The power of genetic diversity in genome-wide association studies of lipids SE Graham, SL Clarke, KHH Wu, S Kanoni, GJM Zajac, S Ramdas, ... Nature 600 (7890), 675-679, 2021 | 530 | 2021 |
μABC: a systematic microsecond molecular dynamics study of tetranucleotide sequence effects in B-DNA M Pasi, JH Maddocks, D Beveridge, TC Bishop, DA Case, T Cheatham III, ... Nucleic acids research 42 (19), 12272-12283, 2014 | 221 | 2014 |
Genome-wide association study identifies multiple susceptibility loci for multiple myeloma JS Mitchell, N Li, N Weinhold, A Försti, M Ali, M Van Duin, G Thorleifsson, ... Nature communications 7, 12050, 2016 | 192 | 2016 |
Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis SP Kar, PM Quiros, M Gu, T Jiang, J Mitchell, R Langdon, V Iyer, ... Nature Genetics 54 (8), 1155-1166, 2022 | 176 | 2022 |
Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma M Went, A Sud, A Försti, BM Halvarsson, N Weinhold, S Kimber, ... Nature Communications 9 (1), 2018 | 123 | 2018 |
Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma M Went, A Sud, A Försti, BM Halvarsson, N Weinhold, S Kimber, ... Nature communications 9 (1), 3707, 2018 | 123 | 2018 |
Atomistic simulations reveal bubbles, kinks and wrinkles in supercoiled DNA JS Mitchell, CA Laughton, SA Harris Nucleic acids research 39 (9), 3928-3938, 2011 | 120 | 2011 |
Sequence-dependent persistence lengths of DNA JS Mitchell, J Glowacki, AE Grandchamp, RS Manning, JH Maddocks Journal of chemical theory and computation 13 (4), 1539-1555, 2017 | 114 | 2017 |
Influences of rare protein-coding genetic variants on the human plasma proteome in 50,829 UK Biobank participants RS Dhindsa, OS Burren, BB Sun, BP Prins, D Matelska, E Wheeler, ... bioRxiv, 2022 | 86* | 2022 |
Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer D Jarvis, JS Mitchell, PJ Law, K Palin, S Tuupanen, A Gylfe, UA Hänninen, ... British journal of cancer 115 (2), 266-272, 2016 | 78 | 2016 |
Quantifying the heritability of testicular germ cell tumour using both population-based and genomic approaches K Litchfield, H Thomsen, JS Mitchell, J Sundquist, RS Houlston, ... Scientific reports 5, 13889, 2015 | 71 | 2015 |
Quantifying the heritability of glioma using genome-wide complex trait analysis B Kinnersley, JS Mitchell, K Gousias, J Schramm, A Idbaih, M Labussière, ... Scientific reports 5, 17267, 2015 | 51 | 2015 |
Genome-wide association study identifies variation at 6q25. 1 associated with survival in multiple myeloma DC Johnson, N Weinhold, JS Mitchell, B Chen, M Kaiser, DB Begum, ... Nature communications 7, 2016 | 48 | 2016 |
Genome-wide association study of immunoglobulin light chain amyloidosis in three patient cohorts: comparison with myeloma MI da Silva Filho, A Försti, N Weinhold, I Meziane, C Campo, S Huhn, ... Leukemia, 2016 | 46 | 2016 |
Genome-wide association analysis of chronic lymphocytic leukaemia, Hodgkin lymphoma and multiple myeloma identifies pleiotropic risk loci PJ Law, A Sud, JS Mitchell, M Henrion, G Orlando, O Lenive, P Broderick, ... Scientific reports 7, 41071, 2017 | 44 | 2017 |
Multiple myeloma risk variant at 7p15. 3 creates an IRF4-binding site and interferes with CDCA7L expression N Li, DC Johnson, N Weinhold, JB Studd, G Orlando, F Mirabella, ... Nature communications 7, 13656, 2016 | 44 | 2016 |
Rare variant associations with plasma protein levels in the UK Biobank RS Dhindsa, OS Burren, BB Sun, BP Prins, D Matelska, E Wheeler, ... Nature 622 (7982), 339-347, 2023 | 42 | 2023 |
Insights for precision oncology from the integration of genomic and clinical data of 13,880 tumors from the 100,000 Genomes Cancer Programme A Sosinsky, J Ambrose, W Cross, C Turnbull, S Henderson, L Jones, ... Nature Medicine 30 (1), 279-289, 2024 | 41 | 2024 |
Simulations of DNA topoisomerase 1B bound to supercoiled DNA reveal changes in the flexibility pattern of the enzyme and a secondary protein–DNA binding site I D'annessa, A Coletta, T Sutthibutpong, J Mitchell, G Chillemi, S Harris, ... Nucleic acids research 42 (14), 9304-9312, 2014 | 33 | 2014 |
Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis S Kanoni, SE Graham, Y Wang, I Surakka, S Ramdas, X Zhu, SL Clarke, ... Genome biology 23 (1), 268, 2022 | 32 | 2022 |