| Therapeutic implication of L-phenylalanine aggregation mechanism and its modulation by D-phenylalanine in phenylketonuria V Singh, RK Rai, A Arora, N Sinha, AK Thakur Scientific reports 4 (1), 3875, 2014 | 123 | 2014 |
| Understanding the self-assembly of Fmoc–phenylalanine to hydrogel formation V Singh, K Snigdha, C Singh, N Sinha, AK Thakur Soft Matter 11 (26), 5353-5364, 2015 | 102 | 2015 |
| Zinc promotes liquid–liquid phase separation of tau protein V Singh, L Xu, S Boyko, K Surewicz, WK Surewicz Journal of Biological Chemistry 295 (18), 5850-5856, 2020 | 88 | 2020 |
| Fmoc-phenylalanine displays antibacterial activity against gram-positive bacteria in gel and solution phases AY Gahane, P Ranjan, V Singh*, RK Sharma, N Sinha, M Sharma, ... Soft Matter, DOI: 10.1039/C7SM02317K, 2018 | 83 | 2018 |
| Glycogen synthase protects neurons from cytotoxicity of mutant huntingtin by enhancing the autophagy flux A Rai, PK Singh, V Singh, V Kumar, R Mishra, AK Thakur, A Mahadevan, ... Cell Death & Disease 9, Article number: 201, 2018 | 31 | 2018 |
| Biodegradable nanoparticles containing mechanism based peptide inhibitors reduce polyglutamine aggregation in cell models and alleviate motor symptoms in a Drosophila model of … AS Joshi, V Singh, A Gahane, AK Thakur ACS Chemical Neuroscience 10 (3), 1603-1614, 2018 | 30 | 2018 |
| Development of mechanism-based antibacterial synergy between Fmoc-phenylalanine hydrogel and aztreonam AY Gahane, V Singh, A Kumar, AK Thakur Biomaterials science 8 (7), 1996-2006, 2020 | 24 | 2020 |
| Discovery of arginine ethyl ester as polyglutamine aggregation inhibitor: conformational transitioning of huntingtin N-terminus augments aggregation suppression V Singh, KA Patel, RK Sharma, PR Patil, AS Joshi, R Parihar, ... ACS Chemical Neuroscience 10 (9), 3969-3985, 2019 | 15 | 2019 |
| NMR Spectroscopy-based Metabolomics of Drosophila Model of Huntington’s Disease Suggests Altered Cell Energetics V Singh, RK Sharma, T Athilingam, P Sinha, N Sinha, AK Thakur Journal of Proteome Research 16 (10), 3863-3872, 2017 | 15 | 2017 |
| Antibiofilm activity of Fmoc-phenylalanine against Gram-positive and Gram-negative bacterial biofilms H Singh, A Gahane, V Singh, S Ghosh, A Thakur The Journal of Antibiotics 74 (6), 407-416, 2021 | 13 | 2021 |
| O-GlcNAc modification forces the formation of an α-Synuclein amyloid-strain with notably diminished seeding activity and pathology AT Balana, AL Mahul-Mellier, BA Nguyen, M Horvath, A Javed, ER Hard, ... Biorxiv, 2023 | 10 | 2023 |
| A revised mechanism for (p) ppGpp synthesis by Rel proteins: the critical role of the 2′-OH of GTP PR Patil, N Vithani, V Singh, A Kumar, B Prakash Journal of Biological Chemistry 295 (37), 12851-12867, 2020 | 7 | 2020 |
| A Drosophila model of oral peptide therapeutics for adult Intestinal Stem Cell tumors A Bajpai, QT Ahmad, HW Tang, N Manzar, V Singh, A Thakur, B Ateeq, ... Disease Models & Mechanisms, doi: 10.1242/dmm.044420, 2020 | 6 | 2020 |
| Osmolytes modulate polyglutamine aggregation in a sequence dependent manner I Saha, V Singh, G Burra, AK Thakur Journal of Peptide Science 24 (8-9), e3115, 2018 | 6 | 2018 |
| Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy BA Nguyen, V Singh, S Afrin, A Yakubovska, L Wang, Y Ahmed, ... Nature communications 15 (1), 1-12, 2024 | 4 | 2024 |
| Structural polymorphism of amyloid fibrils in cardiac ATTR amyloidosis revealed by cryo-electron microscopy LS Binh A. Nguyen, Shumaila Afrin, Virender Singh, Yasmin Ahmed, Rose ... bioRxiv, 2022 | 4 | 2022 |
| Fluorescence correlation spectroscopy as a tool to investigate the directionality of proteolysis B Sengupta, N Das, V Singh, AK Thakur, P Sen International Journal of Biological Macromolecules 164, 2524-2534, 2020 | 4 | 2020 |
| Calmidazolium chloride and its complex with serum albumin prevent Huntingtin exon1 aggregation V Singh, RNV Krishna Deepak, B Sengupta, AS Joshi, H Fan, P Sen, ... Molecular pharmaceutics 15 (8), 3356-3368, 2018 | 3 | 2018 |
| Optimization of Ion-Dependent Green Synthesis of Fmoc-Amino Acids in Phosphate Buffer V Singh, RK Sharma, N Sinha, AK Thakur ChemistrySelect 2 (35), 11826-11831, 2017 | 2 | 2017 |
| Abstract 1610 Leveraging the structures of transthyretin fibrils to understand and detect protein aggregation in ATTR amyloidosis LS Gomez, R Pedretti, B Nguyen, S Afrin, V Singh, MCF Ramirez, P Singh, ... Journal of Biological Chemistry 300 (3), 2024 | | 2024 |
Ashwani Kumar ThakurBiological Sciences and Bioengineering Department, Indian Institute of Technology, Kanpur UP-IndiaVerified email at iitk.ac.in
