| CAPN5 mutation in hereditary uveitis: the R243L mutation increases calpain catalytic activity and triggers intraocular inflammation in a mouse model KJ Wert, AG Bassuk, WH Wu, L Gakhar, D Coglan, MA Mahajan, S Wu, ... Human molecular genetics 24 (16), 4584-4598, 2015 | 44 | 2015 |
| Structural insights into the unique activation mechanisms of a non-classical calpain and its disease-causing variants G Velez, YJ Sun, S Khan, J Yang, J Herrmann, T Chemudupati, ... Cell reports 30 (3), 881-892. e5, 2020 | 19 | 2020 |
| Whole-exome sequencing of patients with posterior segment uveitis AS Li, G Velez, B Darbro, MA Toral, J Yang, SH Tsang, PJ Ferguson, ... American journal of ophthalmology 221, 246-259, 2021 | 15 | 2021 |
| An intravitreal implant injection method for sustained drug delivery into mouse eyes YJ Sun, CH Lin, MR Wu, SH Lee, J Yang, CR Kunchur, EM Mujica, ... Cell reports methods 1 (8), 2021 | 14 | 2021 |
| Proteomic analysis of intermediate uveitis suggests myeloid cell recruitment and implicates IL-23 as a therapeutic target YJ Sepah, G Velez, PH Tang, J Yang, T Chemudupati, AS Li, QD Nguyen, ... American journal of ophthalmology case reports 18, 100646, 2020 | 14 | 2020 |
| Proteomic insight into the pathogenesis of CAPN5-vitreoretinopathy G Velez, J Yang, AS Li, SH Tsang, AG Bassuk, VB Mahajan Scientific reports 9 (1), 7608, 2019 | 14 | 2019 |
| Small-angle X-ray scattering of calpain-5 reveals a highly open conformation among calpains L Gakhar, AG Bassuk, G Velez, S Khan, J Yang, SH Tsang, VB Mahajan Journal of structural biology 196 (3), 309-318, 2016 | 13 | 2016 |
| A genome-wide CRISPR screen identifies CALCOCO2 as a regulator of beta cell function influencing type 2 diabetes risk AK Rottner, Y Ye, E Navarro-Guerrero, V Rajesh, A Pollner, RJ Bevacqua, ... Nature Genetics 55 (1), 54-65, 2023 | 10 | 2023 |
| Novel REEP6 gene mutation associated with autosomal recessive retinitis pigmentosa Y Lin, CL Xu, G Velez, J Yang, AJ Tanaka, MP Breazzano, VB Mahajan, ... Documenta Ophthalmologica 140, 67-75, 2020 | 6 | 2020 |
| Novel mutations in the 3-box motif of the BACK domain of KLHL7 associated with nonsyndromic autosomal dominant retinitis pigmentosa JK Oh, JR Lima de Carvalho, YJ Sun, S Ragi, J Yang, SR Levi, J Ryu, ... Orphanet journal of rare diseases 14, 1-10, 2019 | 4 | 2019 |
| A protocol to inject ocular drug implants into mouse eyes CH Lin, YJ Sun, SH Lee, EM Mujica, CR Kunchur, MR Wu, J Yang, ... STAR protocols 3 (1), 101143, 2022 | 3 | 2022 |
| Zmiz1 is required for mature β-cell function and mass expansion upon high fat feeding TA Alghamdi, NAJ Krentz, N Smith, AF Spigelman, V Rajesh, A Jha, ... Molecular Metabolism 66, 101621, 2022 | 1 | 2022 |
| Crystal structure of the human calpain-5 catalytic core G Velez, L Gakhar, S Khan, HJ Koster, J Yang, SH Tsang, AG Bassuk, ... Acta crystallographica. Section A, Foundations and advances 73 (a1), a31-a32, 2017 | | 2017 |
