| Actin and α-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner CK Choi*, M Vicente-Manzanares*, J Zareno, LA Whitmore, A Mogilner, ... Nature cell biology 10 (9), 1039-1050, 2008 | 1051 | 2008 |
| Integrins in cell migration–the actin connection M Vicente-Manzanares, CK Choi, AR Horwitz Journal of cell science 122 (2), 199-206, 2009 | 619 | 2009 |
| Biomimetic model to reconstitute angiogenic sprouting morphogenesis in vitro DHT Nguyen*, SC Stapleton*, MT Yang, SS Cha, CK Choi, PA Galie, ... Proceedings of the National Academy of Sciences 110 (17), 6712-6717, 2013 | 537 | 2013 |
| Regulation of protrusion, adhesion dynamics, and polarity by myosins IIA and IIB in migrating cells M Vicente-Manzanares, J Zareno, L Whitmore, CK Choi, AF Horwitz The Journal of cell biology 176 (5), 573-580, 2007 | 510 | 2007 |
| Fluid shear stress threshold regulates angiogenic sprouting PA Galie, DHT Nguyen, CK Choi, DM Cohen, PA Janmey, CS Chen Proceedings of the National Academy of Sciences 111 (22), 7968-7973, 2014 | 438 | 2014 |
| Multidimensional traction force microscopy reveals out-of-plane rotational moments about focal adhesions WR Legant*, CK Choi*, JS Miller, L Shao, L Gao, E Betzig, CS Chen Proceedings of the National Academy of Sciences 110 (3), 881-886, 2013 | 331 | 2013 |
| Matrix degradability controls multicellularity of 3D cell migration B Trappmann*, BM Baker*, WJ Polacheck, CK Choi, JA Burdick, CS Chen Nature communications 8 (1), 371, 2017 | 272 | 2017 |
| A DNA-based molecular probe for optically reporting cellular traction forces BL Blakely, CE Dumelin, B Trappmann, LM McGregor, CK Choi, ... Nature methods 11 (12), 1229, 2014 | 232 | 2014 |
| Stoichiometry of molecular complexes at adhesions in living cells MA Digman, PW Wiseman, C Choi, AR Horwitz, E Gratton Proceedings of the National Academy of Sciences 106 (7), 2170-2175, 2009 | 198 | 2009 |
| Extracellular matrix alignment dictates the organization of focal adhesions and directs uniaxial cell migration WY Wang, AT Pearson, ML Kutys, CK Choi, MA Wozniak, BM Baker, ... APL bioengineering 2 (4), 2018 | 109 | 2018 |
| Cross-correlated fluctuation analysis reveals phosphorylation-regulated paxillin-FAK complexes in nascent adhesions CK Choi, J Zareno, MA Digman, E Gratton, AR Horwitz Biophysical Journal 100 (3), 583, 2011 | 107 | 2011 |
| Rac1 is deactivated at integrin activation sites through an IQGAP1–filamin-A–RacGAP1 pathway G Jacquemet, MR Morgan, A Byron, JD Humphries, CK Choi, CS Chen, ... Journal of cell science 126 (18), 4121-4135, 2013 | 89 | 2013 |
| A proteomic approach reveals integrin activation state-dependent control of microtubule cortical targeting A Byron, JA Askari, JD Humphries, G Jacquemet, EJ Koper, S Warwood, ... Nature communications 6 (1), 6135, 2015 | 82 | 2015 |
| Engineered materials and the cellular microenvironment: a strengthening interface between cell biology and bioengineering CK Choi, MT Breckenridge, CS Chen Trends in cell biology 20 (12), 705-714, 2010 | 75 | 2010 |
| Stochastic model of integrin-mediated signaling and adhesion dynamics at the leading edges of migrating cells M Cirit, M Krajcovic, CK Choi, ES Welf, AF Horwitz, JM Haugh PLoS computational biology 6 (2), e1000688, 2010 | 73 | 2010 |
| Tensin1 requires protein phosphatase-1α in addition to RhoGAP DLC-1 to control cell polarization, migration, and invasion EH Hall, AE Daugherty, CK Choi, AF Horwitz, DL Brautigan Journal of Biological Chemistry 284 (50), 34713-34722, 2009 | 65 | 2009 |
| Myosin IIA–mediated forces regulate multicellular integrity during vascular sprouting C Yoon*, CK Choi*, S Stapleton*, T Mirabella, C Howes, L Dong, J King, ... Molecular biology of the cell 30 (16), 1974-1984, 2019 | 30 | 2019 |
| Short-term shear stress induces rapid actin dynamics in living endothelial cells CK Choi, BP Helmke Molecular & cellular biomechanics: MCB 5 (4), 247, 2008 | 26 | 2008 |
| Applications of microphysiological systems to disease models in the biopharmaceutical industry: opportunities and challenges O Irrechukwu, R Yeager, R David, J Ekert, A Saravanakumar, CK Choi ALTEX-Alternatives to animal experimentation 40 (3), 485-518, 2023 | 11 | 2023 |
| Assessment of a 3D neural spheroid model to detect pharmaceutical-induced neurotoxicity Q Wang, JD Cohen, T Yukawa, H Estrella, C Leonard, J Nunes, C Choi, ... ALTEX-Alternatives to animal experimentation, 2022 | 10 | 2022 |
Christopher S. Chen, M.D., Ph.D.Biomedical Engineering, Boston University; The Wyss Institute for Biologically Inspired EngineeringVerified email at bu.edu
