Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis SL Spencer, S Gaudet, JG Albeck, JM Burke, PK Sorger Nature 459 (7245), 428-432, 2009 | 1236 | 2009 |
A reference map of the human binary protein interactome K Luck, DK Kim, L Lambourne, K Spirohn, BE Begg, W Bian, R Brignall, ... Nature 580 (7803), 402-408, 2020 | 1048 | 2020 |
Electronic detection of DNA by its intrinsic molecular charge J Fritz, EB Cooper, S Gaudet, PK Sorger, SR Manalis Proceedings of the National Academy of sciences 99 (22), 14142-14146, 2002 | 716 | 2002 |
A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis KA Janes, JG Albeck, S Gaudet, PK Sorger, DA Lauffenburger, MB Yaffe Science 310 (5754), 1646-1653, 2005 | 643 | 2005 |
Fold change of nuclear NF-κB determines TNF-induced transcription in single cells REC Lee, SR Walker, K Savery, DA Frank, S Gaudet Molecular cell 53 (6), 867-879, 2014 | 277 | 2014 |
The response of human epithelial cells to TNF involves an inducible autocrine cascade KA Janes, S Gaudet, JG Albeck, UB Nielsen, DA Lauffenburger, ... Cell 124 (6), 1225-1239, 2006 | 254 | 2006 |
Characterization of PDZ-binding kinase, a mitotic kinase S Gaudet, D Branton, RA Lue Proceedings of the National Academy of Sciences 97 (10), 5167-5172, 2000 | 238 | 2000 |
A Compendium of Signals and Responses Triggered by Prodeath and Prosurvival Cytokines* S S Gaudet, KA Janes, JG Albeck, EA Pace, DA Lauffenburger, PK Sorger Molecular & Cellular Proteomics 4 (10), 1569-1590, 2005 | 215 | 2005 |
Inhibition of KRAS-Driven Tumorigenicity by Interruption of an Autocrine Cytokine Circuit Z Zhu, AR Aref, TJ Cohoon, TU Barbie, Y Imamura, S Yang, SE Moody, ... Cancer discovery 4 (4), 452-465, 2014 | 209 | 2014 |
Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors L Tan, J Wang, J Tanizaki, Z Huang, AR Aref, M Rusan, SJ Zhu, Y Zhang, ... Proceedings of the National Academy of Sciences 111 (45), E4869-E4877, 2014 | 205 | 2014 |
A microfabricated device for subcellular organelle sorting H Lu, S Gaudet, MA Schmidt, KF Jensen Analytical chemistry 76 (19), 5705-5712, 2004 | 161 | 2004 |
Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage SJ Hill, T Rolland, G Adelmant, X Xia, MS Owen, A Dricot, TI Zack, ... Genes & development 28 (17), 1957-1975, 2014 | 160 | 2014 |
Cue-signal-response analysis of TNF-induced apoptosis by partial least squares regression of dynamic multivariate data KA Janes, JR Kelly, S Gaudet, JG Albeck, PK Sorger, DA Lauffenburger Journal of Computational Biology 11 (4), 544-561, 2004 | 141 | 2004 |
Collecting and organizing systematic sets of protein data JG Albeck, G MacBeath, FM White, PK Sorger, DA Lauffenburger, ... Nature reviews Molecular cell biology 7 (11), 803-812, 2006 | 138 | 2006 |
Exploring the contextual sensitivity of factors that determine cell-to-cell variability in receptor-mediated apoptosis S Gaudet, SL Spencer, WW Chen, PK Sorger PLoS computational biology 8 (4), e1002482, 2012 | 113 | 2012 |
Cell stimulus and lysis in a microfluidic device with segmented gas− liquid flow J El-Ali, S Gaudet, A Günther, PK Sorger, KF Jensen Analytical chemistry 77 (11), 3629-3636, 2005 | 112 | 2005 |
The distribution and function of alternatively spliced insertions in hDlg M McLaughlin, R Hale, D Ellston, S Gaudet, RA Lue, A Viel Journal of Biological Chemistry 277 (8), 6406-6412, 2002 | 97 | 2002 |
Lyapunov exponents and phase diagrams reveal multi‐factorial control over TRAIL‐induced apoptosis BB Aldridge, S Gaudet, DA Lauffenburger, PK Sorger Molecular systems biology 7 (1), 553, 2011 | 86 | 2011 |
Systematic calibration of a cell signaling network model KA Kim, SL Spencer, JG Albeck, JM Burke, PK Sorger, S Gaudet, DH Kim BMC bioinformatics 11, 1-14, 2010 | 65 | 2010 |
NF-κB signalling and cell fate decisions in response to a short pulse of tumour necrosis factor REC Lee, MA Qasaimeh, X Xia, D Juncker, S Gaudet Scientific Reports 6 (1), 39519, 2016 | 62 | 2016 |