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Brian Hemmings
Brian Hemmings
Retired researcher
Verified email at fmi.ch - Homepage
Title
Cited by
Cited by
Year
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
DAE Cross, DR Alessi, P Cohen, M Andjelkovich, BA Hemmings
Nature 378 (6559), 785-789, 1995
66421995
Mechanism of activation of protein kinase B by insulin and IGF‐1.
DR Alessi, M Andjelkovic, B Caudwell, P Cron, N Morrice, P Cohen, ...
The EMBO journal 15 (23), 6541-6551, 1996
39141996
Ten years of protein kinase B signalling: a hard Akt to follow
DP Brazil, BA Hemmings
Trends in biochemical sciences 26 (11), 657-664, 2001
16182001
The lipid phosphatase activity of PTEN is critical for its tumor supressor function
MP Myers, I Pass, IH Batty, J Van der Kaay, JP Stolarov, BA Hemmings, ...
Proceedings of the National Academy of Sciences 95 (23), 13513-13518, 1998
15711998
Role of translocation in the activation and function of protein kinase B
M Andjelkovic, DR Alessi, R Meier, A Fernandez, NJC Lamb, M Frech, ...
Journal of Biological Chemistry 272 (50), 31515-31524, 1997
13791997
Pi3k-pkb/akt pathway
BA Hemmings, DF Restuccia
Cold Spring Harbor perspectives in biology 4 (9), a011189, 2012
12902012
Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways
JC Clemens, CA Worby, N Simonson-Leff, M Muda, T Maehama, ...
Proceedings of the National Academy of Sciences 97 (12), 6499-6503, 2000
11632000
Phosphorylation and activation of p70s6k by PDK1
N Pullen, PB Dennis, M Andjelkovic, A Dufner, SC Kozma, BA Hemmings, ...
Science 279 (5351), 707-710, 1998
10931998
Advances in protein kinase B signalling: AKTion on multiple fronts
DP Brazil, ZZ Yang, BA Hemmings
Trends in biochemical sciences 29 (5), 233-242, 2004
10902004
Structure, regulation and function of PKB/AKT—a major therapeutic target
M Hanada, J Feng, BA Hemmings
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1697 (1-2), 3-16, 2004
10832004
Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)
A Brunet, J Park, H Tran, LS Hu, BA Hemmings, ME Greenberg
Molecular and cellular biology, 2001
10752001
Regulation of protein kinase cascades by protein phosphatase 2A
TA Millward, S Zolnierowicz, BA Hemmings
Trends in biochemical sciences 24 (5), 186-191, 1999
10131999
Serine/threonine protein phosphatases.
S Wera, BA Hemmings
Biochemical Journal 311 (Pt 1), 17, 1995
9091995
Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase
DR Alessi, FB Caudwell, M Andjelkovic, BA Hemmings, P Cohen
FEBS letters 399 (3), 333-338, 1996
8861996
Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily.
PF Jones, T Jakubowicz, FJ Pitossi, F Maurer, BA Hemmings
Proceedings of the National Academy of Sciences 88 (10), 4171-4175, 1991
7911991
PKB binding proteins: getting in on the Akt
DP Brazil, J Park, BA Hemmings
Cell 111 (3), 293-303, 2002
7242002
Pleckstrin domain homology
RJ Haslam, HB Koide, BA Hemmings
Nature 363 (6427), 309-310, 1993
7081993
Serum and glucocorticoid‐inducible kinase (SGK) is a target of the PI 3‐kinase‐stimulated signaling pathway
J Park, MLL Leong, P Buse, AC Maiyar, GL Firestone, BA Hemmings
The EMBO journal, 1999
6921999
Identification of a PKB/Akt Hydrophobic Motif Ser-473 Kinase as DNA-dependent Protein Kinase*♦
J Feng, J Park, P Cron, D Hess, BA Hemmings
Journal of Biological Chemistry 279 (39), 41189-41196, 2004
6832004
Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors.
M Andjelković, T Jakubowicz, P Cron, XF Ming, JW Han, BA Hemmings
Proceedings of the National Academy of Sciences 93 (12), 5699-5704, 1996
6701996
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