Incidence, characterization and prognostic significance of chromosomal abnormalities in 640 patients with primary myelodysplastic syndromes Solé, Espinet, Sanz, Cervera, Calasanz, Luño, Prieto, Granada, ... British journal of haematology 108 (2), 346-356, 2000 | 389 | 2000 |
The t (10; 11)(p13; q14) in the U937 cell line results in the fusion of the AF10 gene and CALM, encoding a new member of the AP-3 clathrin assembly protein family. MH Dreyling, JA Martinez-Climent, M Zheng, J Mao, JD Rowley, ... Proceedings of the National Academy of Sciences 93 (10), 4804-4809, 1996 | 368 | 1996 |
Transformation of follicular lymphoma to diffuse large cell lymphoma is associated with a heterogeneous set of DNA copy number and gene expression alterations JA Martinez-Climent, AA Alizadeh, R Segraves, D Blesa, ... Blood, The Journal of the American Society of Hematology 101 (8), 3109-3117, 2003 | 284 | 2003 |
Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas C Mestre-Escorihuela, F Rubio-Moscardo, JA Richter, R Siebert, ... Blood 109 (1), 271-280, 2007 | 283 | 2007 |
MALT1 small molecule inhibitors specifically suppress ABC-DLBCL in vitro and in vivo L Fontan, C Yang, V Kabaleeswaran, L Volpon, MJ Osborne, E Beltran, ... Cancer cell 22 (6), 812-824, 2012 | 265 | 2012 |
MALT1 is deregulated by both chromosomal translocation and amplification in B-cell non-Hodgkin lymphoma D Sanchez-Izquierdo, G Buchonnet, R Siebert, RD Gascoyne, J Climent, ... Blood 101 (11), 4539-4546, 2003 | 236 | 2003 |
Characterization of 8p21. 3 chromosomal deletions in B-cell lymphoma: TRAIL-R1 and TRAIL-R2 as candidate dosage-dependent tumor suppressor genes F Rubio-Moscardo, D Blesa, C Mestre, R Siebert, T Balasas, A Benito, ... Blood 106 (9), 3214-3222, 2005 | 231 | 2005 |
Mantle-cell lymphoma genotypes identified with CGH to BAC microarrays define a leukemic subgroup of disease and predict patient outcome F Rubio-Moscardo, J Climent, R Siebert, MA Piris, JI Martín-Subero, ... Blood 105 (11), 4445-4454, 2005 | 230 | 2005 |
Acquired mutations in BCL2 family proteins conferring resistance to the BH3 mimetic ABT-199 in lymphoma V Fresquet, M Rieger, C Carolis, MJ García-Barchino, ... Blood, The Journal of the American Society of Hematology 123 (26), 4111-4119, 2014 | 205 | 2014 |
The molecular signature of mantle cell lymphoma reveals multiple signals favoring cell survival N Martínez, FI Camacho, P Algara, A Rodríguez, A Dopazo, ... Cancer research 63 (23), 8226-8232, 2003 | 195 | 2003 |
KLF2 mutation is the most frequent somatic change in splenic marginal zone lymphoma and identifies a subset with distinct genotype DMQ Clipson A, Wang M, de Leval L, Ashton-Key M, Wotherspoon A, Vassiliou G ... Leukemia, [Epub ahead of print], 2015 | 179* | 2015 |
BCR-ABL Induces the Expression of Skp2 through the PI3K Pathway to Promote p27Kip1 Degradation and Proliferation of Chronic Myelogenous Leukemia Cells EJ Andreu, E Lledó, E Poch, C Ivorra, MP Albero, JA Martínez-Climent, ... Cancer research 65 (8), 3264-3272, 2005 | 168 | 2005 |
Molecular heterogeneity in MCL defined by the use of specificVH genes and the frequency of somatic mutations FI Camacho, P Algara, A Rodrıguez, E Ruız-Ballesteros, M Mollejo, ... Blood, The Journal of the American Society of Hematology 101 (10), 4042-4046, 2003 | 168 | 2003 |
Comprehensive whole genome array CGH profiling of mantle cell lymphoma model genomes RJ de Leeuw, JJ Davies, A Rosenwald, G Bebb, RD Gascoyne, MJS Dyer, ... Human molecular genetics 13 (17), 1827-1837, 2004 | 149 | 2004 |
C/EBPα induces highly efficient macrophage transdifferentiation of B lymphoma and leukemia cell lines and impairs their tumorigenicity F Rapino, EF Robles, JA Richter-Larrea, EM Kallin, JA Martinez-Climent, ... Cell reports 3 (4), 1153-1163, 2013 | 146 | 2013 |
Clinical and prognostic significance of chromosomal abnormalities in childhood acute myeloid leukemia de novo. JA Martinez-Climent, NJ Lane, CM Rubin, E Morgan, HS Johnstone, ... Leukemia 9 (1), 95-101, 1995 | 136 | 1995 |
Reversion of epigenetically mediated BIM silencing overcomes chemoresistance in Burkitt lymphoma JA Richter-Larrea, EF Robles, V Fresquet, E Beltran, AJ Rullan, X Agirre, ... Blood, The Journal of the American Society of Hematology 116 (14), 2531-2542, 2010 | 133 | 2010 |
Co-amplified genes at 8p12 and 11q13 in breast tumors cooperate with two major pathways in oncogenesis SS Kwek, R Roy, H Zhou, J Climent, JA Martinez-Climent, J Fridlyand, ... Oncogene 28 (17), 1892-1903, 2009 | 124 | 2009 |
Loss of a novel tumor suppressor gene locus at chromosome 8p is associated with leukemic mantle cell lymphoma JA Martinez-Climent, E Vizcarra, D Sanchez, D Blesa, I Marugan, I Benet, ... Blood, The Journal of the American Society of Hematology 98 (12), 3479-3482, 2001 | 120 | 2001 |
Cellular plasticity confers migratory and invasive advantages to a population of glioblastoma-initiating cells that infiltrate peritumoral tissue P Ruiz-Ontañon, JL Orgaz, B Aldaz, A Elosegui-Artola, J Martino, ... Stem cells 31 (6), 1075-1085, 2013 | 111 | 2013 |