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Ramesh K. Jha
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Engineering glucose metabolism for enhanced muconic acid production in Pseudomonas putida KT2440
GJ Bentley, N Narayanan, RK Jha, D Salvachúa, JR Elmore, GL Peabody, ...
Metabolic engineering 59, 64-75, 2020
912020
Computational design of a PAK1 binding protein
RK Jha, A Leaver-Fay, S Yin, Y Wu, GL Butterfoss, T Szyperski, ...
Journal of molecular biology 400 (2), 257-270, 2010
912010
Scaling behavior and structure of denatured proteins
F Ding, RK Jha, NV Dokholyan
Structure 13 (7), 1047-1054, 2005
852005
Genome Sequence and Transcriptome Analyses of Chrysochromulina tobin: Metabolic Tools for Enhanced Algal Fitness in the Prominent Order Prymnesiales …
BT Hovde, CR Deodato, HM Hunsperger, SA Ryken, W Yost, RK Jha, ...
PLoS Genetics 11 (9), e1005469, 2015
742015
Engineering an Acinetobacter regulon for biosensing and high-throughput enzyme screening in E. coli via flow cytometry
RK Jha, TL Kern, DT Fox, CE M. Strauss
Nucleic acids research 42 (12), 8150-8160, 2014
662014
Rosetta comparative modeling for library design: engineering alternative inducer specificity in a transcription factor
RK Jha, S Chakraborti, TL Kern, DT Fox, CEM Strauss
Proteins: Structure, Function, and Bioinformatics 83 (7), 1327-1340, 2015
632015
A pangenomic analysis of the Nannochloropsisorganellar genomes reveals novel genetic variations in key metabolic genes
SR Starkenburg, KJ Kwon, RK Jha, C McKay, M Jacobs, O Chertkov, ...
BMC genomics 15, 1-21, 2014
512014
Gene amplification, laboratory evolution, and biosensor screening reveal MucK as a terephthalic acid transporter in Acinetobacter baylyi ADP1
I Pardo, RK Jha, RE Bermel, F Bratti, M Gaddis, E McIntyre, W Michener, ...
Metabolic engineering 62, 260-274, 2020
422020
A protocatechuate biosensor for Pseudomonas putida KT2440 via promoter and protein evolution
RK Jha, JM Bingen, CW Johnson, TL Kern, P Khanna, DS Trettel, ...
Metabolic engineering communications 6, 33-38, 2018
362018
A microbial sensor for organophosphate hydrolysis exploiting an engineered specificity switch in a transcription factor
RK Jha, TL Kern, Y Kim, C Tesar, R Jedrzejczak, A Joachimiak, ...
Nucleic Acids Research 44 (17), 8490-8500, 2016
332016
The mitochondrial and chloroplast genomes of the haptophyte Chrysochromulina tobin contain unique repeat structures and gene profiles
BT Hovde, SR Starkenburg, HM Hunsperger, LD Mercer, CR Deodato, ...
BMC genomics 15, 1-23, 2014
332014
Scintillation Proximity Assay for Inhibitors of Escherichia coli MurG and, Optionally, MraY
S Ravishankar, VP Kumar, B Chandrakala, RK Jha, SM Solapure, ...
Antimicrobial agents and chemotherapy 49 (4), 1410-1418, 2005
282005
Sensor-enabled alleviation of product inhibition in chorismate pyruvate-lyase
RK Jha, N Narayanan, N Pandey, JM Bingen, TL Kern, CW Johnson, ...
ACS synthetic biology 8 (4), 775-786, 2019
242019
An improved Protein G with higher affinity for human/rabbit IgG Fc domains exploiting a computationally designed polar network
RK Jha, T Gaiotto, ARM Bradbury, CEM Strauss
Protein Engineering, Design & Selection 27 (4), 127-134, 2014
242014
A High-Throughput Screening Assay for Simultaneous Selection of Inhibitors of Mycobacterium tuberculosis 1-Deoxy-D-Xylulose-5-Phosphate Synthase (Dxs) or 1 …
V Humnabadkar, RK Jha, N Ghatnekar, SM De Sousa
Journal of Biomolecular Screening 16 (3), 303-312, 2011
182011
3D structure analysis of PAKs: A clue to the rational design for affinity reagents and blockers
RK Jha, CEM Strauss
Cellular Logistics 2 (2), 69-77, 2012
172012
Combined computational design of a zinc binding site and a protein-protein interaction: one open zinc coordination site was not a robust hotspot for de novo ubiquitin binding
BS Der, RK Jha, SM Lewis, PM Thompson, G Guntas, B Kuhlman
Proteins: Structure, Function and Bioinformatics, 2013
162013
Rapid Thermostabilization of Bacillus thuringiensis Serovar Konkukian 97–27 Dehydroshikimate Dehydratase through a Structure-Based Enzyme Design and …
LB Harrington, RK Jha, TL Kern, EN Schmidt, GM Canales, KB Finney, ...
ACS Synthetic Biology 6 (1), 120-129, 2017
152017
Redesign of the PAK1 autoinhibitory domain for enhanced stability and affinity in biosensor applications
RK Jha, YI Wu, JS Zawistowski, C MacNevin, KM Hahn, B Kuhlman
Journal of molecular biology 413 (2), 513-522, 2011
152011
Genome sequence and transcriptome analyses of
BT Hovde, CR Deodato, HM Hunsperger, SA Ryken, W Yost, RK Jha, ...
Chrysochromulina tobin, 2015
102015
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