Alex Kentsis
Alex Kentsis
Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center
Verified email at - Homepage
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Nedd8 on cullin: building an expressway to protein destruction
ZQ Pan, A Kentsis, DC Dias, K Yamoah, K Wu
Oncogene 23 (11), 1985-1997, 2004
Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA cap
A Kentsis, I Topisirovic, B Culjkovic, L Shao, KLB Borden
Proceedings of the National Academy of Sciences 101 (52), 18105-18110, 2004
PML RING suppresses oncogenic transformation by reducing the affinity of eIF4E for mRNA
N Cohen, M Sharma, A Kentsis, JM Perez, S Strudwick, KLB Borden
The EMBO journal 20 (16), 4547-4559, 2001
The Mdm2 RING domain C‐terminus is required for supramolecular assembly and ubiquitin ligase activity
MV Poyurovsky, C Priest, A Kentsis, KLB Borden, ZQ Pan, N Pavletich, ...
The EMBO journal 26 (1), 90-101, 2007
Autocrine activation of the MET receptor tyrosine kinase in acute myeloid leukemia
A Kentsis, C Reed, KL Rice, T Sanda, SJ Rodig, E Tholouli, A Christie, ...
Nature medicine 18 (7), 1118-1122, 2012
Mechanisms of androgen induction of sebocyte differentiation
RL Rosenfield, D Deplewski, A Kentsis, N Ciletti
Dermatology 196 (1), 43-46, 1998
Trifluoroethanol promotes helix formation by destabilizing backbone exposure: desolvation rather than native hydrogen bonding defines the kinetic pathway of dimeric coiled coil …
A Kentsis, TR Sosnick
Biochemistry 37 (41), 14613-14622, 1998
Phenothiazines induce PP2A-mediated apoptosis in T cell acute lymphoblastic leukemia
A Gutierrez, L Pan, RWJ Groen, F Baleydier, A Kentsis, J Marineau, ...
The Journal of clinical investigation 124 (2), 644-655, 2014
The BCL11B tumor suppressor is mutated across the major molecular subtypes of T-cell acute lymphoblastic leukemia
A Gutierrez, A Kentsis, T Sanda, L Holmfeldt, SC Chen, J Zhang, ...
Blood, The Journal of the American Society of Hematology 118 (15), 4169-4173, 2011
The RING domains of the promyelocytic leukemia protein PML and the arenaviral protein Z repress translation by directly inhibiting translation initiation factor eIF4E
A Kentsis, EC Dwyer, JM Perez, M Sharma, A Chen, ZQ Pan, KLB Borden
Journal of molecular biology 312 (4), 609-623, 2001
Rat preputial sebocyte differentiation involves peroxisome proliferator-activated receptors
RL Rosenfield, A Kentsis, D Deplewski, N Ciletti
Journal of Investigative Dermatology 112 (2), 226-232, 1999
KPT‐330 inhibitor of CRM 1 (XPO 1)‐mediated nuclear export has selective anti‐leukaemic activity in preclinical models of T‐cell acute lymphoblastic leukaemia and acute myeloid …
J Etchin, T Sanda, MR Mansour, A Kentsis, J Montero, BT Le, AL Christie, ...
British journal of haematology 161 (1), 117-127, 2013
Antileukemic activity of nuclear export inhibitors that spare normal hematopoietic cells
J Etchin, Q Sun, A Kentsis, A Farmer, ZC Zhang, T Sanda, MR Mansour, ...
Leukemia 27 (1), 66-74, 2013
Urine proteomics for profiling of human disease using high accuracy mass spectrometry
A Kentsis, F Monigatti, K Dorff, F Campagne, R Bachur, H Steen
PROTEOMICS–Clinical Applications 3 (9), 1052-1061, 2009
Transition state heterogeneity in GCN4 coiled coil folding studied by using multisite mutations and crosslinking
LB Moran, JP Schneider, A Kentsis, GA Reddy, TR Sosnick
Proceedings of the National Academy of Sciences 96 (19), 10699-10704, 1999
Composition and assembly of STAT-targeting ubiquitin ligase complexes: paramyxovirus V protein carboxyl terminus is an oligomerization domain
CM Ulane, A Kentsis, CD Cruz, JP Parisien, KL Schneider, CM Horvath
Journal of virology 79 (16), 10180-10189, 2005
Control of biochemical reactions through supramolecular RING domain self-assembly
A Kentsis, RE Gordon, KLB Borden
Proceedings of the National Academy of Sciences 99 (24), 15404-15409, 2002
Unfolded state of polyalanine is a segmented polyproline II helix
A Kentsis, M Mezei, T Gindin, R Osman
PROTEINS: Structure, Function, and Bioinformatics 55 (3), 493-501, 2004
D/H amide kinetic isotope effects reveal when hydrogen bonds form during protein folding
BA Krantz, LB Moran, A Kentsis, TR Sosnick
Nature structural biology 7 (1), 62-71, 2000
Self-assembly properties of a model RING domain
A Kentsis, RE Gordon, KLB Borden
Proceedings of the National Academy of Sciences 99 (2), 667-672, 2002
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