galbraith, B Ricart, C Stanton, B Smith-Goettler, L Verdi, ...
International Journal of Pharmaceutics 525 (1), 249-263, 2017
662017
Two-compartmental population balance modeling of a pulsed spray fluidized bed granulation based on computational fluid dynamics (CFD) analysis
H Liu, M Li
International Journal of pharmaceutics 475 (1-2), 256-269, 2014
552014
Using the Box–Behnken experimental design to optimise operating parameters in pulsed spray fluidised bed granulation
H Liu, K Wang, W Schlindwein, M Li
International Journal of Pharmaceutics 448 (2), 329-338, 2013
452013
Media formulation optimization: current and future opportunities
SC Galbraith, H Bhatia, H Liu, S Yoon
Current opinion in chemical engineering 22, 42-47, 2018
392018
Design space determination and process optimization in at-scale continuous twin screw wet granulation
H Liu, B Ricart, C Stanton, B Smith-Goettler, L Verdi, T O'Connor, S Lee, ...
Computers & Chemical Engineering 125, 271-286, 2019
352019
Population balance modelling and multi-stage optimal control of a pulsed spray fluidized bed granulation
H Liu, M Li
International Journal of Pharmaceutics 468 (1-2), 223-233, 2014
292014
Integrated modeling of a continuous direct compression tablet manufacturing process: a production scale case study
SC Galbraith, B Cha, Z Huang, S Park, H Liu, RF Meyer, MH Flamm, ...
Powder technology 354, 199-210, 2019
272019
Linking process variables to residence time distribution in a hybrid flowsheet model for continuous direct compression
SC Galbraith, S Park, Z Huang, H Liu, RF Meyer, M Metzger, MH Flamm, ...
Chemical Engineering Research and Design 153, 85-95, 2020
262020
Prediction of critical quality attributes and optimization of continuous dry granulation process via flowsheet modeling and experimental validation
SY Park, SC Galbraith, H Liu, HW Lee, B Cha, Z Huang, T O'Connor, ...
Powder technology 330, 461-470, 2018
252018
Modeling and simulation of continuous powder blending applied to a continuous direct compression process
SC Galbraith, H Liu, B Cha, SY Park, Z Huang, S Yoon
Pharmaceutical Development and Technology 23 (10), 1097-1107, 2018
212018
Three-dimensional computational fluid dynamics (CFD) study of the gas–particle circulation pattern within a fluidized bed granulator: By full factorial design of fluidization …
H Liu, S Yoon, M Li
Drying Technology 35 (9), 1043-1058, 2017
212017
Assessment of spatial heterogeneity in continuous twin screw wet granulation process using three-compartmental population balance model
H Liu, SC Galbraith, SY Park, B Cha, Z Huang, RF Meyer, MH Flamm, ...
Pharmaceutical development and technology 24 (1), 105-117, 2019
172019
A process optimization strategy of a pulsed-spray fluidized bed granulation process based on predictive three-stage population balance model
H Liu, T O'Connor, S Lee, S Yoon
Powder technology 327, 188-200, 2018
172018
Optimization of the manufacturing process of a complex amphotericin B liposomal formulation using quality by design approach
H Liu, B Rivnay, K Avery, JH Myung, D Kozak, N Landrau, A Nivorozhkin, ...
International Journal of Pharmaceutics 585, 119473, 2020
142020
Flowsheet modeling of a continuous direct compression process
S Yoon, S Galbraith, B Cha, H Liu
Computer Aided Chemical Engineering 41, 121-139, 2018
122018
Development of a three-compartmental population balance model for a continuous twin screw wet granulation process
HL Huolong Liu, Shaun C Galbraith, Seo-Young Park, Bumjoon Cha, Zhuangrong ...
Pharmaceutical development and technology, 1-13, 2018
82018
A thermodynamic balance model for liquid film drying kinetics of a tablet film coating and drying process
B Cha, SC Galbraith, H Liu, SY Park, Z Huang, T O’Connor, S Lee, ...
AAPS PharmSciTech 20, 1-13, 2019
72019
Modeling and control of batch pulsed top-spray fluidized bed granulation
H Liu
De Montfort University, 2014
72014
FLOWSHEET MODELING OF A CONTINUOUS DIRECT COMPRESSION TABLETING PROCESS AT PRODUCTION SCALE
SC Galbraith, Z Huang, B Cha, H Liu, S Hurley, MH Flamm, RJ Meyer, ...
FOCAPO 2017, 2017
62017
Transmission network expansion planning by improved simulated annealing approach
X Liu, H Liu, X Zhang, X Zhao
Sop Transactions on power transmission and smart grid 1 (1), 1-8, 2014
62014
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מאמרים 1–20