| Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation SS Metkar, B Wang, M Aguilar-Santelises, SM Raja, L Uhlin-Hansen, ... Immunity 16 (3), 417-428, 2002 | 394 | 2002 |
| Human and mouse granzyme A induce a proinflammatory cytokine response SS Metkar, C Menaa, J Pardo, B Wang, R Wallich, M Freudenberg, S Kim, ... Immunity 29 (5), 720-733, 2008 | 349 | 2008 |
| Protein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligases B Mohapatra, G Ahmad, S Nadeau, N Zutshi, W An, S Scheffe, L Dong, ... Biochimica Et Biophysica Acta (BBA)-Molecular Cell Research 1833 (1), 122-139, 2013 | 234 | 2013 |
| Glycosylphosphatidylinositol anchors of membrane glycoproteins are binding determinants for the channel-forming toxin aerolysin DB Diep, KL Nelson, SM Raja, EN Pleshak, JT Buckley Journal of Biological Chemistry 273 (4), 2355-2360, 1998 | 222 | 1998 |
| Induction of cancer cell death by self-assembling nanostructures incorporating a cytotoxic peptide SM Standley, DJ Toft, H Cheng, S Soukasene, J Chen, SM Raja, V Band, ... Cancer research 70 (8), 3020-3026, 2010 | 210 | 2010 |
| Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis SS Metkar, B Wang, ML Ebbs, JH Kim, YJ Lee, SM Raja, CJ Froelich The Journal of cell biology 160 (6), 875-885, 2003 | 208 | 2003 |
| Heparin enhances the specificity of antithrombin for thrombin and factor Xa independent of the reactive center loop sequence: evidence for an exosite determinant of factor Xa … YJ Chuang, R Swanson, SM Raja, ST Olson Journal of Biological Chemistry 276 (18), 14961-14971, 2001 | 202 | 2001 |
| NF‐κB protects from the lysosomal pathway of cell death N Liu, SM Raja, F Zazzeroni, SS Metkar, R Shah, M Zhang, Y Wang, ... The EMBO journal, 2003 | 154 | 2003 |
| Cytotoxic cell granule-mediated apoptosis: characterization of the macromolecular complex of granzyme B with serglycin SM Raja, B Wang, M Dantuluri, UR Desai, B Demeler, K Spiegel, ... Journal of Biological Chemistry 277 (51), 49523-49530, 2002 | 150 | 2002 |
| The glycosylphosphatidylinositol-anchored surface glycoprotein Thy-1 is a receptor for the channel-forming toxin aerolysin KL Nelson, SM Raja, JT Buckley Journal of Biological Chemistry 272 (18), 12170-12174, 1997 | 126 | 1997 |
| Aberrant trafficking of NSCLC-associated EGFR mutants through the endocytic recycling pathway promotes interaction with Src@ BM Chung, SM Raja, RJ Clubb, C Tu, M George, V Band, H Band BMC cell biology 10, 1-17, 2009 | 97 | 2009 |
| A combination of Trastuzumab and 17-AAG induces enhanced ubiquitinylation and lysosomal pathway-dependent ErbB2 degradation and cytotoxicity in ErbB2-overexpressing breast … SM Raja, RJ Clubb, M Bhattacharyya, M Dimri, H Cheng, W Pan, ... Cancer biology & therapy 7 (10), 1630-1640, 2008 | 84 | 2008 |
| Cytotoxic granule-mediated apoptosis: unraveling the complex mechanism SM Raja, SS Metkar, CJ Froelich Current opinion in Immunology 15 (5), 528-532, 2003 | 83 | 2003 |
| Anticancer activity of Celastrol in combination with ErbB2-targeted therapeutics for treatment of ErbB2-overexpressing breast cancers SM Raja, RJ Clubb, C Ortega-Cava, SH Williams, TA Bailey, L Duan, ... Cancer biology & therapy 11 (2), 263-276, 2011 | 82 | 2011 |
| Lysine 114 of antithrombin is of crucial importance for the affinity and kinetics of heparin pentasaccharide binding V Arocas, SC Bock, S Raja, ST Olson, I Björk Journal of Biological Chemistry 276 (47), 43809-43817, 2001 | 80 | 2001 |
| A novel mechanism for protein delivery: granzyme B undergoes electrostatic exchange from serglycin to target cells SM Raja, SS Metkar, S Honing, B Wang, WA Russin, NH Pipalia, ... Journal of Biological Chemistry 280 (21), 20752-20761, 2005 | 78 | 2005 |
| Localization and environment of tryptophans in soluble and membrane-bound states of a pore-forming toxin from Staphylococcus aureus SM Raja, SS Rawat, A Chattopadhyay, AK Lala Biophysical journal 76 (3), 1469-1479, 1999 | 78 | 1999 |
| Mechanisms of Trastuzumab resistance in ErbB2-driven breast cancer and newer opportunities to overcome therapy resistance TA Bailey, H Luan, RJ Clubb, M Naramura, V Band, SM Raja, H Band Journal of carcinogenesis 10, 2011 | 71 | 2011 |
| The antithrombin P1 residue is important for target proteinase specificity but not for heparin activation of the serpin. Characterization of P1 antithrombin variants with … YJ Chuang, R Swanson, SM Raja, SC Bock, ST Olson Biochemistry 40 (22), 6670-6679, 2001 | 64 | 2001 |
| Granzyme-mediated cytotoxicity does not involve the mannose 6-phosphate receptors on target cells R Dressel, SM Raja, S Höning, T Seidler, CJ Froelich, K von Figura, ... Journal of Biological Chemistry 279 (19), 20200-20210, 2004 | 59 | 2004 |
