Structural conversion of neurotoxic amyloid-β1–42 oligomers to fibrils M Ahmed, J Davis, D Aucoin, T Sato, S Ahuja, S Aimoto, JI Elliott, ... Nature structural & molecular biology 17 (5), 561-567, 2010 | 1287 | 2010 |
High-resolution atomic force microscopy of soluble Aβ42 oligomers IA Mastrangelo, M Ahmed, T Sato, W Liu, C Wang, P Hough, SO Smith Journal of molecular biology 358 (1), 106-119, 2006 | 304 | 2006 |
Inhibitors of amyloid toxicity based on β-sheet packing of Aβ40 and Aβ42 T Sato, P Kienlen-Campard, M Ahmed, W Liu, H Li, JI Elliott, S Aimoto, ... Biochemistry 45 (17), 5503-5516, 2006 | 249 | 2006 |
An amphipathic motif at the transmembrane-cytoplasmic junction prevents autonomous activation of the thrombopoietin receptor J Staerk, C Lacout, T Sato, SO Smith, W Vainchenker, SN Constantinescu Blood 107 (5), 1864-1871, 2006 | 195 | 2006 |
Amyloidogenic processing but not amyloid precursor protein (APP) intracellular C-terminal domain production requires a precisely oriented APP dimer assembled by transmembrane … P Kienlen-Campard, B Tasiaux, J Van Hees, M Li, S Huysseune, T Sato, ... Journal of Biological Chemistry 283 (12), 7733-7744, 2008 | 167 | 2008 |
A helix-to-coil transition at the ε-cut site in the transmembrane dimer of the amyloid precursor protein is required for proteolysis T Sato, T Tang, G Reubins, JZ Fei, T Fujimoto, P Kienlen-Campard, ... Proceedings of the National Academy of Sciences 106 (5), 1421-1426, 2009 | 141 | 2009 |
Electron microscopic investigations of the adrenal cortex M NISHIKAWA, I MURONE, T SATO Endocrinology 72 (2), 197-209, 1963 | 121 | 1963 |
Rational Design and Identification of a Non‐Peptidic Aggregation Inhibitor of Amyloid‐β Based on a Pharmacophore Motif Obtained from cyclo[‐Lys‐Leu‐Val‐Phe … T Arai, T Araya, D Sasaki, A Taniguchi, T Sato, Y Sohma, M Kanai Angewandte Chemie International Edition 53 (31), 8236-8239, 2014 | 92 | 2014 |
A Cyclic KLVFF-Derived Peptide Aggregation Inhibitor Induces the Formation of Less Toxic Off-Pathway Amyloid-β Oligomers YSMK Tadamasa Arai, Daisuke Sasaki, Takushi Araya, Takeshi Sato ChemBioChem, 2014 | 91 | 2014 |
Tryptophan at the transmembrane–cytosolic junction modulates thrombopoietin receptor dimerization and activation JP Defour, M Itaya, V Gryshkova, IC Brett, C Pecquet, T Sato, SO Smith, ... Proceedings of the National Academy of Sciences 110 (7), 2540-2545, 2013 | 87 | 2013 |
Transmembrane helix orientation influences membrane binding of the intracellular juxtamembrane domain in Neu receptor peptides C Matsushita, H Tamagaki, Y Miyazawa, S Aimoto, SO Smith, T Sato Proceedings of the National Academy of Sciences 110 (5), 1646-1651, 2013 | 82 | 2013 |
Synthesis of the C‐terminal region of opioid receptor like 1 in an SDS micelle by the native chemical ligation: effect of thiol additive and SDS concentration on … T Sato, Y Saito, S Aimoto Journal of peptide science: an official publication of the European Peptide …, 2005 | 77 | 2005 |
Structure of the Membrane Reconstituted Transmembrane−Juxtamembrane Peptide EGFR(622−660) and Its Interaction with Ca2+/Calmodulin T Sato, P Pallavi, U Golebiewska, S McLaughlin, SO Smith Biochemistry 45 (42), 12704-12714, 2006 | 61 | 2006 |
Cooperative roles of hydrophilic loop 1 and the C-terminus of presenilin 1 in the substrate-gating mechanism of γ-secretase S Takagi-Niidome, T Sasaki, S Osawa, T Sato, K Morishima, T Cai, ... Journal of Neuroscience 35 (6), 2646-2656, 2015 | 58 | 2015 |
Synthesis of peptide thioesters via an N–S acyl shift reaction under mild acidic conditions on an N‐4,5‐dimethoxy‐2‐mercaptobenzyl auxiliary group K Nakamura, T Kanao, T Uesugi, T Hara, T Sato, T Kawakami, S Aimoto Journal of Peptide Science: An Official Publication of the European Peptide …, 2009 | 44 | 2009 |
Lipid-protein interplay in dimerization of juxtamembrane domains of epidermal growth factor receptor R Maeda, T Sato, K Okamoto, M Yanagawa, Y Sako Biophysical journal 114 (4), 893-903, 2018 | 36 | 2018 |
His499 regulates dimerization and prevents oncogenic activation by asparagine mutations of the human thrombopoietin receptor E Leroy, JP Defour, T Sato, S Dass, V Gryshkova, MM Shwe, J Staerk, ... Journal of Biological Chemistry 291 (6), 2974-2987, 2016 | 36 | 2016 |
High-resolution 1H MAS RFDR NMR of biological membranes D Aucoin, D Camenares, X Zhao, J Jung, T Sato, SO Smith Journal of Magnetic Resonance 197 (1), 77-86, 2009 | 31 | 2009 |
Synthesis of a membrane protein with two transmembrane regions T Sato, T Kawakami, K Akaji, H Konishi, K Mochizuki, T Fujiwara, ... Journal of Peptide Science: An Official Publication of the European Peptide …, 2002 | 30 | 2002 |
Coupling of transmembrane helix orientation to membrane release of the juxtamembrane region in FGFR3 H Tamagaki, Y Furukawa, R Yamaguchi, H Hojo, S Aimoto, SO Smith, ... Biochemistry 53 (30), 5000-5007, 2014 | 27 | 2014 |