| Discrete functions of nuclear receptor Rev-erbα couple metabolism to the clock Y Zhang, B Fang, MJ Emmett, M Damle, Z Sun, D Feng, SM Armour, ... Science 348 (6242), 1488-1492, 2015 | 304 | 2015 |
| Deacetylase-independent function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor Z Sun, D Feng, B Fang, SE Mullican, SH You, HW Lim, LJ Everett, ... Molecular cell 52 (6), 769-782, 2013 | 245 | 2013 |
| Circadian enhancers coordinate multiple phases of rhythmic gene transcription in vivo B Fang, LJ Everett, J Jager, E Briggs, SM Armour, D Feng, A Roy, ... Cell 159 (5), 1140-1152, 2014 | 219 | 2014 |
| Diet-induced circadian enhancer remodeling synchronizes opposing hepatic lipid metabolic processes D Guan, Y Xiong, PC Borck, C Jang, PT Doulias, R Papazyan, B Fang, ... Cell 174 (4), 831-842. e12, 2018 | 154 | 2018 |
| Genetic Variation Determines PPARγ Function and Anti-diabetic Drug Response In Vivo LMA Soccio RE, Chen ER, Rajapurkar SR, Safabakhsh P, Marinis JM, Dispirito ... cell 162 (1), 33-44, 2015 | 128 | 2015 |
| Identification of a binding motif specific to HNF4 by comparative analysis of multiple nuclear receptors B Fang, D Mane-Padros, E Bolotin, T Jiang, FM Sladek Nucleic Acids Research 40 (12), 5343-5356, 2012 | 124 | 2012 |
| Dissociation of muscle insulin sensitivity from exercise endurance in mice by HDAC3 depletion S Hong, W Zhou, B Fang, W Lu, E Loro, M Damle, G Ding, J Jager, ... Nature Medicine, 2016 | 97 | 2016 |
| Stimulus-cleavable chemistry in the field of controlled drug delivery Y Xue, H Bai, B Peng, B Fang, J Baell, L Li, W Huang, NH Voelcker Chemical Society Reviews 50 (8), 4872-4931, 2021 | 94 | 2021 |
| Tropifexor‐mediated abrogation of steatohepatitis and fibrosis is associated with the antioxidative gene expression profile in rodents ED Hernandez, L Zheng, Y Kim, B Fang, B Liu, RA Valdez, WF Dietrich, ... Hepatology communications 3 (8), 1085-1097, 2019 | 83 | 2019 |
| Behavioral changes and dopaminergic dysregulation in mice lacking the nuclear receptor Rev-erbα J Jager, WT O'Brien, J Manlove, EN Krizman, B Fang, Z Gerhart-Hines, ... Molecular endocrinology 28 (4), 490-498, 2014 | 80 | 2014 |
| Structural and kinetic analysis of caspase-3 reveals role for s5 binding site in substrate recognition B Fang, PI Boross, J Tozser, IT Weber Journal of molecular biology 360 (3), 654-666, 2006 | 73 | 2006 |
| The hepatic circadian clock fine-tunes the lipogenic response to feeding through RORα/γ Y Zhang, R Papazyan, M Damle, B Fang, J Jager, D Feng, LC Peed, ... Genes & Development 31 (12), 1202-1211, 2017 | 70 | 2017 |
| Plasticity of S2–S4 specificity pockets of executioner caspase‐7 revealed by structural and kinetic analysis J Agniswamy, B Fang, IT Weber The FEBS Journal 274 (18), 4752-4765, 2007 | 64 | 2007 |
| Differential effects of hepatocyte nuclear factor 4α isoforms on tumor growth and T-cell factor 4/AP-1 interactions in human colorectal cancer cells LM Vuong, K Chellappa, JM Dhahbi, JR Deans, B Fang, E Bolotin, ... Molecular and cellular biology 35 (20), 3471-3490, 2015 | 62 | 2015 |
| HNF6 and Rev-erbα integrate hepatic lipid metabolism by overlapping and distinct transcriptional mechanisms Y Zhang, B Fang, M Damle, D Guan, Z Li, YH Kim, M Gannon, MA Lazar Genes & development 30 (14), 1636-1644, 2016 | 59 | 2016 |
| Structural basis for executioner caspase recognition of P5 position in substrates G Fu, AA Chumanevich, J Agniswamy, B Fang, RW Harrison, IT Weber Apoptosis 13 (11), 1291-1302, 2008 | 40 | 2008 |
| Caspase-3 binds diverse P4 residues in peptides as revealed by crystallography and structural modeling B Fang, G Fu, J Agniswamy, RW Harrison, IT Weber Apoptosis 14 (5), 741-752, 2009 | 37 | 2009 |
| The nuclear receptor Rev-erbα regulates adipose tissue-specific FGF21 signaling J Jager, F Wang, B Fang, HW Lim, LC Peed, DJ Steger, KJ Won, ... Journal of Biological Chemistry 291 (20), 10867-10875, 2016 | 36 | 2016 |
| Genetic backgrounds determine brown remodeling of white fat in rodents G Ferrannini, M Namwanje, B Fang, M Damle, D Li, Q Liu, MA Lazar, ... Molecular metabolism 5 (10), 948-958, 2016 | 35 | 2016 |
| Caspases: structure-guided design of drugs to control cell death IT Weber, B Fang, J Agniswamy Mini reviews in medicinal chemistry 8 (11), 1154-1162, 2008 | 34 | 2008 |
Manashree DamleMassachusetts General HospitalVerified email at molbio.mgh.harvard.edu
