Procollagen lysyl hydroxylase 2 is essential for hypoxia-induced breast cancer metastasis DM Gilkes, S Bajpai, CC Wong, P Chaturvedi, ME Hubbi, D Wirtz, ... Molecular cancer research 11 (5), 456-466, 2013 | 332 | 2013 |
Collagen prolyl hydroxylases are essential for breast cancer metastasis DM Gilkes, P Chaturvedi, S Bajpai, CC Wong, H Wei, S Pitcairn, ... Cancer research 73 (11), 3285-3296, 2013 | 325 | 2013 |
Regulation of cell proliferation by hypoxia-inducible factors ME Hubbi, GL Semenza American Journal of Physiology-Cell Physiology 309 (12), C775-C782, 2015 | 298 | 2015 |
Chaperone-mediated autophagy targets HIF-1α for lysosomal degradation ME Hubbi, H Hu, Kshitiz, I Ahmed, A Levchenko, GL Semenza Journal of Biological Chemistry, 2013 | 255 | 2013 |
Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis CCL Wong, H Zhang, DM Gilkes, J Chen, H Wei, P Chaturvedi, ME Hubbi, ... Journal of molecular medicine 90, 803-815, 2012 | 254 | 2012 |
Hypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cells DM Gilkes, L Xiang, SJ Lee, P Chaturvedi, ME Hubbi, D Wirtz, ... Proceedings of the National Academy of Sciences 111 (3), E384-E393, 2014 | 230 | 2014 |
Calcineurin promotes hypoxia-inducible factor 1α expression by dephosphorylating RACK1 and blocking RACK1 dimerization YV Liu, ME Hubbi, F Pan, KR McDonald, M Mansharamani, RN Cole, ... Journal of Biological Chemistry 282 (51), 37064-37073, 2007 | 189 | 2007 |
Sirtuin-7 Inhibits the Activity of Hypoxia-Inducible Factors ME Hubbi, H Hu, Kshitiz, DM Gilkes, GL Semenza Journal of Biological Chemistry, 2013 | 150 | 2013 |
A Nontranscriptional Role for HIF-1 {alpha} as a Direct Inhibitor of DNA Replication ME Hubbi, Kshitiz, DM Gilkes, S Rey, CC Wong, W Luo, DH Kim, ... Science signaling 6 (262), ra10, 2013 | 111 | 2013 |
Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression ME Hubbi, DM Gilkes, H Hu, Kshitiz, I Ahmed, GL Semenza Proceedings of the National Academy of Sciences 111 (32), E3325-E3334, 2014 | 110 | 2014 |
MCM proteins are negative regulators of hypoxia-inducible factor 1 ME Hubbi, W Luo, JH Baek, GL Semenza Molecular cell 42 (5), 700-712, 2011 | 108 | 2011 |
A calcineurin–Hoxb13 axis regulates growth mode of mammalian cardiomyocytes NUN Nguyen, DC Canseco, F Xiao, Y Nakada, S Li, NT Lam, ... Nature 582 (7811), 271-276, 2020 | 95 | 2020 |
Spermidine/spermine-N1-acetyltransferase 2 is an essential component of the ubiquitin ligase complex that regulates hypoxia-inducible factor 1α JH Baek, YV Liu, KR McDonald, JB Wesley, ME Hubbi, H Byun, ... Journal of Biological Chemistry 282 (32), 23572-23580, 2007 | 91 | 2007 |
Matrix Rigidity Controls Endothelial Differentiation and Morphogenesis of Cardiac Precursors Kshitiz, ME Hubbi, EH Ahn, J Downey, J Afzal, DH Kim, S Rey, C Chang, ... Science Signalling 5 (227), ra41, 2012 | 72 | 2012 |
Four-and-a-half LIM domain proteins inhibit transactivation by hypoxia-inducible factor 1 ME Hubbi, DM Gilkes, JH Baek, GL Semenza Journal of Biological Chemistry 287 (9), 6139-6149, 2012 | 70 | 2012 |
Huntington’s disease: Neural dysfunction linked to inositol polyphosphate multikinase I Ahmed, JI Sbodio, MM Harraz, R Tyagi, JC Grima, LK Albacarys, ... Proceedings of the National Academy of Sciences 112 (31), 9751-9756, 2015 | 37 | 2015 |
An essential role for chaperone-mediated autophagy in cell cycle progression ME Hubbi, GL Semenza Autophagy 11 (5), 850-851, 2015 | 32 | 2015 |
Control of the interface between heterotypic cell populations reveals the mechanism of intercellular transfer of signaling proteins DA Kshitiz, J Afzal, Y Suhail, EH Ahn, R Goyal, ME Hubbi, Q Hussaini, ... Integrative biology 7 (3), 364-372, 2015 | 11 | 2015 |
Bcl-xL enforces a slow-cycling state necessary for survival in the nutrient-deprived microenvironment of pancreatic cancer Y Sela, J Li, S Maheswaran, R Norgard, S Yuan, M Hubbi, M Doepner, ... Cancer research 82 (10), 1890-1908, 2022 | 9 | 2022 |
Lactate-dependent chaperone-mediated autophagy induces oscillatory HIF-1α activity promoting proliferation of hypoxic cells J Afzal, Y Suhail, H Chang, ME Hubbi, A Hamidzadeh, R Goyal, Y Liu, ... Cell systems 13 (12), 1048-1064. e7, 2022 | 7 | 2022 |