| The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity J Barretina, G Caponigro, N Stransky, K Venkatesan, AA Margolin, S Kim, ... Nature 483 (7391), 603-307, 2012 | 7734 | 2012 |
| Next-generation characterization of the cancer cell line encyclopedia M Ghandi, FW Huang, J Jané-Valbuena, GV Kryukov, CC Lo, ... Nature 569 (7757), 503-508, 2019 | 2419 | 2019 |
| Variable generalization performance of a deep learning model to detect pneumonia in chest radiographs: a cross-sectional study JR Zech, MA Badgeley, M Liu, AB Costa, JJ Titano, EK Oermann PLoS medicine 15 (11), e1002683, 2018 | 1258 | 2018 |
| Characterization of the novel and specific PI3Kα inhibitor NVP-BYL719 and development of the patient stratification strategy for clinical trials C Fritsch, A Huang, C Chatenay-Rivauday, C Schnell, A Reddy, M Liu, ... Molecular cancer therapeutics 13 (5), 1117-1129, 2014 | 474 | 2014 |
| CDK 4/6 inhibitors sensitize PIK3CA mutant breast cancer to PI3K inhibitors SR Vora, D Juric, N Kim, M Mino-Kenudson, T Huynh, C Costa, ... Cancer cell 26 (1), 136-149, 2014 | 443 | 2014 |
| mTORC1 inhibition is required for sensitivity to PI3K p110α inhibitors in PIK3CA-mutant breast cancer M Elkabets, S Vora, D Juric, N Morse, M Mino-Kenudson, T Muranen, ... Science translational medicine 5 (196), 196ra99-196ra99, 2013 | 315 | 2013 |
| AXL mediates resistance to PI3Kα inhibition by activating the EGFR/PKC/mTOR axis in head and neck and esophageal squamous cell carcinomas M Elkabets, E Pazarentzos, D Juric, Q Sheng, RA Pelossof, S Brook, ... Cancer cell 27 (4), 533-546, 2015 | 309 | 2015 |
| Network-based analysis of affected biological processes in type 2 diabetes models M Liu, A Liberzon, SW Kong, WR Lai, PJ Park, IS Kohane, S Kasif PLoS genetics 3 (6), e96, 2007 | 226 | 2007 |
| Deep learning predicts hip fracture using confounding patient and healthcare variables MA Badgeley, JR Zech, L Oakden-Rayner, BS Glicksberg, M Liu, W Gale, ... NPJ digital medicine 2 (1), 31, 2019 | 216 | 2019 |
| Defects in muscle branched-chain amino acid oxidation contribute to impaired lipid metabolism C Lerin, AB Goldfine, T Boes, M Liu, S Kasif, JM Dreyfuss, ... Molecular metabolism 5 (10), 926-936, 2016 | 142 | 2016 |
| Loss of tuberous sclerosis complex 2 (TSC2) is frequent in hepatocellular carcinoma and predicts response to mTORC1 inhibitor everolimus H Huynh, HX Hao, SL Chan, D Chen, R Ong, KC Soo, P Pochanard, ... Molecular cancer therapeutics 14 (5), 1224-1235, 2015 | 116 | 2015 |
| mTOR Inhibitors Synergize on Regression, Reversal of Gene Expression, and Autophagy in Hepatocellular Carcinoma HE Thomas, CA Mercer, LS Carnevalli, J Park, JB Andersen, EA Conner, ... Science Translational Medicine 4 (139), 139ra84-139ra84, 2012 | 108 | 2012 |
| Accelerated postnatal growth increases lipogenic gene expression and adipocyte size in low–birth weight mice E Isganaitis, J Jimenez-Chillaron, M Woo, A Chow, J DeCoste, M Vokes, ... Diabetes 58 (5), 1192-1200, 2009 | 101 | 2009 |
| Confounding variables can degrade generalization performance of radiological deep learning models JR Zech, MA Badgeley, M Liu, AB Costa, JJ Titano, EK Oermann arXiv preprint arXiv:1807.00431, 2018 | 96 | 2018 |
| The HSP90 inhibitor NVP-AUY922 potently inhibits non–small cell lung cancer growth EB Garon, RS Finn, H Hamidi, J Dering, S Pitts, N Kamranpour, AJ Desai, ... Molecular cancer therapeutics 12 (6), 890-900, 2013 | 87 | 2013 |
| A systems biology approach identifies inflammatory abnormalities between mouse strains prior to development of metabolic disease MA Mori, M Liu, O Bezy, K Almind, H Shapiro, S Kasif, CR Kahn Diabetes 59 (11), 2960-2971, 2010 | 76 | 2010 |
| Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity J Barretina, G Caponigro, N Stransky, K Venkatesan, AA Margolin, S Kim, ... Nature 565 (7738), E5-E6, 2019 | 66 | 2019 |
| Carboxyl-ester lipase maturity-onset diabetes of the young is associated with development of pancreatic cysts and upregulated MAPK signaling in secretin-stimulated duodenal fluid H Ræder, FE McAllister, E Tjora, S Bhatt, I Haldorsen, J Hu, SM Willems, ... Diabetes 63 (1), 259-269, 2014 | 57 | 2014 |
| Single agent activity of PIK3CA inhibitor BYL719 in a broad cancer cell line panel A Huang, C Fritsch, C Wilson, A Reddy, M Liu, J Lehar, C Quadt, ... Cancer research 72 (8_Supplement), 3749-3749, 2012 | 38 | 2012 |
| CANDI: an R package and Shiny app for annotating radiographs and evaluating computer-aided diagnosis MA Badgeley, M Liu, BS Glicksberg, M Shervey, J Zech, K Shameer, ... Bioinformatics 35 (9), 1610-1612, 2019 | 7 | 2019 |
Alan HuangTango Therapeuticsכתובת אימייל מאומתת בדומיין tangotx.com
